Archive ScienceWatch

 ScienceWatch
Sin-2003 Calverley-2003 Schumacher-2004 Corfas-2004 O Lipworth-2005 Harrison-2005 Anthonisen-2005 Craddock-2005 Decramer-2005 Green-2005 Callicott-2005 Rabe-2005 Niewoehner-2005 Hamshere-2005 Houslay-2005 Cannon-2005 Millar-2005 Sin-2005 Lugnier-2006 Barnes-2006 Williams-2006 Law-2006 Hahn-2006 Harrison-2006 Bender-2006 Crow-2007 Kardos-2007 Calverley-2007 Omori-2007 McClellan-2007 Craddock-2007 Aaron-2007 Li-2007 Clapcote-2007 Conti-2007 Rabe-2007 Wedzicha-2008 Munafo-2008 Shi-2008 Sanders-2008 Suissa-2008 Zheng-2008 Mei-2008 Celli-2008 Singh-2008 Tashkin-2008

Chronic Obstructive Pulmonary Disease


 Core Papers 


Label: Harrison-2005
Title: Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence
Journal: MOL PSYCHIATR, 10 (1): 40-68 JAN 2005
Citations: 473
Authors: Harrison, PJ;Weinberger, DR
Addresses:
Univ Oxford, Warneford Hosp, Dept Psychiat, Neurosci Bldg, Oxford OX3 7JX, England
Univ Oxford, Warneford Hosp, Dept Psychiat, Oxford OX3 7JX, England
NIMH, Genes Cognit & Psychosis Program, NIH, Bethesda, MD 20892 USA


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Label: Rabe-2007
Title: Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease - GOLD executive summary
Journal: AMER J RESPIR CRIT CARE MED, 176 (6): 532-555 SEP 15 2007
Citations: 342
Authors: Rabe, KF;Hurd, S;Anzueto, A;Barnes, PJ;Buist, SA;Calverley, P;Fukuchi, Y;Jenkins, C;Rodriguez-Roisin, R;van Weel, C;Zielinski, J
Addresses:
Leiden Univ, Med Ctr, POB 9600, NL-2300 RC Leiden, Netherlands
Leiden Univ, Med Ctr, NL-2300 RC Leiden, Netherlands
Global Initiat Chron Obstruct Lung Dis, Gaithersburg, MD USA
Univ Texas, Hlth Sci Ctr, San Antonio, TX 78285 USA
Natl Heart & Lung Inst, London, England
Oregon Hlth & Sci Univ, Portland, OR USA
Aintree Univ Hosp NHS Fdn Trust, Liverpool, Merseyside, England
Asian Pacific Soc Respirol, Tokyo, Japan
Woolcock Inst Med Res, Sydney, NSW, Australia
Hosp Clin Barcelona, Barcelona, Spain
Univ Nijmegen, Nijmegen, Netherlands
Inst TB & Lung Dis, Warsaw, Poland


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Label: Calverley-2007
Title: Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease
Journal: N ENGL J MED, 356 (8): 775-789 FEB 22 2007
Citations: 310
Authors: Calverley, PMA;Anderson, JA;Celli, B;Ferguson, GT;Jenkins, C;Jones, PW;Yates, JC;Vestbo, J;Calverley, PMA;Anderson, JA;Celli, B;Ferguson, GT;Jenkins, C;Jones, PW;Knobil, K;Yates, JC;Vestbo, J;Cherniack, R;Similowski, T;Cleland, J;Whitehead, A;Wise, R;McGarvey, L;John, M;TORCH Investigators
Addresses:
Univ Hosp Aintree, Dept Med, Ctr Clin Sci, Longmoor Lane, Liverpool L9 7AL, Merseyside, England
Univ Hosp Aintree, Dept Med, Ctr Clin Sci, Liverpool L9 7AL, Merseyside, England
GlaxoSmithKline Res & Dev Ltd, Greenford, Middx, England
Caritas St Elizabeths Med Ctr, Boston, MA USA
Pulm Res Inst SE Michigan, Livonia, MI USA
Woolcock Inst Med Res, Sydney, NSW, Australia
St Georges Univ London, London, England
GlaxoSmithKline Res & Dev Ltd, Res Triangle Pk, NC USA
Wythenshawe Hosp, Manchester M23 9LT, Lancs, England
Univ Copenhagen, Hvidovre Hosp, DK-2650 Hvidovre, Denmark


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Label: Anthonisen-2005
Title: The effects of a smoking cessation intervention on 14.5-year mortality - A randomized clinical trial
Journal: ANN INTERN MED, 142 (4): 233-239 FEB 15 2005
Citations: 206
Authors: Anthonisen, NR;Skeans, MA;Wise, RA;Manfreda, J;Kanner, RE;Connett, JE;Lung Hlth Study Research Grp
Addresses:
Univ Minnesota, Coordinating Ctr Biometr Res, 2221 Univ Ave SE,Room 200, Minneapolis, MN 55414 USA
Univ Minnesota, Minneapolis, MN USA
Johns Hopkins Univ, Baltimore, MD USA
Univ Utah, Salt Lake City, UT USA
Univ Manitoba, Winnipeg, MB, Canada


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Label: O'Donnell-2004
Title: Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD
Journal: EUR RESP J, 23 (6): 832-840 JUN 2004
Citations: 193
Authors: O'Donnell, DE;Fluge, T;Gerken, F;Hamilton, A;Webb, K;Aguilaniu, B;Make, B;Magnussen, H
Addresses:
102 Stuart St, Kingston, ON K7L 2V6, Canada
Queens Univ, Dept Med, Resp Invest Unit, Kingston, ON, Canada
Boehringer Ingelheim Pharma GmbH & Co KG, Ingelheim, Germany
UCP X, Clin Mail, Grenoble, France
Natl Jewish Med & Res Ctr, Denver, CO USA
Krankenhaus Grosshansdorf, D-2070 Grosshansdorf, Germany


