ALZHEIMER'S DISEASE NEUROIMAGING

Research Front Map for the Special Topic of Alzheimer's Disease, March 2011

Research front maps are diagrammatic representations of the core papers comprising each front. They are selected from the current Research Front set that are relevant to the featured special topic, in this case, Alzheimer's Disease. The title for this Research Front Map is "ALZHEIMER'S DISEASE NEUROIMAGING," containing 50 core papers. Source dates: November 2004-October 31, 2010, the fifth bimonthly period of 2010 (sliding 6-year period).

Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The solid lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together); weaker links are indicated by dashed lines. Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in pink. Annotations may have been added to this map which represent the main research themes. These appear as labels attached to specific regions on the maps. Note: For best results use the "landscape orientation" option when printing this page.

ALZHEIMER'S DISEASE NEUROIMAGING

In-vivo imaging of Alzheimer disease beta-amyloid with [C-11]SB-13 PET Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B Association between CSF biomarkers and incipient Alzheimer Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid A beta(42) in humans [(11)]PIB in a nondemented population - Potential antecedent marker of Alzheimer disease Two-year follow-up of amyloid deposition in patients with Alzheimer PET of brain amyloid and tau in mild cognitive impairment Amyloid, hypometabolism, and cognition in Alzheimer disease - An [11C]PIB and [18F]FDG PET study Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults PET amyloid ligand [C-11]PIB uptake is increased in mild cognitive impairment Imaging beta-amyloid burden in aging and dementia beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer Core candidate neurochemical and imaging biomarkers of Alzheimer Imaging of amyloid beta in Alzheimer C-II PiB and structural MRI provide complementary information in imaging of Alzheimers disease and amnestic mild cognitive impairment The Alzheimer Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer A beta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer PET imaging of amyloid deposition in patients with mild cognitive impairment Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer Influence of Cognitive Status, Age, and APOE-4 Genetic Risk on Brain FDDNP Positron-Emission Tomography Imaging in Persons Without Dementia Tensor-based morphometry as a neuroimaging biomarker for Alzheimer The Cortical Signature of Alzheimer Detection of Alzheimer Pathology In Vivo Using Both C-11-PIB and F-18-FDDNP PET Baseline and longitudinal patterns of brain atrophy in MCI patients, and their use in prediction of short-term conversion to AD: Results from ADNI Decreased Cerebrospinal Fluid A beta(42) Correlates with Brain Atrophy in Cognitively Normal Elderly Cerebrospinal Fluid beta-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain Alzheimer MRI of hippocampal volume loss in early Alzheimers disease in relation to ApoE genotype and biomarkers Cerebrospinal Fluid Biomarker Signature in Alzheimer Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer Alzheimer Disease: Quantitative Structural Neuroimaging for Detection and Prediction of Clinical and Structural Changes in Mild Cognitive Impairment Episodic memory loss is related to hippocampal-mediated -amyloid deposition in elderly subjects Serial PIB and MRI in normal, mild cognitive impairment and Alzheimers disease: implications for sequence of pathological events in Alzheimers disease Prevalence and prognostic value of CSF markers of Alzheimer CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment MRI and CSF biomarkers in normal, MCI, and AD subjects Diagnostic discrimination and cognitive correlations MRI and CSF biomarkers in normal, MCI, and AD subjects Predicting future clinical change APOE Predicts Amyloid-Beta but Not Tau Alzheimer Pathology in Cognitively Normal Aging Hypothetical model of dynamic biomarkers of the Alzheimer Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer beta-Amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia Subregional neuroanatomical change as a biomarker for Alzheimer Alzheimer Optimizing power to track brain degeneration in Alzheimer Combining MR Imaging, Positron-Emission Tomography, and CSF Biomarkers in the Diagnosis and Prognosis of Alzheimer Disease Cerebrospinal fluid and plasma biomarkers in Alzheimer disease The clinical use of structural MRI in Alzheimer disease Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer

Core Papers


Label: Hansson-2006
Title: Association between CSF biomarkers and incipient Alzheimer's disease in patients with mild cognitive impairment: a follow-up study
Journal: LANCET NEUROL, 5 (3): 228-234 MAR 2006
Citations: 300
Authors: Hansson, O;Zetterberg, H;Buchhave, P;Londos, E;Blennow, K;Minthon, L
Addresses:
Univ Gothenburg, Sahlgrenska Univ Hosp, Inst Clin Neurosci, Dept Expt Neurosci, S-43180 Gothenburg, Sweden
Univ Gothenburg, Sahlgrenska Univ Hosp, Inst Clin Neurosci, Dept Expt Neurosci, S-43180 Gothenburg, Sweden
Lund Univ, Dept Clin Sci Malmo, Clin Memory Res Unit, S-22100 Lund, Sweden
Malmo Univ Hosp, Neuropsychiat Clin, Malmo, Sweden
Gothenburg Univ, Sahlgrenska Univ Hosp, Dept Clin Chem & Transfus Med, S-41124 Gothenburg, Sweden


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Label: Fagan-2006
Title: Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid A beta(42) in humans
Journal: ANN NEUROL, 59 (3): 512-519 MAR 2006
Citations: 225
Authors: Fagan, AM;Mintun, MA;Mach, RH;Lee, SY;Dence, CS;Shah, AR;LaRossa, GN;Spinner, ML;Klunk, WE;Mathis, CA;DeKosky, ST;Morris, JC;Holtzman, DM
Addresses:
Washington Univ, Sch Med, Dept Neurol, 660 S Euclid Ave,Box 8111, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Alzheimers Dis Res Ctr, St Louis, MO 63110 USA
Washington Univ, Sch Med, Hope Ctr Neurol Disorders, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Radiol, St Louis, MO 63110 USA
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA USA
Univ Pittsburgh, Dept Radiol, Pittsburgh, PA USA
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA USA
Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO USA
Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, St Louis, MO USA


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Label: Small-2006
Title: PET of brain amyloid and tau in mild cognitive impairment
Journal: N ENGL J MED, 355 (25): 2652-2663 DEC 21 2006
Citations: 207
Authors: Small, GW;Kepe, V;Ercoli, LM;Siddarth, P;Bookheimer, SY;Miller, KJ;Lavretsky, H;Burggren, AC;Cole, GM;Vinters, HV;Thompson, PM;Huang, SC;Satyamurthy, N;Phelps, ME;Barrio, JR
Addresses:
Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Suite 88-201,760 Westwood Plaza, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, David Geffen Sch Med, Dept Psychiat & Behav Sci, Los Angeles, CA USA
Univ Calif Los Angeles, Dept Mol & Med Pharmacol, Los Angeles, CA USA
Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Dept Neurol, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Dept Pathol & Lab Med, Los Angeles, CA USA
Univ Calif Los Angeles, Brain Mapping Ctr, Los Angeles, CA USA
Univ Calif Los Angeles, Lab Neuro Imaging, Los Angeles, CA USA
Univ Calif Los Angeles, Alzheimers Dis Ctr, Los Angeles, CA USA
Univ Calif Los Angeles, Ctr Aging, Los Angeles, CA USA


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Label: Mintun-2006
Title: [(11)]PIB in a nondemented population - Potential antecedent marker of Alzheimer disease
Journal: NEUROLOGY, 67 (3): 446-452 AUG 8 2006
Citations: 200
Authors: Mintun, MA;LaRossa, GN;Sheline, YI;Dence, CS;Lee, SY;Mach, RH;Klunk, WE;Mathis, CA;DeKosky, ST;Morris, JC
Addresses:
Washington Univ, Sch Med, Mallinckrodt Inst Radiol, Dept Radiol, Box 8225,510 S Kingshighway Blvd, St Louis, MO 63110 USA
Washington Univ, Sch Med, Mallinckrodt Inst Radiol, Dept Radiol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Mallinckrodt Inst Radiol, Dept Psychiat, St Louis, MO 63110 USA
Washington Univ, Sch Med, Mallinckrodt Inst Radiol, Dept Neurol, St Louis, MO 63110 USA
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA


