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SPECIAL TOPICS

Diabetes - May 2009

Research Front Maps

Research front maps are diagrammatic representations of the core papers comprising each front. They are selected from the current Research Front set that are relevant to the featured special topic. The title for this Research Front Map is "INSULIN TREATMENT OF TYPE 2 DIABETES," containing 17 core papers. Source dates: 1999-February 28, 2009 (first bimonthly period 2009).

Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The solid lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together); weaker links are indicated by dashed lines. Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in pink. Annotations may have been added to this map which represent the main research themes. These appear as labels attached to specific regions on the maps.

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Monnier-2003 Riddle-2003 Hermansen-2004 Heise-2004 Haak-2005 Janka-2005 Raskin-2005 Rosenstock-2005 Garber-2006 Yki-Jarvinen-2006 Rosenstock-2006 Hermansen-2006 Janka-2007 Klein-2007 Holman-2007 Rosenstock-2008 Bretzel-2008

INSULIN TREATMENT OF TYPE 2 DIABETES


 Core Papers 


Label: Riddle-2003
Title: The treat-to-target trial - Randomized addition of glargine or human NPH insulin to oral therapy of type 2 diabetic patients
Journal: DIABETES CARE, 26 (11): 3080-3086 NOV 2003
Citations: 309
Authors: Riddle, MC;Rosenstock, J;Gerich, J;Insulin Glargine 4002 Study Invest
Addresses:
Oregon Hlth & Sci Univ, Sect Diabet L 345, 3181 SW Sam Jackson, Portland, OR 97201 USA
Oregon Hlth & Sci Univ, Sect Diabet L 345, Portland, OR 97201 USA
Dallas Diabet & Endocrine Ctr, Dallas, TX USA
Univ Rochester, Ctr Med, Rochester, NY USA


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Label: Monnier-2003
Title: Contributions of fasting and postprandial plasma glucose increments to the overall diurnal hyperglycemia of type 2 diabetic patients - Variations with increasing levels of HbA(1c)
Journal: DIABETES CARE, 26 (3): 881-885 MAR 2003
Citations: 246
Authors: Monnier, L;Lapinski, H;Colette, C
Addresses:
Lapeyronie Hosp, Dept Metab, F-34295 Montpellier 5, France
Lapeyronie Hosp, Dept Metab, F-34295 Montpellier 5, France
Univ Inst Clin Res, Montpellier, France


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Label: Raskin-2005
Title: Initiating insulin therapy in type 2 diabetes - A comparison of biphasic and basal insulin analogs
Journal: DIABETES CARE, 28 (2): 260-265 FEB 2005
Citations: 164
Authors: Raskin, P;Hu, P;Allen, E;Bode, B;Hollander, P;Garber, A;Lewin, A;Gabbay, RA;INITIATE Study Grp
Addresses:
Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75390 USA
Univ Texas, SW Med Ctr, Dept Internal Med, Dallas, TX 75390 USA
Novo Nordisk, Princeton, NJ USA
Baylor Univ, Med Ctr, Dallas, TX USA
Natl Res Inst, Los Angeles, CA USA
Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Hershey, PA 17033 USA
Atlanta Diabet Assoc, Atlanta, GA USA
Baylor Coll Med, Houston, TX 77030 USA


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Label: Heise-2004
Title: Lower within-subject variability of insulin detemir in comparison to NPH insulin and insulin glargine in people with type 1 diabetes
Journal: DIABETES, 53 (6): 1614-1620 JUN 2004
Citations: 137
Authors: Heise, T;Nosek, L;Ronn, BB;Endahl, L;Heinemann, L;Kapitza, C;Draeger, E
Addresses:
Profil Inst Stoffwechselforsch, Hellersbergstr 9, D-41460 Neuss, Germany
Profil Inst Stoffwechselforsch, D-41460 Neuss, Germany
Novo Nordisk, Bagsvaerd, Denmark


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Label: Hermansen-2004
Title: Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with Type 1 diabetes
Journal: DIABETOLOGIA, 47 (4): 622-629 APR 2004
Citations: 107
Authors: Hermansen, K;Fontaine, P;Kukolja, KK;Peterkova, V;Leth, G;Gall, MA
Addresses:
Aarhus Univ Hosp, Dept Endocrinol & Metab, DK-8000 Aarhus C, Denmark
Aarhus Univ Hosp, Dept Endocrinol & Metab, DK-8000 Aarhus C, Denmark
Univ Hosp, Dept Diabetol, Lille, France
State Endocrinol Res Ctr, Moscow, Russia
Novo Nordisk AS, DK-2880 Bagsvaerd, Denmark