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Label: Calverley-2003
Title: Maintenance therapy with budesonide and formoterol in chronic obstructive pulmonary disease
Journal: EUR RESP J, 22 (6): 912-919 DEC 2003
Citations: 188
Authors: Calverley, PM;Boonsawat, W;Cseke, Z;Zhong, N;Peterson, S;Olsson, H
Addresses:
Univ Hosp Aintree, Dept Med Clin Sci, Pulm & Rehabil Res Grp, Longmoor Lane, Liverpool L9 7AL, Merseyside, England
Univ Hosp Aintree, Dept Med Clin Sci, Pulm & Rehabil Res Grp, Liverpool L9 7AL, Merseyside, England
Khon Kaen Univ, Srinagarind Hosp, Khon Kaen, Thailand
Vas Megyei Markusovszky Korhaz, Szombathely, Hungary
Guangzhou Inst Resp Dis, Guangzhou, Peoples R China
AstraZeneca R&D, Lund, Sweden


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Label: Craddock-2005
Title: The genetics of schizophrenia and bipolar disorder: dissecting psychosis
Journal: J MED GENET, 42 (3): 193-204 MAR 2005
Citations: 177
Authors: Craddock, N;O'Donovan, MC;Owen, MJ
Addresses:
Cardiff Univ, Wales Sch Med, Dept Psychol Med, Henry Wellcome Bldg Biomed Res,Acad Ave,Heath Pk, Cardiff CF14 4XN, S Glam, Wales
Cardiff Univ, Wales Sch Med, Dept Psychol Med, Cardiff CF14 4XN, S Glam, Wales


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Label: Bender-2006
Title: Cyclic nucleotide phosphodiesterases: Molecular regulation to clinical use
Journal: PHARMACOL REV, 58 (3): 488-520 SEP 2006
Citations: 160
Authors: Bender, AT;Beavo, JA
Addresses:
Univ Washington, Sch Med, Dept Pharmacol, Hlth Sci Bldg,Box 357280, Seattle, WA 98195 USA
Univ Washington, Sch Med, Dept Pharmacol, Seattle, WA 98195 USA


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Label: Callicott-2005
Title: Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia
Journal: PROC NAT ACAD SCI USA, 102 (24): 8627-8632 JUN 14 2005
Citations: 151
Authors: Callicott, JH;Straub, RE;Pezawas, L;Egan, MF;Mattay, VS;Hariri, AR;Verchinski, BA;Meyer-Lindenberg, A;Balkissoon, R;Kolachana, B;Goldberg, TE;Weinberger, DR
Addresses:
Bldg 10,Ctr Dr,Room 4C-216,MSC 1364, Bethesda, MD 20892 USA
NIMH, Div Intramural Res, Clin Brain Disorders Branch, Genes Cognit & Psychosis Program,NIH, Bethesda, MD 20892 USA
US Dept HHS, Bethesda, MD 20892 USA


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Label: Millar-2005
Title: DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling
Journal: SCIENCE, 310 (5751): 1187-1191 NOV 18 2005
Citations: 146
Authors: Millar, JK;Pickard, BS;Mackie, S;James, R;Christie, S;Buchanan, SR;Malloy, MP;Chubb, JE;Huston, E;Baillie, GS;Thomson, PA;Hill, EV;Brandon, NJ;Rain, JC;Camargo, LM;Whiting, PJ;Houslay, MD;Blackwood, DHR;Muir, WJ;Porteous, DJ
Addresses:
Univ Edinburgh, Mol Med Ctr, Med Genet Sect, Edinburgh EH4 2XU, Midlothian, Scotland
Univ Edinburgh, Mol Med Ctr, Med Genet Sect, Edinburgh EH4 2XU, Midlothian, Scotland
Univ Glasgow, Inst Biomed & Life Sci, Div Biochem & Mol Biol, Mol Pharmacol Grp, Glasgow G12 8QQ, Lanark, Scotland
Merck Sharp & Dohme Ltd MSD, Neurosci Res Ctr, Harlow CM20 2QR, Essex, England
Hybrigen SA, F-75014 Paris, France
Univ Edinburgh, Royal Edinburgh Hosp, Div Psychiat, Edinburgh EH10 5HF, Midlothian, Scotland


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Label: Sin-2003
Title: Contemporary management of chronic obstructive pulmonary disease - Scientific review
Journal: JAMA-J AM MED ASSN, 290 (17): 2301-2312 NOV 5 2003
Citations: 134
Authors: Sin, DD;McAlister, FA;Man, SFP;Anthonisen, NR
Addresses:
Univ Alberta, Walter C Mackenzie Ctr 2E4 29, Div Pulm Med, Edmonton, AB T6G 2B7, Canada
Univ Alberta, Walter C Mackenzie Ctr 2E4 29, Div Pulm Med, Edmonton, AB T6G 2B7, Canada
Univ Alberta, Div Gen Med, Edmonton, AB T6G 2B7, Canada
Inst Hlth Econ, Edmonton, AB, Canada
Univ Manitoba, Dept Med, Winnipeg, MB, Canada


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Label: Schumacher-2004
Title: Examination of G72 and D-amino-acid oxidase as genetic risk factors for schizophrenia and bipolar affective disorder
Journal: MOL PSYCHIATR, 9 (2): 203-207 FEB 2004
Citations: 133
Authors: Schumacher, J;Jamra, RA;Freudenberg, J;Becker, T;Ohlraun, S;Otte, ACJ;Tullius, M;Kovalenko, S;Van Den Bogaert, A;Maier, W;Rietschel, M;Propping, P;Nothen, MM;Cichon, S
Addresses:
Univ Bonn, Inst Human Genet, Wilhelmstr 31, D-53111 Bonn, Germany
Univ Bonn, Inst Human Genet, D-53111 Bonn, Germany
Univ Bonn, Inst Med Biometry Informat & Epidemiol, D-5300 Bonn, Germany
Cent Inst Mental Hlth, D-6800 Mannheim, Germany
Univ Bonn, Dept Psychiat, D-5300 Bonn, Germany
Univ Antwerp, Dept Med Genet, B-2020 Antwerp, Belgium