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Label: Rowe-2007
Title: Imaging beta-amyloid burden in aging and dementia
Journal: NEUROLOGY, 68 (20): 1718-1725 MAY 15 2007
Citations: 191
Authors: Rowe, CC;Ng, S;Ackermann, U;Gong, SJ;Pike, K;Savage, G;Cowie, TF;Dickinson, KL;Maruff, P;Darby, D;Smith, C;Woodward, M;Merory, J;Tochon-Danguy, H;O'Keefe, G;Klunk, WE;Mathis, CA;Price, JC;Masters, CL;Villemagne, VL
Addresses:
Austin Hlth, Ctr PET, Dept Nucl Med, 145 Studley Rd, Melbourne, Vic 3084, Australia
Austin Hlth, Ctr PET, Dept Nucl Med, Melbourne, Vic 3084, Australia
Univ Melbourne, Austin Hlth, Dept Med & Aged Care, Melbourne, Vic, Australia
Monash Univ, Sch Psychol, Dept Psychiat & Psychol Med, Melbourne, Vic, Australia
Univ Melbourne, Dept Pathol, Cogstate Pty Ltd, Melbourne, Vic, Australia
Mental Hlth Res Inst, Parkville, Vic, Australia
Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15260 USA


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Label: Verhoeff-2004
Title: In-vivo imaging of Alzheimer disease beta-amyloid with [C-11]SB-13 PET
Journal: AMER J GERIATR PSYCHIATR, 12 (6): 584-595 NOV-DEC 2004
Citations: 158
Authors: Verhoeff, NPLG;Wilson, AA;Takeshita, S;Trop, L;Hussey, D;Singh, K;Kung, HF;Kung, MP;Houle, S
Addresses:
Univ Toronto, Dept Psychiat, Posluns Bldg,Room 762,3560 Bathurst St, Toronto, ON M6A 2E1, Canada
Univ Toronto, Dept Psychiat, Toronto, ON M6A 2E1, Canada
Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA


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Label: Engler-2006
Title: Two-year follow-up of amyloid deposition in patients with Alzheimer's disease
Journal: BRAIN, 129: 2856-2866 Part 11 NOV 2006
Citations: 140
Authors: Engler, H;Forsberg, A;Almkvist, O;Blomquist, G;Larsson, E;Savitcheva, I;Wall, A;Ringheim, A;Langstrom, B;Nordberg, A
Addresses:
Karolinska Univ Hosp Huddinge, Karolinska Inst, Dept Neurobiol Care Sci & Soc, Div Mol Neuropharmacol,Novum, S-14186 Huddinge, Sweden
Uppsala Imanet AB, GE Healthcare, Uppsala, Sweden
Univ Uppsala Hosp, Uppsala, Sweden
Uppsala Univ, Dept Oncol Radiol & Clin Immunol, Uppsala, Sweden
Uppsala Univ, Dept Biochem & Organ Chem, Uppsala, Sweden
Karolinska Inst, Div Mol Neuropharmacol, Dept Neurobiol Care Sci & Soc, Stockholm, Sweden
Karolinska Univ Hosp Huddinge, Dept Geriatr Med, Stockholm, Sweden
Stockholm Univ, Dept Psychol, S-10691 Stockholm, Sweden


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Label: Price-2005
Title: Kinetic modeling of amyloid binding in humans using PET imaging and Pittsburgh Compound-B
Journal: J CEREBR BLOOD FLOW METABOL, 25 (11): 1528-1547 NOV 2005
Citations: 138
Authors: Price, JC;Klunk, WE;Lopresti, BJ;Lu, XL;Hoge, JA;Ziolko, SK;Holt, DP;Meltzer, CC;DeKosky, ST;Mathis, CA
Addresses:
Univ Pittsburgh, Sch Med, PET Facil, Dept Radiol, 200 Lothrup St,Rm B-938, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, PET Facil, Dept Radiol, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Neurol, Pittsburgh, PA 15213 USA


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Label: Fagan-2007
Title: Cerebrospinal fluid tau/beta-amyloid(42) ratio as a prediction of cognitive decline in nondemented older adults
Journal: ARCH NEUROL, 64 (3): 343-349 MAR 2007
Citations: 130
Authors: Fagan, AM;Roe, CM;Xiong, CJ;Mintun, MA;Morris, JC;Holtzman, DM
Addresses:
Washington Univ, Dept Neurol, Sch Med, 660 S Euclid Ave,Box 8111, St Louis, MO 63110 USA
Washington Univ, Dept Neurol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Biostat, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Radiol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Pathol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Immunol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Mol Biol & Pharmacol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Hope Ctr Neurol Disorders, Sch Med, St Louis, MO 63110 USA
Washington Univ, Alzheimers Dis Res Ctr, Sch Med, St Louis, MO 63110 USA


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Label: Pike-2007
Title: beta-amyloid imaging and memory in non-demented individuals: evidence for preclinical Alzheimer's disease
Journal: BRAIN, 130: 2837-2844 Part 11 NOV 2007
Citations: 124
Authors: Pike, KE;Savage, G;Villemagne, VL;Ng, S;Moss, SA;Maruff, P;Mathis, CA;Klunk, WE;Masters, CL;Rowe, CC
Addresses:
Austin Hlth, Ctr PET, Dept Nucl Med, Studley Rd, Heidelberg, Vic 3084, Australia
Austin Hlth, Ctr PET, Dept Nucl Med, Heidelberg, Vic 3084, Australia
Monash Univ, Sch Psychol Psychiat & Psychol Med, Melbourne, Vic 3004, Australia
Univ Melbourne, Ctr Neurosci, Parkville, Vic 3052, Australia
Mental Hlth Res Inst, Parkville, Vic, Australia
Cogstate Pty Ltd, Melbourne, Vic, Australia
Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15260 USA
Univ Melbourne, Austin Hlth, Dept Med, Parkville, Vic 3052, Australia


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Label: Jack-2008
Title: The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods
Journal: J MAGN RESON IMAGING, 27 (4): 685-691 APR 2008
Citations: 102
Authors: Jack, CR;Bernstein, MA;Fox, NC;Thompson, P;Alexander, G;Harvey, D;Borowski, B;Britson, PJ;Whitwell, JL;Ward, C;Dale, AM;Felmlee, JP;Gunter, JL;Hill, DLG;Killiany, R;Schuff, N;Fox-Bosetti, S;Lin, C;Studholme, C;DeCarli, CS;Krueger, G;Ward, HA;Metzger, GJ;Scott, KT;Mallozzi, R;Blezek, D;Levy, J;Debbins, JP;Fleisher, AS;Albert, M;Green, R;Bartzokis, G;Glover, G;Mugler, J;Weiner, MW;ADNI Study
Addresses:
Mayo Clin, Dept Radiol, 200 1st St SW, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Rochester, MN 55905 USA
Natl Hosp Neurol & Neurosurg, London WC1N 3BG, England
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neuro Imaging, Los Angeles, CA 90024 USA
Arizona State Univ, Dept Psychol, Neuroimage Anal Lab, Tempe, AZ 85287 USA
Univ Calif Davis, Dept Publ Hlth Sci, Davis, CA 95616 USA
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Coll London, Ctr Med Image Comp, London WC1E 6BT, England
Boston Univ, Sch Med, Dept Anat & Neurobiol, Boston, MA 02118 USA
Univ Calif San Francisco, San Francisco, CA 94143 USA
CIND, Dept Vet Affairs Med Ctr, San Francisco, CA USA
Univ Calif Davis, Sch Med, Dept Neurol, Davis, CA 95616 USA
Univ Calif Davis, Sch Med, Alzheimers Dis Ctr, Davis, CA 95616 USA
Siemens Med Solut, Erlangen, Germany
Phantom Lab, Greenwich, NY USA
Massachusetts Gen Hosp, Dept Psychiat & Neurol, Boston, MA 02114 USA
Johns Hopkins Univ, Sch Med, Div Cognit Neurosci, Baltimore, MD USA
Boston Univ, Sch Med, Genet Program & Alzheimers Dis Ctr, Boston, MA 02118 USA
Stanford Univ, Lucas Magnet Resonance Imaging Ctr, Dept Radiol, Stanford, CA 94305 USA
Univ Virginia, Sch Med, Dept Radiol, Charlottesville, VA 22908 USA


