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SPECIAL TOPICS

Autophagy

Published: July 2009
 

The baseline time span for this database is (publication years) 1999-February 28, 2009 from the first bimonthly update (a 10-year + 2-month period). The resulting database contained 3,228 (10 years) and 1,731 (2 years) papers; 9,874 authors; 66 nations; 738 journals; and 1,864 institutions. See additional information below in the overview & methodology sections.

Top 20 Papers

  10-year period
  2-year period

Top 20 Overall

  Authors
  Institutions
  Journals
  Nations

Research Front Map

  Map title: AUTOPHAGY

Time Series

  1- & 5-year periods

Field Distribution

Interviews

  Interviews, first-person essays, and profiles about people in a wide variety of fields which pertain to this special topic of Autophagy.
   

OVERVIEW

Autophagy, a process by which a cell self-degrades, sounds more deleterious than it actually is. In fact, autophagy is an essential process in cell growth, development, and homeostasis. Though the phenomenon was first discovered in the 1960s, autophagy's functions and mechanisms have gone largely undiscovered until more recently.

This month, Special Topics examines the literature on autophagy, both over the past decade and over the past two years. The initial data pool was constructed with the keyword "autophag*" in titles, abstracts, and keywords sections of original articles, reviews, and proceedings papers published between January 1999 and February 2009. To make the lists of papers more on-target, the top 20 papers over the past decade and over the past two years were limited to "autophag*" in the title only.

Three themes are prevalent among the top papers from the past decade: possible mechanisms of autophagy, the role of autophagy in disease (particularly cancer and neurodegenerative diseases), and the role of autophagy in nutrient starvation. These themes persist among papers on the two-year list as well. In addition, more recent papers speculate on the relationship between autophagy and apoptosis, as well as autophagy's role in hemodynamic stress, ischemia, and reperfusion in the heart.

Methodology: The baseline time span for this database is (publication years) 1999-February 28, 2009 from the first bimonthly update (a 10-year + 2-month period). The resulting database contained 3,228 (10 years) and 1,731 (2 years) papers; 9,874 authors; 66 nations; 738 journals; and 1,864 institutions. See additional paper and rankings information below.

Papers: To construct the top 20 papers lists for the past decade and the past two years, the papers were further narrowed down by the title keywords "autophag*." This adjustment resulted in the top 20 papers being selected from a pool of 1,266 (10 years) and 770 (2 years) papers.

Rankings: Once the database was in place, it was used to generate list of authors, journals, institutions, and nations. Rankings for author, journal, institution, and country are listed in three ways: according to total cites, total papers, and total cites/paper. The paper thresholds and corresponding percentages used to determine scientist, institution, country, and journal rankings according to total cites/paper, and total papers respectively are listed in the table below. In some cases, further thresholds are used, and noted only where applicable.

Entity Authors Institutions Nations Journals
Thresholds 18 9 13 1*
Percentage: %1 %10 %50 %50
*All rankings have a 5 paper threshold for all measures.

          



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