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Label: Corfas-2004
Title: Neuregulin 1-erbB signaling and the molecular/cellular basis of schizophrenia
Journal: NAT NEUROSCI, 7 (6): 575-580 JUN 2004
Citations: 128
Authors: Corfas, G;Roy, K;Buxbaum, J
Addresses:
Childrens Hosp, Div Neurosci, 300 Longwood Ave, Boston, MA 02115 USA
Childrens Hosp, Div Neurosci, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Neurol, Boston, MA 02115 USA
CUNY Mt Sinai Sch Med, Dept Psychiat, New York, NY 10029 USA
CUNY Mt Sinai Sch Med, Dept Neurobiol, New York, NY 10029 USA


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Label: Lugnier-2006
Title: Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
Journal: PHARMACOL THER, 109 (3): 366-398 MAR 2006
Citations: 126
Authors: Lugnier, C
Addresses:
Univ Louis Pasteur Strasbourg 1, Fac Pharm, CNRS, UMR 7034, F-67401 Illkirch Graffenstaden, France
Univ Louis Pasteur Strasbourg 1, Fac Pharm, CNRS, UMR 7034, F-67401 Illkirch Graffenstaden, France


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Label: Lipworth-2005
Title: Phosphodiesterase-4 inhibitors for asthma and chronic obstructive pulmonary disease
Journal: LANCET, 365 (9454): 167-175 JAN 14 2005
Citations: 125
Authors: Lipworth, BJ
Addresses:
Univ Dundee, Ninewells Hosp & Med Sch, Dept Med & Therapeut, Asthma & Allergy Res Grp, Dundee DD1 9SY, Scotland
Univ Dundee, Ninewells Hosp & Med Sch, Dept Med & Therapeut, Asthma & Allergy Res Grp, Dundee DD1 9SY, Scotland


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Label: Houslay-2005
Title: Phosphodiesterase-4 as a therapeutic target
Journal: DRUG DISCOV TODAY, 10 (22): 1503-1519 NOV 15 2005
Citations: 123
Authors: Houslay, MD;Schafer, P;Zhang, KYJ
Addresses:
Univ Glasgow, Div Biochem & Mol Biol, IBLS, Wolfson Link Bldg,Univ Ave, Glasgow G12 8QQ, Lanark, Scotland
Univ Glasgow, Div Biochem & Mol Biol, IBLS, Glasgow G12 8QQ, Lanark, Scotland
Celgene, Drug Discovery Dept, Immunotherapeut Div, Summit, NJ 07901 USA
Plexxikon, Dept Biol Struct, Berkeley, CA 94710 USA


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Label: Niewoehner-2005
Title: Prevention of exacerbations of chronic obstructive pulmonary disease with tiotropium, a once-daily inhaled anticholinergic bronchodilator - A Randomized trial
Journal: ANN INTERN MED, 143 (5): 317-326 SEP 6 2005
Citations: 116
Authors: Niewoehner, DE;Rice, K;Cote, C;Paulson, D;Cooper, JAD;Korducki, L;Cassino, C;Kesten, S
Addresses:
Vet Adm Med Ctr, Pulm Sect 111N, 1 Vet Dr, Minneapolis, MN 55417 USA
Vet Adm Med Ctr, Pulm Sect 111N, Minneapolis, MN 55417 USA
Bay Pines Vet Affairs Med Ctr, Bay Pines, FL USA
Hunter Holmes McGuire Vet Affairs Med Ctr, Richmond, VA USA
Birmingham Vet Affairs Med Ctr, Birmingham, AL USA
Boehringer Ingelheim Pharmaceut Inc, Ridgefield, CT USA


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Label: Decramer-2005
Title: Effects of N-acetylcysteine on outcomes in chronic obstructive pulmonary disease (Bronchitis Randomized on NAC Cost-Utility Study, BRONCUS): a randomised placebo-controlled trial
Journal: LANCET, 365 (9470): 1552-1560 APR 30 2005
Citations: 115
Authors: Decramer, M;Rutten-van Molken, M;Dekhuijzen, PNR;Troosters, T;van Herwaarden, C;Pellegrino, R;van Schayck, CPO;Olivieri, D;Del Donno, M;De Backer, W;Lankhorst, I;Ardia, A
Addresses:
Katholieke Univ Leuven, Univ Hosp, Div Resp, Herestr 49, B-3000 Louvain, Belgium
Katholieke Univ Leuven, Univ Hosp, Div Resp, B-3000 Louvain, Belgium
Erasmus Med Ctr Rotterdam, Inst Med Technol, Rotterdam, Netherlands
Univ Med Ctr Nijmegen, Dept Pulm Dis, Nijmegen, Netherlands
Azienda Osped S Croce & Carle, Ctr Fysiopatol Resp & Studio Dispnea, Cuneo, Italy
Univ Parma, Dept Clin Sci, Univ Div Resp Dis, I-43100 Parma, Italy
Azienda Osped G Rummo, Unita Operat Pneumol, Benevento, Italy
Univ Hosp, Antwerp, Belgium
Zambon Grp, Bresso, Italy


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Label: Cannon-2005
Title: Association of DISC1/TRAX haplotypes with schizophrenia, reduced prefrontal gray matter, and impaired short- and long-term memory
Journal: ARCH GEN PSYCHIAT, 62 (11): 1205-1213 NOV 2005
Citations: 102
Authors: Cannon, TD;Hennah, W;van Erp, TGM;Thompson, PM;Lonnqvist, J;Huttunen, M;Gasperoni, T;Tuulio-Henriksson, A;Pirkola, T;Toga, AW;Kaprio, J;Mazziotta, J;Peltonen, L
Addresses:
Univ Calif Los Angeles, Dept Psychol, 1285 Franz Hall, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Dept Psychiat & Behav Sci, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Lab Neuroimaging, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, Ahmanson Lovelace Brain Mapping Ctr, Los Angeles, CA 90095 USA
Natl Publ Hlth Inst, Dept Mol Med, Helsinki, Finland
Natl Publ Hlth Inst, Dept Mental Hlth & Alcohol Res, Helsinki, Finland
Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland