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Label: Edison-2007
Title: Amyloid, hypometabolism, and cognition in Alzheimer disease - An [11C]PIB and [18F]FDG PET study
Journal: NEUROLOGY, 68 (7): 501-508 FEB 13 2007
Citations: 99
Authors: Edison, P;Archer, HA;Hinz, R;Hammers, A;Pavese, N;Tai, YF;Hotton, G;Cutler, D;Fox, N;Kennedy, A;Rossor, M;Brooks, DJ
Addresses:
Hammersmith Hosp, Imperial Coll London, MRC Clin Sci Ctr, Cyclotron Bldg,Du Cane Rd, London W12 0NN, England
Hammersmith Hosp, Imperial Coll London, MRC Clin Sci Ctr, London W12 0NN, England
Hammersmith Hosp, Imperial Coll London, Div Neurosci, London W12 0NN, England
UCL, Dementia Res Ctr, Inst Neurol, London, England
GE Healthcare, Hammersmith Imanet, London, England


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Label: Ikonomovic-2008
Title: Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
Journal: BRAIN, 131: 1630-1645 Part 6 JUN 2008
Citations: 95
Authors: Ikonomovic, MD;Klunk, WE;Abrahamson, EE;Mathis, CA;Price, JC;Tsopelas, ND;Lopresti, BJ;Ziolko, S;Bi, WZ;Paljug, WR;Debnath, ML;Hope, CE;Isanski, BA;Hamilton, RL;DeKosky, ST
Addresses:
Univ Pittsburgh, Sch Med, Dept Neurol, 3471 5th Ave,Suite 811, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Neurol, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Psychiat, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Radiol, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Neuropathol, Pittsburgh, PA 15213 USA


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Label: Forsberg-2008
Title: PET imaging of amyloid deposition in patients with mild cognitive impairment
Journal: NEUROBIOL AGING, 29 (10): 1456-1465 OCT 2008
Citations: 90
Authors: Forsberg, A;Engler, H;Almkvist, O;Blomquist, G;Hagman, G;Wall, A;Ringheim, A;Langstrom, B;Nordberg, A
Addresses:
Karolinska Univ, Huddinge Hosp, Div Mol Neuropharmacol, Care Sci & Soc,Dept Neurobiol,Karolinska Inst, Novum 5th Floor, S-14186 Stockholm, Sweden
Karolinska Inst, Dept Neurobiol, Care Sci & Soc, Stockholm, Sweden
Karolinska Univ, Huddinge Hosp, Dept Geriatr Med, Stockholm, Sweden
Univ Uppsala Hosp, Dept Nucl Med, Uppsala, Sweden
Uppsala Univ, Dept Oncol Radiol & Clin Immunol, Uppsala, Sweden
GE Healthcare, Imanet, Uppsala Imanet AB, Uppsala, Sweden
Uppsala Univ, Dept Biochem & Organ Chem, Uppsala, Sweden
Stockholm Univ, Dept Psychol, S-10691 Stockholm, Sweden


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Label: Rowe-2008
Title: Imaging of amyloid beta in Alzheimer's disease with F-18-BAY94-9172, a novel PET tracer: proof of mechanism
Journal: LANCET NEUROL, 7 (2): 129-135 FEB 2008
Citations: 88
Authors: Rowe, CC;Ackerman, U;Browne, W;Mulligan, R;Pike, KL;O'Keefe, G;Tochon-Danguy, H;Chan, G;Berlangieri, SU;Jones, G;Dickinson-Rowe, KL;Kung, HP;Zhang, W;Kung, MP;Skovronsky, D;Dyrks, T;Hall, G;Krause, S;Friebe, M;Lehman, L;Lindemann, S;Dinkelborg, LM;Masters, CL;Villemagne, VL
Addresses:
Ctr PET, Austin Hlth, Dept Nucl Med, 145 Studley Rd, Heidelberg, Vic 3084, Australia
Ctr PET, Austin Hlth, Dept Nucl Med, Heidelberg, Vic 3084, Australia
Univ Melbourne, Dept Med, Parkville, Vic 3052, Australia
Univ Penn, Dept Radiol, Philadelphia, PA 19104 USA
AVID Radiopharmaceut, Philadelphia, PA USA
Bayer Schering Pharma, Berlin, Germany
Univ Melbourne, Mental Hlth Res Inst Victoria, Dept Pathol, Parkville, Vic 3052, Australia


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Label: Kemppainen-2007
Title: PET amyloid ligand [C-11]PIB uptake is increased in mild cognitive impairment
Journal: NEUROLOGY, 68 (19): 1603-1606 MAY 8 2007
Citations: 84
Authors: Kemppainen, NM;Aalto, S;Wilson, IA;Nagren, K;Helin, S;Bruck, A;Oikonen, V;Kailajarvi, M;Scheinin, M;Viitanen, M;Parkkola, R;Rinne, JO
Addresses:
Univ Turku, Turku PET Ctr, Dept Pharmacol, POB 52, FIN-20521 Turku, Finland
Univ Turku, Turku PET Ctr, Dept Pharmacol, FIN-20521 Turku, Finland
Univ Turku, CRST, FIN-20521 Turku, Finland
Abo Akad Univ, Dept Psychol, Turku, Finland
Turku Univ, Cent Hosp, Dept Clin Radiol, Turku, Finland
Turku City Hosp, Turku, Finland
Turku Imanet, Turku, Finland
Karolinska Inst, Stockholm, Sweden


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Label: Jack-2008
Title: C-II PiB and structural MRI provide complementary information in imaging of Alzheimers disease and amnestic mild cognitive impairment
Journal: BRAIN, 131: 665-680 Part 3 MAR 2008
Citations: 83
Authors: Jack, CR;Lowe, VJ;Senjem, ML;Weigand, SD;Kemp, BJ;Shiung, MM;Knopman, DS;Boeve, BF;Klunk, WE;Mathis, CA;Petersen, RC
Addresses:
Mayo Clin, 200 1st St SW, Rochester, MN 55905 USA
Neurol Mayo Clin & Fdn, Informat Serv, Rochester, MN 55905 USA
Neurol Mayo Clin & Fdn, Div Biostat, Rochester, MN 55905 USA
Neurol Mayo Clin & Fdn, Dept Diagnost Radiol, Rochester, MN 55905 USA
Univ Pittsburgh, Sch Med, Pittsburgh, PA USA


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Label: Shaw-2009
Title: Cerebrospinal Fluid Biomarker Signature in Alzheimer's Disease Neuroimaging Initiative Subjects
Journal: ANN NEUROL, 65 (4): 403-413 APR 2009
Citations: 80
Authors: Shaw, LM;Vanderstichele, H;Knapik-Czajka, M;Clark, CM;Aisen, PS;Petersen, RC;Blennow, K;Soares, H;Simon, A;Lewczuk, P;Dean, R;Siemers, E;Potter, W;Lee, VMY;Trojanowski, JQ;Alzheimer's Dis Neuroimaging Initi
Addresses:
Univ Penn, Dept Pathol & Lab Med, Med Ctr, 7 Founders,3400 Spruce St, Philadelphia, PA 19104 USA
Univ Penn, Sch Med, Ctr Neurodegenerat Dis Res,Inst Aging, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Innogenet NV, Dept Diagnost Dev, Ghent, Belgium
Univ Penn, Sch Med, Dept Neurol, Inst Aging,Ctr Neurodegenerat Dis Res, Philadelphia, PA 19104 USA
Univ Calif San Diego, San Diego, CA 92103 USA
Mayo Clin, Coll Med, Rochester, MN USA
Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Clin Neurochem Lab,Dept Psychiat & Neurochem, Molndal, Sweden
Pfizer Global Res & Dev, Groton, CT USA
Merck Res Labs, West Point, PA USA
Univ Erlangen Nurnberg, Dept Psychiat & Psychotherapy, Erlangen, Germany
Eli Lilly & Co, Indianapolis, IN 46285 USA