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Label: Sin-2005
Title: Inhaled corticosteroids and mortality in chronic obstructive pulmonary disease
Journal: THORAX, 60 (12): 992-997 DEC 2005
Citations: 102
Authors: Sin, DD;Wu, L;Anderson, JA;Anthonisen, NR;Buist, AS;Burge, PS;Calverley, PM;Connett, JE;Lindmark, B;Pauwels, RA;Postma, DS;Soriano, JB;Szafranski, W;Vestbo, J
Addresses:
St Pauls Hosp, James Hogg iCAPTURE Ctr Cardiovasc & Pulm Res, 1081 Burrard St, Vancouver, BC V6Z 1Y6, Canada
St Pauls Hosp, James Hogg iCAPTURE Ctr Cardiovasc & Pulm Res, Vancouver, BC V6Z 1Y6, Canada
Univ British Columbia, Dept Med, Vancouver, BC V5Z 1M9, Canada
Univ Manitoba, Dept Med, Winnipeg, MB R3T 2N2, Canada
Oregon Hlth Sci Univ, Dept Med, Portland, OR 97201 USA
Birmingham Heartlands Hosp, NHS Trust, Birmingham B9 5ST, W Midlands, England
Univ Hosp Aintree, Liverpool, Merseyside, England
Univ Minnesota, Div Biostat, Sch Publ Hlth, Minneapolis, MN 55455 USA
AstraZeneca R&D, Lund, Sweden
State Univ Ghent Hosp, Dept Resp Dis, B-9000 Ghent, Belgium
Univ Groningen, Dept Pulm, NL-9700 AB Groningen, Netherlands
Fdn Caubcc Cimera, Palma de Mallorca, Balearic Isl, Spain
Voivodeship Specialist Hosp, Dept Lung Dis, Radom, Poland
Univ S Manchester Hosp, NHS Trust, Wythenshawe Hosp, Manchester M20 8LR, Lancs, England


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Label: Rabe-2005
Title: Roflumilast - an oral anti-inflammatory treatment for chronic obstructive pulmonary disease: a randomised controlled trial
Journal: LANCET, 366 (9485): 563-571 AUG 13 2005
Citations: 95
Authors: Rabe, KF;Bateman, ED;O'Donnell, D;Witte, S;Bredenbroker, D;Bethke, TD
Addresses:
Leiden Univ, Med Ctr, Dept Pulmonol, C3P,Albinusdreef 2, NL-2333 ZA Leiden, Netherlands
Leiden Univ, Med Ctr, Dept Pulmonol, NL-2333 ZA Leiden, Netherlands
Univ Cape Town, ZA-7925 Cape Town, South Africa
Kingston Gen Hosp, Kingston, ON K7L 2V7, Canada
ALTANA Pharma AG, Constance, Germany


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Label: Green-2005
Title: Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder
Journal: ARCH GEN PSYCHIAT, 62 (6): 642-648 JUN 2005
Citations: 92
Authors: Green, EK;Raybould, R;Macgregor, S;Gordon-Smith, K;Heron, J;Hyde, S;Grozeva, D;Hamshere, M;Williams, N;Owen, MJ;O'Donovan, MC;Jones, L;Jones, I;Kirov, G;Craddock, N
Addresses:
Univ Wales Coll Med, Dept Psychol Med, Henry Wellcomes Bldg Biomed Res,Heath Pk, Cardiff CF14 4XN, Wales
Univ Wales Coll Med, Dept Psychol Med, Cardiff CF14 4XN, Wales
Univ Wales Coll Med, Biostat & Bioinformat Unit, Cardiff, Wales
Univ Birmingham, Queen Elizabeth Psychiat Hosp, Dept Psychiat, Div Neurosci, Birmingham, W Midlands, England


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Label: Hahn-2006
Title: Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia
Journal: NATURE MED, 12 (7): 824-828 JUL 2006
Citations: 86
Authors: Hahn, CG;Wang, HY;Cho, DS;Talbot, K;Gur, RE;Berrettini, WH;Bakshi, K;Kamins, J;Borgmann-Winter, KE;Siegel, SJ;Gallop, RJ;Arnold, SE
Addresses:
Univ Penn, Dept Psychiat, Cellular & Mol Neuropathol Program, Ctr Neurobiol & Behav, Philadelphia, PA 19104 USA
Univ Penn, Dept Psychiat, Cellular & Mol Neuropathol Program, Ctr Neurobiol & Behav, Philadelphia, PA 19104 USA
CUNY, Sch Med, Dept Physiol & Pharmacol, New York, NY 10031 USA
W Chester Univ, Dept Math, Appl Stat Program, W Chester, PA 19380 USA


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Label: Law-2006
Title: Neuregulin 1 transcripts are differentially expressed in schizophrenia and regulated by 5 ' SNPs associated with the disease
Journal: PROC NAT ACAD SCI USA, 103 (17): 6747-6752 APR 25 2006
Citations: 86
Authors: Law, AJ;Lipska, BK;Weickert, CS;Hyde, TM;Straub, RE;Hashimoto, R;Harrison, PJ;Kleinman, JE;Weinberger, DR
Addresses:
Univ Oxford, Warneford Hosp, Dept Psychiat, Oxford OX3 7JX, England
Univ Oxford, Warneford Hosp, Dept Psychiat, Oxford OX3 7JX, England
NIMH, Clin Brain Disorders Branch, Intramural Res Program, NIH, Bethesda, MD 20892 USA


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Label: Aaron-2007
Title: Tiotropium in combination with placebo, salmeterol, or fluticasone-salmeterol for treatment of chronic obstructive pulmonary disease - A randomized trial
Journal: ANN INTERN MED, 146 (8): 545-U15 APR 17 2007
Citations: 79
Authors: Aaron, SD;Vandemheen, KL;Fergusson, D;Maltais, F;Bourbeau, J;Goldstein, R;Balter, M;O'Donnell, D;McIvor, A;Sharma, S;Bishop, G;Anthony, J;Cowie, R;Field, S;Hirsch, A;Hernandez, P;Rivington, R;Road, J;Hoffstein, V;Hodder, R;Marciniuk, D;McCormack, D;Fox, G;Cox, G;Prins, HB;Ford, G;Bleskie, D;Doucette, S;Mayers, I;Chapman, K;Zamel, N;FitzGerald, M
Addresses:
Ottawa Hosp, Gen Campus,501 Smyth Rd, Ottawa, ON K1H 8L6, Canada
Ottawa Hosp, Ottawa, ON K1H 8L6, Canada
Univ Ottawa, Hlth Res Inst, Ottawa, ON K1N 6N5, Canada
Univ Toronto, Toronto, ON, Canada
McMaster Univ, Hamilton, ON L8S 4L8, Canada
Queens Univ, Kingston, ON K7L 3N6, Canada
Scarborough Centenary Hosp, Scarborough, ON, Canada
Univ Western Ontario, London, ON N6A 3K7, Canada
St Lawrence Med Clin, Morrisburg, ON, Canada
Univ British Columbia, Vancouver, BC V5Z 1M9, Canada
Univ Laval, Hop Laval, Ctr Rech, Quebec City, PQ G1K 7P4, Canada
McGill Univ, Halifax, NS, Canada
Univ Manitoba, Winnipeg, MB R3T 2N2, Canada
Univ New Brunswick, St John, NB E2L 4L5, Canada
Univ Saskatchewan, Saskatoon, SK S7N 0W0, Canada
Univ Calgary, Calgary, AB T2N 1N4, Canada
Univ Alberta, Edmonton, AB T6G 2M7, Canada
Mem Univ Newfoundland, St John, NF, Canada
Woolcock Inst Med Res, Sydney, NSW, Australia


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Label: Harrison-2006
Title: Neuregulin 1 and schizophrenia: Genetics, gene expression, and neurobiology
Journal: BIOL PSYCHIAT, 60 (2): 132-140 JUL 15 2006
Citations: 77
Authors: Harrison, PJ;Law, AJ
Addresses:
Univ Oxford, Dept Psychiat, Warneford Hosp, Oxford OX3 7JX, England
Univ Oxford, Dept Psychiat, Warneford Hosp, Oxford OX3 7JX, England


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Label: Conti-2007
Title: Biochemistry and physiology of cyclic nucleotide Phosphocliesterases: Essential components in cyclic nucleotide signaling
Journal: ANNU REV BIOCHEM, 76: 481-511 2007
Citations: 74
Authors: Conti, M;Beavo, J
Addresses:
Stanford Univ, Sch Med, Dept Obstet & Gynecol, Div Reprod Biol, Stanford, CA 94305 USA
Stanford Univ, Sch Med, Dept Obstet & Gynecol, Div Reprod Biol, Stanford, CA 94305 USA
Univ Washington, Dept Pharmacol, Seattle, WA 98195 USA


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Label: Barnes-2006
Title: Antiinflammatory effects of salmeterol/fluticasone propionate in chronic obstructive lung disease
Journal: AMER J RESPIR CRIT CARE MED, 173 (7): 736-743 APR 1 2006
Citations: 65
Authors: Barnes, NC;Qiu, YS;Pavord, ID;Parker, D;Davis, PA;Zhu, L;Johnson, M;Thomson, NC;Jeffery, PK;SCO30005 Study Grp
Addresses:
Royal Brompton Hosp, Sydney St, London SW3 6NP, England
Univ London Imperial Coll Sci Technol & Med, Lung Pathol Unit, Royal Brompton Hosp, London, England
London Chest Hosp, Dept Resp Med, London E2 9JX, England
Glenfield Gen Hosp, Inst Lung Hlth, Leicester LE3 9QP, Leics, England
GlaxoSmithKline Res & Dev Ltd, Greenford, Middx, England
Univ Glasgow, Dept Resp Med, Glasgow, Lanark, Scotland


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Label: Wedzicha-2008
Title: The prevention of chronic obstructive pulmonary disease exacerbations by salmeterol/fluticasone propionate or tiotropium bromide
Journal: AMER J RESPIR CRIT CARE MED, 177 (1): 19-26 JAN 1 2008
Citations: 65
Authors: Wedzicha, JA;Calverley, PMA;Seemungal, TA;Hagan, G;Ansari, Z;Stockley, RA;INSPIRE Investigators
Addresses:
Univ Coll London, Royal Free & Univ Coll, Acad Unit Resp Med, Sch Med, Rowland Hill St, London, England
Univ Coll London, Royal Free & Univ Coll, Acad Unit Resp Med, Sch Med, London, England
Aintree Univ Hosp NHS Fdn Trust, Dept Med, Liverpool, Merseyside, England
Univ W Indies, Dept Clin Med Sci, Mt Hope, Trinid & Tobago
GlaxoSmithKline Inc, Resp Med Ctr, Greenford, Middx, England
Univ Hosp Birmingham, Dept Med, NHS Fdn Trust, Birmingham, W Midlands, England


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Label: Hamshere-2005
Title: Genomewide linkage scan in Schizoaffective disorder - Significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13
Journal: ARCH GEN PSYCHIAT, 62 (10): 1081-1088 OCT 2005
Citations: 63
Authors: Hamshere, ML;Bennett, P;Williams, N;Segurado, R;Cardno, A;Norton, N;Lambert, D;Williams, H;Kirov, G;Corvin, A;Holmans, P;Jones, I;Gill, M;O'Donovan, MC;Owen, MJ;Craddock, N
Addresses:
Cardiff Univ, Dept Psychol Med, Wales Sch Med, Henry Wellcome Bldg,Heath Pk, Cardiff, Wales
Cardiff Univ, Dept Psychol Med, Wales Sch Med, Cardiff, Wales
Cardiff Univ, Biostat & Bioinformat Unit, Sch Med, Cardiff, Wales
Univ Birmingham, Queen Elizabeth Psychiat Hosp, Div Neurosci, Birmingham, W Midlands, England
Trinity Coll Dublin, Dept Psychiat, Dublin, Ireland
Trinity Coll Dublin, Dept Genet, Dublin, Ireland