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Label: Aizenstein-2008
Title: Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly
Journal: ARCH NEUROL, 65 (11): 1509-1517 NOV 2008
Citations: 72
Authors: Aizenstein, HJ;Nebes, RD;Saxton, JA;Price, JC;Mathis, CA;Tsopelas, ND;Ziolko, SK;James, JA;Snitz, BE;Houck, PR;Bi, WZ;Cohen, AD;Lopresti, BJ;DeKosky, ST;Halligan, EM;Klunk, WE
Addresses:
Univ Pittsburgh, Sch Med, Dept Psychiat, Western Psychiat Inst & Clin, 3811 OHara St, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Psychiat, Western Psychiat Inst & Clin, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Neurol, Pittsburgh, PA 15213 USA
Univ Pittsburgh, Sch Med, Dept Radiol, Pittsburgh, PA 15213 USA


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Label: Jack-2009
Title: Serial PIB and MRI in normal, mild cognitive impairment and Alzheimers disease: implications for sequence of pathological events in Alzheimers disease
Journal: BRAIN, 132: 1355-1365 Part 5 MAY 2009
Citations: 71
Authors: Jack, CR;Lowe, VJ;Weigand, SD;Wiste, HJ;Senjem, ML;Knopman, DS;Shiung, MM;Gunter, JL;Boeve, BF;Kemp, BJ;Weiner, M;Petersen, RC;Alzheimer's Dis Neuroimaging Initi
Addresses:
Mayo Clin, 200 1st St SW, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Diagnost Radiol, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Div Biomed Stat & Informat, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Neurol, Rochester, MN 55905 USA
Univ Calif San Francisco, Dept Vet Affairs Med Ctr, San Francisco, CA 94143 USA
Ctr Imaging Neurodegenerat Dis, San Francisco, CA USA


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Label: Mattsson-2009
Title: CSF Biomarkers and Incipient Alzheimer Disease in Patients With Mild Cognitive Impairment
Journal: JAMA-J AM MED ASSN, 302 (4): 385-393 JUL 22 2009
Citations: 59
Authors: Mattsson, N;Zetterberg, H;Hansson, O;Andreasen, N;Parnetti, L;Jonsson, M;Herukka, SK;van der Flier, WM;Blankenstein, MA;Ewers, M;Rich, K;Kaiser, E;Verbeek, M;Tsolaki, M;Mulugeta, E;Rosen, E;Aarsland, D;Visser, PJ;Schroder, J;Marcusson, J;de Leon, M;Hampel, H;Scheltens, P;Pirttila, T;Wallin, A;Jonhagen, ME;Minthon, L;Winblad, B;Blennow, K
Addresses:
Sahlgrenska Univ Hosp Molndal, Clin Neurochem Lab, S-43180 Molndal, Sweden
Univ Gothenburg, Sahlgrenska Acad, Dept Neurochem & Psychiat, Inst Neurosci & Physiol, Molndal, Sweden
Lund Univ, Clin Memory Res Unit, Lund, Sweden
Huddinge Univ Hosp, Karolinska Inst, Stockholm, Sweden
Univ Perugia, I-06100 Perugia, Italy
Univ Kuopio, Dept Neurol, Kuopio, Finland
Univ Kuopio, Brain Res Unit, Clin Res Ctr Mediteknia, FIN-70211 Kuopio, Finland
Kuopio Univ Hosp, SF-70210 Kuopio, Finland
Vrije Univ Amsterdam, Med Ctr, Dept Neurol, Amsterdam, Netherlands
Vrije Univ Amsterdam, Med Ctr, Alzheimer Ctr, Amsterdam, Netherlands
Univ Dublin, Adelaide & Meath Hosp Incorporating Natl Children, Trinity Coll, Lab Neuroimaging & Biomarker Res,TCIN, Dublin, Ireland
Univ Dublin, Adelaide & Meath Hosp Incorporating Natl Children, Dept Psychiat, Sch Med, Dublin, Ireland
Univ Munich, Dept Psychiat, Alzheimer Mem Ctr, D-8000 Munich, Germany
NYU, Sch Med, Ctr Brain Hlth, New York, NY USA
Univ Heidelberg, Sekt Gerontopsychiat, D-6900 Heidelberg, Germany
Radboud Univ Nijmegen, Med Ctr, Lab Pediat & Neurol, NL-6525 ED Nijmegen, Netherlands
Aristotle Univ Thessaloniki, Mem & Dementia Ctr, Dept Neurol 3, G Papanicolaore Gen Hosp, Thessaloniki, Greece
Stavanger Univ Hosp, Ctr Clin Neurosci Res, Stavanger, Norway
Univ Maastricht, Dept Psychiat & Neuropsychol, Inst Brain & Behav, Maastricht, Netherlands
Linkoping Univ, Dept Neurosci & Locomot, Div Geriatr Med, Linkoping, Sweden


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Label: Reiman-2009
Title: Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
Journal: PROC NAT ACAD SCI USA, 106 (16): 6820-6825 APR 21 2009
Citations: 56
Authors: Reiman, EM;Chen, KW;Liu, XF;Bandy, D;Yu, MX;Lee, WD;Ayutyanont, N;Keppler, J;Reeder, SA;Langbaum, JBS;Alexander, GE;Klunk, WE;Mathis, CA;Price, JC;Aizenstein, HJ;DeKosky, ST;Caselli, RJ
Addresses:
Good Samaritan Reg Med Ctr, Banner Alzheimers Inst, Phoenix, AZ 85006 USA
Good Samaritan Reg Med Ctr, Banner Alzheimers Inst, Phoenix, AZ 85006 USA
Good Samaritan Reg Med Ctr, Positron Emiss Tomog Ctr, Phoenix, AZ 85006 USA
Univ Arizona, Dept Psychiat, Tucson, AZ 85721 USA
Univ Arizona, Dept Radiol, Tucson, AZ 85721 USA
Univ Arizona, Dept Psychol, Tucson, AZ 85721 USA
Univ Arizona, Evelyn F McKnight Brain Inst, Tucson, AZ 85721 USA
Translat Genom Res Inst, Neurogenom Div, Phoenix, AZ 85004 USA
Arizona State Univ, Dept Math, Tempe, AZ 85287 USA
Arizona State Univ, Biodesign Inst, Tempe, AZ 85287 USA
Univ Pittsburgh, Dept Psychiat, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Neurol, Pittsburgh, PA 15260 USA
Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15260 USA
Mayo Clin, Dept Neurol, Scottsdale, AZ 85259 USA
Arizona Alzheimers Consortium, Phoenix, AZ 85006 USA


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Label: Hampel-2008
Title: Core candidate neurochemical and imaging biomarkers of Alzheimer's disease
Journal: ALZHEIMERS DEMENT, 4 (1): 38-48 JAN 2008
Citations: 54
Authors: Hampel, H;Buerger, K;Teipel, SJ;Bokde, ALW;Zetterberg, H;Blennow, K
Addresses:
AMiNCH, Sch Med, Discipline Psychiat, Dublin, Ireland
AMiNCH, Sch Med, Discipline Psychiat, Dublin, Ireland
Univ Dublin Trinity Coll, Trin Ctr Hlth Sci, TCIN, AMiNCH, Dublin 2, Ireland
Univ Munich, Alzheimer Mem Ctr, Dept Psychiat, Munich, Germany
Univ Gothenburg, Sahlgrenska Acad, Inst Neurosci & Physiol, Dept Psychiat & Neurochem, Molndal, Sweden


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Label: Schuff-2009
Title: MRI of hippocampal volume loss in early Alzheimers disease in relation to ApoE genotype and biomarkers
Journal: BRAIN, 132: 1067-1077 Part 4 APR 2009
Citations: 44
Authors: Schuff, N;Woerner, N;Boreta, L;Kornfield, T;Shaw, LM;Trojanowski, JQ;Thompson, PM;Jack, CR;Weiner, MW;Alzheimer's Dis Neuroimaging Initi
Addresses:
4150 Clement St 114M, San Francisco, CA 94121 USA
Dept Vet Affairs Med Ctr, San Francisco, CA USA
Univ Calif San Francisco, Dept Radiol, San Francisco, CA 94143 USA
Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neuro Imaging, Los Angeles, CA 90024 USA
Mayo Clin, Coll Med, Rochester, MN USA