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Label: Clapcote-2007
Title: Behavioral phenotypes of Disc1 missense mutations in mice
Journal: NEURON, 54 (3): 387-402 MAY 3 2007
Citations: 61
Authors: Clapcote, SJ;Lipina, TV;Millar, JK;Mackie, S;Christie, S;Ogawa, F;Lerch, JP;Trimble, K;Uchiyama, M;Sakuraba, Y;Kaneda, H;Shiroishi, T;Houslay, MD;Henkelman, RM;Sled, JG;Gondo, Y;Porteous, DJ;Roder, JC
Addresses:
Mt Sinai Hosp, Samuel Lunenfeld Res Inst, 600 Univ Ave, Toronto, ON M5G 1X5, Canada
Mt Sinai Hosp, Samuel Lunenfeld Res Inst, Toronto, ON M5G 1X5, Canada
Univ Edinburgh, Med Genet Sect, Ctr Mol Med, Edinburgh EH4 2XU, Midlothian, Scotland
Hosp Sick Children, Mouse Imaging Ctr, Toronto, ON M5G 1X8, Canada
Hosp Sick Children, Auditory Sci Lab, Toronto, ON M5G 1X8, Canada
RIKEN, Genom Sci Ctr, Tsurumi Ku, Yokohama, Kanagawa 2300045, Japan
Univ Glasgow, IBLS, Mol Pharmacol Grp, Div Biochem & Mol Biol, Glasgow G12 8QQ, Lanark, Scotland
Univ Toronto, Dept Med Biophys, Toronto, ON M5S 1A1, Canada
Univ Toronto, Dept Mol & Med Genet, Toronto, ON M5S 1A1, Canada


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Label: Kardos-2007
Title: Impact of salmeterol/fluticasone propionate versus salmeterol on exacerbations in severe chronic obstructive pulmonary disease
Journal: AMER J RESPIR CRIT CARE MED, 175 (2): 144-149 JAN 15 2007
Citations: 61
Authors: Kardos, P;Wencker, M;Glaab, T;Vogelmeier, C
Addresses:
Maingau Hosp, Grp Practice, Scheffelstr 2, D-60318 Frankfurt, Germany
Maingau Hosp, Grp Practice, D-60318 Frankfurt, Germany
Maingau Hosp, Ctr Resp & Sleep Med, D-60318 Frankfurt, Germany
GlaxoSmithKline Inc, Therapeut Area Resp, Munich, Germany
Univ Marburg, Dept Resp Med, D-35032 Marburg, Germany


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Label: Tashkin-2008
Title: A 4-year trial of tiotropium in chronic obstructive pulmonary disease
Journal: N ENGL J MED, 359 (15): 1543-1554 OCT 9 2008
Citations: 61
Authors: Tashkin, DP;Celli, B;Senn, S;Burkhart, D;Kesten, S;Menjoge, S;Decramer, M;UPLIFT Study Investigators
Addresses:
Univ Calif Los Angeles, David Geffen Sch Med, 10833 Le Conte Ave, Los Angeles, CA 90095 USA
Univ Calif Los Angeles, David Geffen Sch Med, Los Angeles, CA 90095 USA
Caritas St Elizabeths Med Ctr, Boston, MA USA
Univ Glasgow, Glasgow, Lanark, Scotland
Boehringer Ingelheim Pharmaceut Inc, Ridgefield, CT 06877 USA
Katholieke Univ Leuven, Louvain, Belgium


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Label: Omori-2007
Title: Overview of PDEs and their regulation
Journal: CIRC RES, 100 (3): 309-327 FEB 16 2007
Citations: 60
Authors: Omori, K;Kotera, J
Addresses:
Tanabe Seiyaku Co Ltd, Discovery Res Labs, 2-50 Kawagishi,2 Chome, Toda, Saitama 3358505, Japan
Tanabe Seiyaku Co Ltd, Discovery Res Labs, Toda, Saitama 3358505, Japan


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Label: Williams-2006
Title: Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder
Journal: ARCH GEN PSYCHIAT, 63 (4): 366-373 APR 2006
Citations: 53
Authors: Williams, NM;Green, EK;Macgregor, S;Dwyer, S;Norton, N;Williams, H;Raybould, R;Grozeva, D;Hamshere, M;Zammit, S;Jones, L;Cardno, A;Kirov, G;Jones, I;O'Donovan, MC;Owen, MJ;Craddock, N
Addresses:
Univ Cardiff Wales, Wales Sch Med, Dept Psychol Med, Henry Wellcome Bldg,Hlth Pk, Cardiff CF14 4XN, Wales
Univ Cardiff Wales, Wales Sch Med, Dept Psychol Med, Cardiff CF14 4XN, Wales
Univ Cardiff Wales, Wales Sch Med, Biostat & Bioinformat Unit, Cardiff CF14 4XN, Wales
Univ Birmingham, Queen Elizabeth Psychiat Hosp, Div Neurosci, Birmingham, W Midlands, England


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Label: Li-2007
Title: The neuregulin-1 receptor ErbB4 controls Glutamatergic synapse maturation and plasticity
Journal: NEURON, 54 (4): 583-597 MAY 24 2007
Citations: 47
Authors: Li, B;Woo, RS;Mei, L;Malinow, R
Addresses:
Cold Spring Harbor Lab, POB 100, Cold Spring Harbor, NY 11724 USA
Cold Spring Harbor Lab, Cold Spring Harbor, NY 11724 USA
Med Coll Georgia, Inst Mol Med & Genet, Program Dev Neurobiol, Augusta, GA 30912 USA
Med Coll Georgia, Inst Mol Med & Genet, Dept Neurol, Augusta, GA 30912 USA