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Label: Jack-2010
Title: Hypothetical model of dynamic biomarkers of the Alzheimer's pathological cascade
Journal: LANCET NEUROL, 9 (1): 119-128 JAN 2010
Citations: 41
Authors: Jack, CR;Knopman, DS;Jagust, WJ;Shaw, LM;Aisen, PS;Weiner, MW;Petersen, RC;Trojanowski, JQ
Addresses:
Mayo Clin, Dept Radiol, 200 1st St SW, Rochester, MN 55905 USA
Mayo Clin, Dept Radiol, Rochester, MN 55905 USA
Mayo Clin, Dept Neurol, Rochester, MN 55905 USA
Univ Calif Berkeley, Sch Publ Hlth & Helen Wills, Inst Neurosci, Berkeley, CA 94720 USA
Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Univ Penn, Sch Med, Inst Aging, Philadelphia, PA 19104 USA
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Calif San Francisco, San Francisco, CA 94143 USA


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Label: Tapiola-2009
Title: Cerebrospinal Fluid beta-Amyloid 42 and Tau Proteins as Biomarkers of Alzheimer-Type Pathologic Changes in the Brain
Journal: ARCH NEUROL, 66 (3): 382-389 MAR 2009
Citations: 38
Authors: Tapiola, T;Alafuzoff, I;Herukka, SK;Parkkinen, L;Hartikainen, P;Soininen, H;Pirttila, T
Addresses:
Univ Kuopio, Kuopio Univ Hosp, Dept Neurol, POB 1777, FIN-70211 Kuopio, Finland
Univ Kuopio, Kuopio Univ Hosp, Dept Neurol, FIN-70211 Kuopio, Finland
Univ Kuopio, Kuopio Univ Hosp, Dept Pathol, FIN-70211 Kuopio, Finland
Univ Kuopio, Kuopio Univ Hosp, Dept Neurosci & Neurol, FIN-70211 Kuopio, Finland
Univ Kuopio, Kuopio Univ Hosp, Clin Res Ctr Mediteknia, Brain Res Unit, FIN-70211 Kuopio, Finland


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Label: Dickerson-2009
Title: The Cortical Signature of Alzheimer's Disease: Regionally Specific Cortical Thinning Relates to Symptom Severity in Very Mild to Mild AD Dementia and is Detectable in Asymptomatic Amyloid-Positive Individuals
Journal: CEREB CORTEX, 19 (3): 497-510 MAR 2009
Citations: 37
Authors: Dickerson, BC;Bakkour, A;Salat, DH;Feczko, E;Pacheco, J;Greve, DN;Grodstein, F;Wright, CI;Blacker, D;Rosas, HD;Sperling, RA;Atri, A;Growdon, JH;Hyman, BT;Morris, JC;Fischl, B;Buckner, RL
Addresses:
Gerontol Res Unit, 149 13th St,Suite 2691, Charlestown, MA 02129 USA
Massachusetts Gen Hosp, Dept Neurol, Boston, MA 02114 USA
Massachusetts Gen Hosp, Massachusetts Alzheimers Dis Res Ctr, Boston, MA 02114 USA
Massachusetts Gen Hosp, Athinoula A Martinos Ctr Biomed Imaging, Boston, MA 02114 USA
Brigham & Womens Hosp, Div Cognit & Behav Neurol, Dept Neurol, Boston, MA 02115 USA
Massachusetts Gen Hosp, Dept Radiol, Boston, MA 02114 USA
Massachusetts Gen Hosp, Dept Psychiat, Boston, MA 02114 USA
Brigham & Womens Hosp, Dept Internal Med, Boston, MA 02115 USA
Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Alzheimers Dis Res Ctr, St Louis, MO 63110 USA
MIT, Comp Sci & Artificial Intelligence Lab, Cambridge, MA 02139 USA
Harvard Univ, Dept Psychol, Cambridge, MA 02138 USA
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Sch Med, Boston, MA USA


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Label: Hua-2008
Title: Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: An MRI study of 676 AD, MCI, and normal subjects
Journal: NEUROIMAGE, 43 (3): 458-469 NOV 15 2008
Citations: 35
Authors: Hua, X;Leow, AD;Parikshak, N;Lee, S;Chiang, MC;Toga, AW;Jack, CR;Weiner, MW;Thompson, PM;Alzheimer's Dis Neuroimaging Initi
Addresses:
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neuro Imaging, Neurosci Res Bldg 225E,635 Charles Young Dr, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neuro Imaging, Los Angeles, CA 90095 USA
Mayo Clin, Coll Med, Rochester, MN USA
UC San Francisco, Dept Radiol, San Francisco, CA USA
UC San Francisco, Dept Med & Psychiat, San Francisco, CA USA
Dept Vet Affairs Med Ctr, Los Angeles, CA USA


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Label: Villemagne-2008
Title: A beta deposits in older non-demented individuals with cognitive decline are indicative of preclinical Alzheimer's disease
Journal: NEUROPSYCHOLOGIA, 46 (6): 1688-1697 2008
Citations: 33
Authors: Villemagne, VL;Pike, KE;Darby, D;Maruff, P;Savage, G;Ng, S;Ackermann, U;Cowie, TF;Currie, J;Chan, SG;Jones, G;Tochon-Danguy, H;O'Keefe, G;Masters, CL;Rowe, CC
Addresses:
Austin Hlth, Dept Nucl Med, Ctr PET, 145 Studley Rd, Heidelberg, Vic 3084, Australia
Austin Hlth, Dept Nucl Med, Ctr PET, Heidelberg, Vic 3084, Australia
Mental Hlth Res Inst, Parkville, Vic, Australia
Univ Melbourne, Dept Pathol, Melbourne, Vic 3010, Australia
Univ Melbourne, Ctr Neurosci, Melbourne, Vic 3010, Australia
Monash Univ, Sch Psychol Psychiat & Psychol Med, Melbourne, Vic 3004, Australia
Cogstate Pty Ltd, Melbourne, Vic, Australia
St Vincents Hosp, Melbourne, Vic, Australia
Austin Hlth Univ Melbourne, Dept Med, Melbourne, Vic, Australia


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Label: Fagan-2009
Title: Decreased Cerebrospinal Fluid A beta(42) Correlates with Brain Atrophy in Cognitively Normal Elderly
Journal: ANN NEUROL, 65 (2): 176-183 FEB 2009
Citations: 32
Authors: Fagan, AM;Head, D;Shah, AR;Marcus, D;Mintun, M;Morris, JC;Holtzman, DM
Addresses:
Washington Univ, Dept Neurol, Sch Med, 660 S Euclid Ave,Campus Box 8111, St Louis, MO 63110 USA
Washington Univ, Dept Neurol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Hope Ctr Neurol Disorders, Sch Med, St Louis, MO 63110 USA
Washington Univ, Alzheimer Dis Res Ctr, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Radiol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Psychol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Pathol & Immunol, Sch Med, St Louis, MO 63110 USA
Washington Univ, Dept Dev Biol, Sch Med, St Louis, MO 63110 USA


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Label: Mormino-2009
Title: Episodic memory loss is related to hippocampal-mediated -amyloid deposition in elderly subjects
Journal: BRAIN, 132: 1310-1323 Part 5 MAY 2009
Citations: 32
Authors: Mormino, EC;Kluth, JT;Madison, CM;Rabinovici, GD;Baker, SL;Miller, BL;Koeppe, RA;Mathis, CA;Weiner, MW;Jagust, WJ;Alzheimer's Dis Neuroimaging Initi
Addresses:
Univ Calif Berkeley, Helen Wills Neurosci Inst, 132 Barker Hall,MC 3190, Berkeley, CA 94720 USA
Univ Calif Berkeley, Helen Wills Neurosci Inst, Berkeley, CA 94720 USA
Lawrence Berkeley Natl Lab, Dept Mol Imaging & Neurosci, Berkeley, CA USA
Univ Calif San Francisco, Memory & Aging Ctr, San Francisco, CA 94143 USA
Univ Calif San Francisco, Dept Neurol, San Francisco, CA 94143 USA
Univ Michigan, Dept Radiol, Div Nucl Med, Ann Arbor, MI 48109 USA
Univ Pittsburgh, Dept Radiol, Pittsburgh, PA 15260 USA
Ctr Imaging Neurodegenerat Dis, Dept Vet Affairs Med Ctr, San Francisco, CA USA


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Label: Li-2008
Title: Regional analysis of FDG and PIB-PET images in normal aging, mild cognitive impairment, and Alzheimer's disease
Journal: EUR J NUCL MED MOL IMAGING, 35 (12): 2169-2181 DEC 2008
Citations: 28
Authors: Li, Y;Rinne, JO;Mosconi, L;Pirraglia, E;Rusinek, H;DeSanti, S;Kemppainen, N;Nagren, K;Kim, BC;Tsui, W;de Leon, MJ
Addresses:
HN400 NYU Sch Med, Ctr Brain Hlth, Dept Psychiat, New York, NY 10016 USA
HN400 NYU Sch Med, Ctr Brain Hlth, Dept Psychiat, New York, NY 10016 USA
Shandong Univ, Qilu Hosp, Jinan, Peoples R China
Univ Turku, Turku PET Ctr, FIN-20520 Turku, Finland
Chonnam Natl Univ, Dept Neurol, Sch Med, Kwangju, South Korea
Nathan S Kline Inst Psychiat Res, Orangeburg, NY USA
NYU, Sch Med, New York, NY USA


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Label: McEvoy-2009
Title: Alzheimer Disease: Quantitative Structural Neuroimaging for Detection and Prediction of Clinical and Structural Changes in Mild Cognitive Impairment
Journal: RADIOLOGY, 251 (1): 195-205 APR 2009
Citations: 28
Authors: McEvoy, LK;Fennema-Notestine, C;Roddey, JC;Hagler, DJ;Holland, D;Karow, DS;Pung, CJ;Brewer, JB;Dale, AM;Alzheimers Dis Neuroimaging Initia
Addresses:
Univ Calif San Diego, Dept Radiol, 9500 Gilman Dr, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Radiol, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA


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Label: Leow-2009
Title: Alzheimer's Disease Neuroimaging Initiative: A one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition
Journal: NEUROIMAGE, 45 (3): 645-655 APR 15 2009
Citations: 27
Authors: Leow, AD;Yanovsky, I;Parikshak, N;Hua, X;Lee, S;Toga, AW;Jack, CR;Bernstein, MA;Britson, PJ;Gunter, JL;Ward, CP;Borowski, B;Shaw, LM;Trojanowski, JQ;Fleisher, AS;Harvey, D;Kornak, J;Schuff, N;Alexander, GE;Weiner, MW;Thompson, PM;Alzheimer's Dis Neuroimaging
Addresses:
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neruo Imaging, Neurosci Res Bldg 225E,635 Charles Young Dr, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neruo Imaging, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Resnick Neuropsychiat Hosp, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Math, Los Angeles, CA 90095 USA
Mayo Clin, Rochester, MN USA
Univ Penn, Sch Med, Dept Pathol, Philadelphia, PA 19104 USA
Univ Penn, Sch Med, Lab Med, Philadelphia, PA 19104 USA
Univ Penn, Sch Med, Inst Aging, Philadelphia, PA 19104 USA
UC San Diego, Dept Neurosci, La Jolla, CA USA
UC Davis Sch Med, Dept Publ Hlth Sci, Davis, CA USA
UC San Francisco, Dept Radiol & Biomed Imaging, San Francisco, CA USA
UC San Francisco, Dept Epidemiol & Biostat, San Francisco, CA USA
UC San Francisco, Vet Affairs Med Ctr, San Francisco, CA USA
UC San Francisco, Dept Radiol, San Francisco, CA USA
UC San Francisco, Dept Med & Psychiat, San Francisco, CA USA
Univ Arizona, Dept Psychol, Tucson, AZ 85721 USA
Univ Arizona, Evelyn F McKnight Brain Inst, Tucson, AZ USA


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Label: Misra-2009
Title: Baseline and longitudinal patterns of brain atrophy in MCI patients, and their use in prediction of short-term conversion to AD: Results from ADNI
Journal: NEUROIMAGE, 44 (4): 1415-1422 FEB 15 2009
Citations: 26
Authors: Misra, C;Fan, Y;Davatzikos, C
Addresses:
Univ Penn, Sch Med, Dept Radiol, Sect Biomed Image Anal, 3600 Market St,Suite 380, Philadelphia, PA 19104 USA
Univ Penn, Sch Med, Dept Radiol, Sect Biomed Image Anal, Philadelphia, PA 19104 USA


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Label: Tolboom-2009
Title: Detection of Alzheimer Pathology In Vivo Using Both C-11-PIB and F-18-FDDNP PET
Journal: J NUCL MED, 50 (2): 191-197 FEB 2009
Citations: 25
Authors: Tolboom, N;Yaqub, M;van der Flier, WM;Boellaard, R;Luurtsema, G;Windhorst, AD;Barkhof, F;Scheltens, P;Lammertsma, AA;van Berckel, BNM
Addresses:
Vrije Univ Amsterdam, Med Ctr, Dept Neurol, POB 7057, NL-1007 MB Amsterdam, Netherlands
Vrije Univ Amsterdam, Med Ctr, Dept Neurol, NL-1007 MB Amsterdam, Netherlands
Vrije Univ Amsterdam, Med Ctr, Alzheimer Ctr, NL-1007 MB Amsterdam, Netherlands
Vrije Univ Amsterdam, Med Ctr, Dept Nucl Med & PET Res, NL-1007 MB Amsterdam, Netherlands
Vrije Univ Amsterdam, Med Ctr, Dept Radiol, NL-1007 MB Amsterdam, Netherlands


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Label: Vemuri-2009
Title: MRI and CSF biomarkers in normal, MCI, and AD subjects Diagnostic discrimination and cognitive correlations
Journal: NEUROLOGY, 73 (4): 287-293 JUL 28 2009
Citations: 25
Authors: Vemuri, P;Wiste, HJ;Weigand, SD;Shaw, LM;Trojanowski, JQ;Weiner, MW;Knopman, DS;Petersen, RC;Jack, CR;Alzheimers Dis Neuroimaging Initia
Addresses:
Mayo Clin & Mayo Fdn, Dept Radiol, Aging & Dementia Imaging Res Lab, 200 1st St SW, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Radiol, Aging & Dementia Imaging Res Lab, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Hlth Sci Res, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Neurol, Rochester, MN 55905 USA
Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Univ Calif San Francisco, San Francisco, CA 94143 USA
Ctr Imaging Neurodegenerat Dis, Dept Vet Affairs Med Ctr, San Francisco, CA USA


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Label: Vemuri-2009
Title: MRI and CSF biomarkers in normal, MCI, and AD subjects Predicting future clinical change
Journal: NEUROLOGY, 73 (4): 294-301 JUL 28 2009
Citations: 25
Authors: Vemuri, P;Wiste, HJ;Weigand, SD;Shaw, LM;Trojanowski, JQ;Weiner, MW;Knopman, DS;Petersen, RC;Jack, CR;Alzheimers Dis Neuroimaging Initia
Addresses:
Mayo Clin & Mayo Fdn, Dept Radiol, Aging & Dementia Imaging Res Lab, 200 1st St SW, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Radiol, Aging & Dementia Imaging Res Lab, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Hlth Sci Res, Rochester, MN 55905 USA
Mayo Clin & Mayo Fdn, Dept Neurol, Rochester, MN 55905 USA
Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA
Univ Calif San Francisco, San Francisco, CA 94143 USA
Ctr Imaging Neurodegenerat Dis, Dept Vet Affairs Med Ctr, San Francisco, CA USA