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Label: McClellan-2007
Title: Schizophrenia: a common disease caused by multiple rare alleles
Journal: BRIT J PSYCHIAT, 190: 194-199 MAR 2007
Citations: 47
Authors: McClellan, JM;Susser, E;King, MC
Addresses:
Univ Washington, Dept Psychiat, Box 356560, Seattle, WA 98195 USA
Univ Washington, Dept Psychiat, Seattle, WA 98195 USA
Columbia Univ, Dept Epidemiol, Mailman Sch Publ Hlth, Dept Psychiat, New York, NY USA
New York State Psychiat Inst & Hosp, New York, NY 10032 USA
Univ Washington, Dept Genome Sci, Seattle, WA 98195 USA
Univ Washington, Dept Med Med Genet, Seattle, WA 98195 USA


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Label: Sanders-2008
Title: No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: Implications for psychiatric genetics
Journal: AMER J PSYCHIAT, 165 (4): 497-506 APR 2008
Citations: 45
Authors: Sanders, AR;Duan, J;Levinson, DF;Shi, J;He, D;Hou, C;Burrell, GJ;Rice, JP;Nertney, DA;Olincy, A;Rozic, P;Vinogradov, S;Buccola, NG;Mowry, BJ;Freedman, R;Amin, F;Black, DW;Silverman, JM;Byerley, WF;Crowe, RR;Cloninger, CR;Martinez, M;Gejman, PV
Addresses:
Evanston Northwestern Healthcare Res Inst, 1001 Univ Pl, Evanston, IL 60201 USA
Northwestern Univ, Ctr Psychiat Genet, Dept Psychiat & Behav Sci, Evanston Northwestern Healthcare & Feinberg Sch M, Evanston, IL USA
Stanford Univ, Sch Med, Dept Psychiat & Behav Sci, Palo Alto, CA 94304 USA
Washington Univ, Dept Psychiat, St Louis, MO USA
Washington Univ, Dept Genet, St Louis, MO USA
Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia
Queensland Inst Med Res, Brisbane, Qld, Australia
Univ Colorado, Hlth Sci Ctr, Dept Psychiat, Denver, CO 80262 USA
Louisiana State Univ, Hlth Sci Ctr, Dept Psychiat, New Orleans, LA USA
Emory Univ, Atlanta Vet Affairs Med Ctr, Atlanta, GA 30322 USA
Emory Univ, Dept Psychiat & Behav Sci, Atlanta, GA 30322 USA
Univ Iowa, Coll Med, Mental Hlth Clin Res Ctr, Iowa City, IA USA
Univ Iowa, Coll Med, Dept Psychiat, Iowa City, IA 52242 USA
Mt Sinai Sch Med, Dept Psychiat, New York, NY USA
Univ Calif San Francisco, Dept Psychiat, San Francisco, CA 94143 USA
Fac Med Toulouse, INSERM, Dept Genet, U563, F-31073 Toulouse, France


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Label: Crow-2007
Title: How and why genetic linkage has not solved the problem of psychosis: Review and hypothesis
Journal: AMER J PSYCHIAT, 164 (1): 13-21 JAN 2007
Citations: 41
Authors: Crow, TJ
Addresses:
Warneford Hosp, SANE POWIC Ctr, Oxford OX3 7JX, England
SANE Prince Wales Ctr Res Schizophrenia & Depress, Dept Psychiat, Oxford, England


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Label: Celli-2008
Title: Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease - Results from the TORCH study
Journal: AMER J RESPIR CRIT CARE MED, 178 (4): 332-338 AUG 15 2008
Citations: 36
Authors: Celli, BR;Thomas, NE;Anderson, JA;Ferguson, GT;Jenkins, CR;Jones, PW;Vestbo, J;Knobil, K;Yates, JC;Calverley, PMA
Addresses:
Tufts Univ, Sch Med, Div Pulm & Crit Care, Caritas St Elizabeths Med Ctr, Brighton, MA 02135 USA
Tufts Univ, Sch Med, Div Pulm & Crit Care, Caritas St Elizabeths Med Ctr, Brighton, MA 02135 USA
GlaxoSmithKline Inc, Resp Med Ctr, Greenford, Middx, England
Inst SE Michigan, Livonia, MI USA
Woolcock Inst Med Res, Camperdown, NSW, Australia
St Georges Univ London, Div Cardiac & Vasc Sci, London, England
Univ Copenhagen, Hvidovre Hosp, DK-2650 Hvidovre, Denmark
Wythenshawe Hosp, N W Lung Ctr, Manchester M23 9LT, Lancs, England
GlaxoSmithKline Inc, Resp Med Ctr, Res Triangle Pk, NC USA
Aintree Univ Hosp NHS Fdn Trust, Dept Med, Liverpool L9 7AL, Merseyside, England


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Label: Singh-2008
Title: Inhaled anticholinergics and risk of major adverse cardiovascular events in patients with chronic obstructive pulmonary disease - A systematic review and meta-analysis
Journal: JAMA-J AM MED ASSN, 300 (12): 1439-1450 SEP 24 2008
Citations: 32
Authors: Singh, S;Loke, YK;Furberg, CD
Addresses:
Wake Forest Univ, Sch Med, Dept Med, 1 Med Ctr Blvd, Winston Salem, NC 27157 USA
Wake Forest Univ, Sch Med, Dept Med, Winston Salem, NC 27157 USA
Wake Forest Univ, Sch Med, Div Publ Hlth Sci, Winston Salem, NC 27157 USA
Univ E Anglia, Sch Med Hlth Policy & Practice, Norwich NR4 7TJ, Norfolk, England