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Label: Visser-2009
Title: Prevalence and prognostic value of CSF markers of Alzheimer's disease pathology in patients with subjective cognitive impairment or mild cognitive impairment in the DESCRIPA study: a prospective cohort study
Journal: LANCET NEUROL, 8 (7): 619-627 JUL 2009
Citations: 25
Authors: Visser, PJ;Verhey, F;Knol, DL;Scheltens, P;Wahlund, LO;Freund-Levi, Y;Tsolaki, M;Minthon, L;Wallin, AK;Hampel, H;Burger, K;Pirttila, T;Soininen, H;Rikkert, MO;Verbeek, MM;Spiru, L;Blennow, K
Addresses:
Univ Maastricht, Dept Psychiat, POB 616, NL-6200 MD Maastricht, Netherlands
Univ Maastricht, Dept Psychiat, NL-6200 MD Maastricht, Netherlands
Univ Maastricht, Dept Psychiat & Neuropsychol, Alzheimer Ctr Limburg, NL-6200 MD Maastricht, Netherlands
Vrije Univ Amsterdam Med Ctr, Dept Neurol, Alzheimer Ctr, Amsterdam, Netherlands
Vrije Univ Amsterdam Med Ctr, Dept Clin Epidemiol & Stat, Amsterdam, Netherlands
Radboud Univ Nijmegen, Med Ctr, Alzheimer Ctr,Nijmegen Ctr Evidence Based Practic, Dept Geriatr, NL-6525 ED Nijmegen, Netherlands
Radboud Univ Nijmegen, Med Ctr, Donders Ctr Brain Cognit & Behav,Alzheimer Ctr, Dept Neurol, NL-6525 ED Nijmegen, Netherlands
Karolinska Univ Hosp, Karolinska Inst, Dept NVS, Sect Clin Geriatr, Huddinge, Sweden
Lund Univ, Dept Clin Sci Malmo, Clin Memory Res Unit, S-22100 Lund, Sweden
Gothenburg Univ, Sahlgrenska Univ Hosp, Clin Neurochem Lab, Molndal, Sweden
Aristotle Univ Thessaloniki, Dept Neurol 3, Memory & Dementia Ctr, G Papanicolaou Gen Hosp, GR-54006 Thessaloniki, Greece
Univ Munich, Dept Psychiat, Alzheimer Mem Ctr, D-8000 Munich, Germany
Univ Dublin Trinity Coll, Adelaide & Meath Hosp Incorporating, Natl Childrens Hosp, Discipline Psychiat,Sch Med, Dublin 2, Ireland
Univ Dublin Trinity Coll, Adelaide & Meath Hosp Incorporating, Natl Childrens Hosp, Lab Neuroimaging & Biomarker Res,TCIN, Dublin 2, Ireland
Univ Kuopio, Dept Neurol, Kuopio, Finland
Kuopio Univ Hosp, SF-70210 Kuopio, Finland
Carol Davila Univ Med & Pharm, Bucharest, Romania


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Label: Hua-2009
Title: Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: An ADNI study of 515 subjects
Journal: NEUROIMAGE, 48 (4): 668-681 DEC 2009
Citations: 16
Authors: Hua, X;Lee, S;Yanovsky, I;Leow, AD;Chou, YY;Ho, AJ;Gutman, B;Toga, AW;Jack, CR;Bernstein, MA;Reiman, EM;Harvey, DJ;Kornak, J;Schuff, N;Alexander, GE;Weiner, MW;Thompson, PM;Alzheimer's Dis Neuroimaging
Addresses:
UCLA, Dept Neurol, Lab Neuro Imaging, Sch Med, Neurosci Res Bldg 225E,635 Charles Young Dr, Los Angeles, CA 90095 USA
UCLA, Dept Neurol, Lab Neuro Imaging, Sch Med, Los Angeles, CA 90095 USA
UCLA, Resnick Neuropsychiat Hosp, Los Angeles, CA 90095 USA
UCLA, Dept Math, Los Angeles, CA 90095 USA
Mayo Clin, Rochester, MN USA
Univ Arizona, Dept Psychiat, Banner Alzheimers Inst, Phoenix, AZ USA
UCD, Sch Med, Dept Publ Hlth Sci, Davis, CA USA
UCSF, Dept Radiol & Biomed Imaging, San Francisco, CA USA
Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA
Vet Affairs Med Ctr, San Francisco, CA 94121 USA
Univ Calif San Francisco, Dept Med, San Francisco, CA USA
Univ Calif San Francisco, Dept Psychiat, San Francisco, CA 94143 USA


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Label: Petersen-2010
Title: Alzheimer's Disease Neuroimaging Initiative (ADNI) Clinical characterization
Journal: NEUROLOGY, 74 (3): 201-209 JAN 19 2010
Citations: 16
Authors: Petersen, RC;Aisen, PS;Beckett, LA;Donohue, MC;Gamst, AC;Harvey, DJ;Jack, CR;Jagust, WJ;Shaw, LM;Toga, AW;Trojanowski, JQ;Weiner, MW
Addresses:
Mayo Clin, Coll Med, Dept Neurol, 200 1st St SW, Rochester, MN 55905 USA
Mayo Clin, Coll Med, Dept Neurol, Rochester, MN 55905 USA
Mayo Clin, Coll Med, Dept Radiol, Rochester, MN 55905 USA
Univ Calif Davis, Dept Neurosci, Davis, CA 95616 USA
Univ Calif Davis, Sch Med, Div Biostat, Davis, CA 95616 USA
Univ Calif San Diego, Dept Neurosci & Biostat, San Diego, CA 92103 USA
Univ Calif Berkeley, Helen Willis Neurosci Inst, Berkeley, CA 94720 USA
Univ Penn, Sch Med, Dept Lab Med, Philadelphia, PA 19104 USA
Univ Calif Los Angeles, Sch Med, Dept Neurol, Toga Lab Neuroimaging, Los Angeles, CA 90024 USA
Univ Calif San Francisco, Ctr Imaging Neurodegenerat Dis, San Francisco, CA 94143 USA


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Label: Small-2009
Title: Influence of Cognitive Status, Age, and APOE-4 Genetic Risk on Brain FDDNP Positron-Emission Tomography Imaging in Persons Without Dementia
Journal: ARCH GEN PSYCHIAT, 66 (1): 81-87 JAN 2009
Citations: 15
Authors: Small, GW;Siddarth, P;Burggren, AC;Kepe, V;Ercoli, LM;Miller, KJ;Lavretsky, H;Thompson, PM;Cole, GM;Huang, SC;Phelps, ME;Bookheimer, SY;Barrio, JR
Addresses:
Semel Inst, 760 Westwood Plaza,Ste 88-201, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, David Geffen Sch Med, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Semel Inst Neurosci & Human Behav, David Geffen Sch Med, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Dept Mol & Med Pharmacol, David Geffen Sch Med, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Dept Neurol, David Geffen Sch Med, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Alzheimers Dis Ctr, David Geffen Sch Med, Los Angeles, CA 90024 USA
Univ Calif Los Angeles, Ctr Aging, David Geffen Sch Med, Los Angeles, CA 90024 USA


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Label: Holland-2009
Title: Subregional neuroanatomical change as a biomarker for Alzheimer's disease
Journal: PROC NAT ACAD SCI USA, 106 (49): 20954-20959 DEC 8 2009
Citations: 10
Authors: Holland, D;Brewer, JB;Hagler, DJ;Fenema-Notestine, C;Dale, AM;Alzheimer's Dis Neuroimaging Initi
Addresses:
Multimodal Imaging Lab, Suite C101, La Jolla, CA 92037 USA
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Radiol, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA


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Label: Morris-2010
Title: APOE Predicts Amyloid-Beta but Not Tau Alzheimer Pathology in Cognitively Normal Aging
Journal: ANN NEUROL, 67 (1): 122-131 JAN 2010
Citations: 10
Authors: Morris, JC;Roe, CM;Xiong, CJ;Fagan, AM;Goate, AM;Holtzman, DM;Mintun, MA
Addresses:
Washington Univ, Sch Med, Alzheimer Dis Res Ctr, 4488 Forest Pk Ave,Suite 160, St Louis, MO 63108 USA
Washington Univ, Sch Med, Alzheimer Dis Res Ctr, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Phys Therapy, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Occupat Therapy, St Louis, MO 63108 USA
Washington Univ, Sch Med, Div Biostat, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Dev Biol, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Psychiat, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Genet, St Louis, MO 63108 USA
Washington Univ, Sch Med, Dept Radiol, St Louis, MO 63108 USA


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Label: Blennow-2010
Title: Cerebrospinal fluid and plasma biomarkers in Alzheimer disease
Journal: NAT REV NEUROL, 6 (3): 131-144 MAR 2010
Citations: 9
Authors: Blennow, K;Hampel, H;Weiner, M;Zetterberg, H
Addresses:
Univ Gothenburg, Clin Neurochem Lab, Inst Neurosci & Physiol, Dept Psychiat & Neurochem,Sahlgrenska Acad, SE-43180 Molndal, Sweden
Univ Gothenburg, Clin Neurochem Lab, Inst Neurosci & Physiol, Dept Psychiat & Neurochem,Sahlgrenska Acad, SE-43180 Molndal, Sweden
Trinity Coll Dublin, Sch Med, Discipline Psychiat, Dublin 24, Ireland
Univ Calif San Francisco, VA Med Ctr, MRS Unit, San Francisco, CA 94121 USA


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Label: Fagan-2009
Title: Cerebrospinal fluid tau and ptau(181) increase with cortical amyloid deposition in cognitively normal individuals: Implications for future clinical trials of Alzheimer's disease
Journal: EMBO MOL MED, 1 (8-9): 371-380 NOV-DEC 2009
Citations: 9
Authors: Fagan, AM;Mintun, MA;Shah, AR;Aldea, P;Roe, CM;Mach, RH;Marcus, D;Morris, JC;Holtzman, DM
Addresses:
Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Alzheimers Dis Res Ctr, St Louis, MO 63110 USA
Washington Univ, Sch Med, Hope Ctr Neurol Disorders, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Radiol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO 63110 USA
Washington Univ, Sch Med, Dept Mol Biol & Pharmacol, St Louis, MO 63110 USA


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Label: Walhovd-2010
Title: Combining MR Imaging, Positron-Emission Tomography, and CSF Biomarkers in the Diagnosis and Prognosis of Alzheimer Disease
Journal: AMER J NEURORADIOL, 31 (2): 347-354 FEB 2010
Citations: 9
Authors: Walhovd, KB;Fjell, AM;Brewer, J;McEvoy, LK;Fennema-Notestine, C;Hagler, DJ;Jennings, RG;Karow, D;Dale, AM;Alzheimers Dis Neuroimaging Initia
Addresses:
Univ Oslo, Dept Psychol, CSHC, POB 1094 Blindern, N-0317 Oslo, Norway
Univ Oslo, Dept Psychol, CSHC, N-0317 Oslo, Norway
Ullevaal Univ Hosp, Dept Neuropsychol, Oslo, Norway
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Radiol, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Psychiat, La Jolla, CA 92093 USA


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Label: Frisoni-2010
Title: The clinical use of structural MRI in Alzheimer disease
Journal: NAT REV NEUROL, 6 (2): 67-77 FEB 2010
Citations: 8
Authors: Frisoni, GB;Fox, NC;Jack, CR;Scheltens, P;Thompson, PM
Addresses:
IRCCS Ctr San Giovanni Dio FBF, Via Pilastroni 1, I-25125 Brescia, Italy
IRCCS Ctr San Giovanni Dio FBF, I-25125 Brescia, Italy
UCL Inst Neurol, Dementia Res Ctr, London WC1N 3BG, England
Mayo Clin, Rochester, MN 55905 USA
Vrije Univ Amsterdam, Med Ctr, Alzheimer Ctr, NL-1007 MB Amsterdam, Netherlands
Vrije Univ Amsterdam, Med Ctr, Dept Neurol, NL-1007 MB Amsterdam, Netherlands
Univ Calif Los Angeles, Lab Neuro Imaging, Dept Neurol, Sch Med, Los Angeles, CA 90095 USA


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Label: Bourgeat-2010
Title: beta-Amyloid burden in the temporal neocortex is related to hippocampal atrophy in elderly subjects without dementia
Journal: NEUROLOGY, 74 (2): 121-127 JAN 12 2010
Citations: 6
Authors: Bourgeat, P;Chetelat, G;Villemagne, VL;Fripp, J;Raniga, P;Pike, K;Acosta, O;Szoeke, C;Ourselin, S;Ames, D;Ellis, KA;Martins, RN;Masters, CL;Rowe, CC;Salvado, O;Grp, AR
Addresses:
Royal Brisbane & Womens Hosp, Australian e Hlth Res Ctr, CSIRO Preventat Hlth Natl Res Flagship ICTC, BioMedIA, Level 7,UQ CCR Bldg 71-918, Herston, Qld 4029, Australia
Royal Brisbane & Womens Hosp, Australian e Hlth Res Ctr, CSIRO Preventat Hlth Natl Res Flagship ICTC, BioMedIA, Herston, Qld 4029, Australia
Austin Hlth, Dept Nucl Med, Melbourne, Vic, Australia
Austin Hlth, Ctr PET, Melbourne, Vic, Australia
Univ Caen Basse Normandie, INSERM, EPHE, CHU Cote Nacre,Unite U923,GIP Cyceron, Caen, France
Univ Melbourne, Mental Hlth Res Inst, Melbourne, Vic 3010, Australia
Univ Melbourne, Ctr Neurosci, Melbourne, Vic 3010, Australia
Univ Melbourne, Dept Med, Melbourne, Vic 3010, Australia
UCL, Ctr Med Image Comp, London WC1E 6BT, England
Natl Ageing Res Inst, Melbourne, Vic, Australia
Univ Melbourne, Acad Unit Psychiat Old Age, Dept Psychiat, St Georges Hosp,St Vincents Aged Psychiat Serv, Melbourne, Vic 3010, Australia
Edith Cowan Univ, Ctr Excellence Alzheimers Dis Res & Care, Sch Exercise Biomed & Hlth Sci, Joondalup, WA, Australia


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Label: Stein-2010
Title: Genome-wide analysis reveals novel genes influencing temporal lobe structure with relevance to neurodegeneration in Alzheimer's disease
Journal: NEUROIMAGE, 51 (2): 542-554 JUN 2010
Citations: 6
Authors: Stein, JL;Hua, X;Morra, JH;Lee, S;Hibar, DP;Ho, AJ;Leow, AD;Toga, AW;Sul, JH;Kang, HM;Eskin, E;Saykin, AJ;Shen, L;Foroud, T;Pankratz, N;Huentelman, MJ;Craig, DW;Gerber, JD;Allen, AN;Corneveaux, JJ;Stephan, DA;Webster, J;DeChairo, BM;Potkin, SG;Jack, CR;Weiner, MW;Thompson, PM;Alzheimer's Dis Neuroimaging Initi
Addresses:
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neuro Imaging, Neurosci Res Bldg 225E,635 Charles Young Dr, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Sch Med, Dept Neurol, Lab Neuro Imaging, Los Angeles, CA 90095 USA
Univ Illinois, Sch Med, Chicago, IL USA
Community Psychiat Associates, Sacramento, CA USA
Univ Calif Los Angeles, Dept Comp Sci, Los Angeles, CA 90095 USA
Univ Michigan, Dept Biostat, Ann Arbor, MI 48109 USA
Univ Calif Los Angeles, Dept Human Genet, Los Angeles, CA 90095 USA
Indiana Univ, Sch Med, Dept Radiol & Imaging Sci, Ctr Neuroimaging, Indianapolis, IN 46202 USA
Indiana Univ, Sch Med, Dept Med & Mol Genet, Indianapolis, IN 46202 USA
Translat Genom Res Inst, Phoenix, AZ USA
Pfizer Global R&D, Mol Med, New London, CT USA
Univ Calif Irvine, Dept Psychiat & Human Behav, Irvine, CA 92717 USA
Mayo Clin, Rochester, MN USA
UC San Francisco, Dept Radiol, San Francisco, CA USA
UC San Francisco, Dept Med, San Francisco, CA USA
UC San Francisco, Dept Psychiat, San Francisco, CA USA
Dept Vet Affairs Med Ctr, San Francisco, CA USA
IGNITE Inst Individualized Hlth, Fairfax, VA USA


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KEYWORDS: ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE (ADNI) CLINICAL CHARACTERIZATION; ALZHEIMER'S DISEASE NEUROIMAGING INITIATIVE SUBJECTS; ALZHEIMER'S DISEASE PATHOLOGY; INCIPIENT ALZHEIMER'S DISEASE; PRECLINICAL ALZHEIMER'S DISEASE.
[6314;(2000-2010_5) (CLI/NEU: ST ALZHEIMER'S DISEASE) (MARCH 2011)]

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