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Label: Craddock-2007
Title: Phenotypic and genetic complexity of psychosis - Invited commentary on ... Schizophrenia: a common disease caused by multiple rare alleles
Journal: BRIT J PSYCHIAT, 190: 200-203 MAR 2007
Citations: 30
Authors: Craddock, N;O'Donovan, MC;Owen, MJ
Addresses:
Univ Cardiff Wales, Wales Sch Med, Dept Psychol Med, Henry Wellcome Bldg,Heath Pk, Cardiff CF14 4XN, Wales
Univ Cardiff Wales, Wales Sch Med, Dept Psychol Med, Cardiff CF14 4XN, Wales


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Label: Mei-2008
Title: Neuregulin 1 in neural development, synaptic plasticity and schizophrenia
Journal: NAT REV NEUROSCI, 9 (6): 437-452 JUN 2008
Citations: 24
Authors: Mei, L;Xiong, WC
Addresses:
Med Coll Georgia, Program Dev Neurobiol, Inst Mol Med & Genet, Dept Neurol, Augusta, GA 30912 USA
Med Coll Georgia, Program Dev Neurobiol, Inst Mol Med & Genet, Dept Neurol, Augusta, GA 30912 USA


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Label: Suissa-2008
Title: Methodological issues in therapeutic trials of COPD
Journal: EUR RESP J, 31 (5): 927-933 MAY 2008
Citations: 22
Authors: Suissa, S;Ernst, P;Vandemheen, KL;Aaron, SD
Addresses:
Royal Victoria Hosp, Div Clin Epidemiol, 687 Pine Ave W,Ross 4 29, Montreal, PQ H3A 1A1, Canada
McGill Univ Hlth Ctr, McGill Pharmacoepidemiol Res Unit, Montreal, PQ, Canada
McGill Univ, Dept Epidemiol & Biostat, Montreal, PQ, Canada
McGill Univ, Dept Med, Montreal, PQ, Canada
Univ Ottawa, Ottawa Hlth Res Inst, Ottawa, ON, Canada


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Label: Shi-2008
Title: Allelic association of G72/G30 with schizophrenia and bipolar disorder: A comprehensive meta-analysis
Journal: SCHIZOPHR RES, 98 (1-3): 89-97 JAN 2008
Citations: 19
Authors: Shi, JJ;Badner, JA;Gershon, ES;Liu, CY
Addresses:
Univ Chicago, Dept Psychiat, Chicago, IL 60637 USA
Univ Chicago, Dept Psychiat, Chicago, IL 60637 USA


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Label: Zheng-2008
Title: Effect of carbocisteine on acute exacerbation of chronic obstructive pulmonary disease (PEACE Study): a randomised placebo-controlled study
Journal: LANCET, 371 (9629): 2013-2018 JUN 14 2008
Citations: 19
Authors: Zheng, JP;Kang, J;Huang, SG;Chen, P;Yao, WZ;Yang, L;Bai, CX;Wang, CZ;Wang, C;Chen, BY;Shi, Y;Liu, CT;Chen, P;Li, Q;Wang, ZS;Huang, YJ;Luo, ZY;Chen, FP;Yuan, JZ;Yuan, BT;Qian, HP;Zhi, RC;Zhong, NS
Addresses:
First Affiliated Hosp, Guangzhou Med Coll, State Key Lab Resp Dis, Guangzhou Inst Resp Dis, Guangzhou 510120, Peoples R China
First Affiliated Hosp, Guangzhou Med Coll, State Key Lab Resp Dis, Guangzhou Inst Resp Dis, Guangzhou 510120, Peoples R China
China Med Univ, Affiliated Hosp 1, Shenyang, Peoples R China
Shanghai Jiao Tong Univ, Sch Med, Ruijing Hosp, Shanghai 200030, Peoples R China
Shenyang PLA Gen Hosp, Shenyang, Peoples R China
Peking Univ, Hosp 3, Beijing 100871, Peoples R China
Xian Jiaotong Univ, Affiliated Hosp 1, Xian 710049, Peoples R China
Fudan Univ, Zhongshan Hosp, Shanghai 200433, Peoples R China
Xin Qiao Hosp, Chongqing, Peoples R China
Chao Yang Hosp, Beijing, Peoples R China
Tianjin Gen Hosp, Tianjin, Peoples R China
Nanjing PLA Gen Hosp, Nanjing, Peoples R China
Huaxi Hosp, Chengdu, Peoples R China
Second Xiangya Hosp, Changsha, Peoples R China
Changhai Hosp, Shanghai, Peoples R China
Dalian Med Univ, Affiliated Hosp 2, Dalian, Peoples R China
Hainan Prov Hosp, Haikou, Peoples R China
First Municipal Hosp, Foshan, Peoples R China
Second Affiliated Hosp, Guangzhou Med Coll, Guangzhou, Peoples R China
Red Cross Hosp, Guangzhou, Peoples R China
Second Municipal Hosp, Shenzhen, Peoples R China
Xinhai Hosp, Guangzhou, Peoples R China
Panyu Hosp, Guangzhou, Peoples R China


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Label: Munafo-2008
Title: Neuregulin 1 genotype and schizophrenia
Journal: SCHIZOPHRENIA BULL, 34 (1): 9-12 JAN 2008
Citations: 17
Authors: Munafo, MR;Attwood, AS;Flint, J
Addresses:
Univ Bristol, Dept Expt Psychol, 12A Priory Rd, Bristol BS8 1TU, Avon, England
Univ Bristol, Dept Expt Psychol, Bristol BS8 1TU, Avon, England
Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford OX3 7BN, England


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KEYWORDS: CHRONIC OBSTRUCTIVE PULMONARY DISEASE (BRONCHITIS RANDOMIZED; CHRONIC OBSTRUCTIVE PULMONARY DISEASE EXACERBATIONS; CHRONIC OBSTRUCTIVE PULMONARY DISEASE (PEACE STUDY); SEVERE CHRONIC OBSTRUCTIVE PULMONARY DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE.
[9048: (2003-2009_4) (CLI/PSY; Chronic Obstructive Pulmonary Disease [COPD])



Special Topics : Chronic Obstructive Pulmonary Disease (COPD) : Research Front Map of Chronic Obstructive Pulmonary Disease