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Label: Janka-2005
Title: Comparison of basal insulin added to oral agents versus twice-daily premixed insulin as initial insulin therapy for type 2 diabetes
Journal: DIABETES CARE, 28 (2): 254-259 FEB 2005
Citations: 102
Authors: Janka, HU;Kliebe-Frisch, C;Plewe, G;Schweitzer, MA;Riddle, MC;Yki-Jarvinen, H
Addresses:
Zent Krankenhaus Bremen Nord, Med Abt 2, Hammersbecker Str 228, D-28755 Bremen, Germany
Zent Krankenhaus Bremen Nord, Med Abt 2, D-28755 Bremen, Germany
Oregon Hlth Sci Univ, Div Endocrinol Diabet & Clin Nutr, Portland, OR 97201 USA
Univ Helsinki, Dept Med, Helsinki, Finland
Aventis Pharma Deutschland, Bad Soden, Germany


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Label: Hermansen-2006
Title: A 26-week, randomized, parallel, treat-to-target trial comparing insulin detemir with NPH insulin as add-on therapy to oral glucose-lowering drugs in insulin-naive people with type 2 diabetes
Journal: DIABETES CARE, 29 (6): 1269-1274 JUN 2006
Citations: 101
Authors: Hermansen, K;Davies, M;Derezinski, T;Ravn, GM;Clauson, P;Home, P;Levemir Treat-To-Target Study Grp
Addresses:
Aarhus Univ Hosp, Aarhus Sygehus THG, Dept Endocrinol & Metab, DK-8000 Aarhus C, Denmark
Aarhus Univ Hosp, Aarhus Sygehus THG, Dept Endocrinol & Metab, DK-8000 Aarhus C, Denmark
Univ Hosp Leicester, Leicester Royal Infirm, Leicester, Leics, England
NZOZ Eskulap, Out Patient Clin, Gniewkowo, Poland
Novo Nordisk, Bagsvaerd, Denmark
Univ Newcastle Upon Tyne, Sch Med Sci Diabet, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England


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Label: Haak-2005
Title: Lower within-subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes
Journal: DIABETES OBES METAB, 7 (1): 56-64 JAN 2005
Citations: 80
Authors: Haak, T;Tiengo, A;Draeger, E;Suntum, M;Waldhausl, W
Addresses:
Diabet Acad Mergentheim, Res Inst, Theodor Klotzbucher Str 12, D-97980 Bad Mergentheim, Germany
Diabet Acad Mergentheim, Res Inst, D-97980 Bad Mergentheim, Germany
Univ Padua, Sch Med, Dept Clin & Expt Med, Padua, Italy
Novo Nordisk AS, Gladsaxe, Denmark
Med Unv Vienna, Dept Med 3, Vienna, Austria


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Label: Yki-Jarvinen-2006
Title: Insulin glargine or NPH combined with metformin in type 2 diabetes: the LANMET study
Journal: DIABETOLOGIA, 49 (3): 442-451 MAR 2006
Citations: 70
Authors: Yki-Jarvinen, H;Kauppinen-Makelin, R;Tiikkainen, M;Vahatalo, M;Virtamo, H;Nikkila, K;Tulokas, T;Hulme, S;Hardy, K;McNulty, S;Hanninen, J;Levanen, H;Lahdenpera, S;Lehtonen, R;Ryysy, L
Addresses:
Univ Helsinki, Dept Med, POB 340, FIN-00029 Helsinki, Finland
Univ Helsinki, Dept Med, FIN-00029 Helsinki, Finland
Jorvi Hosp, SF-02740 Espoo, Finland
City Turku Hlth Ctr, Turku, Finland
Lappi Cent Hosp, Rovaniemi, Finland
Whiston Hosp, Prescot, England
Mikkeli Hlth Ctr, Mikkeli, Finland
Sanofi Aventis, Helsinki, Finland
Kymenlaakso Cent Hosp, Kotka, Finland


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Label: Rosenstock-2005
Title: Reduced hypoglycemia risk with insulin glargine - A metaanalysis comparing insulin glargine with human NPH insulin in type 2 diabetes
Journal: DIABETES CARE, 28 (4): 950-955 APR 2005
Citations: 69
Authors: Rosenstock, J;Dailey, G;Massi-Benedetti, M;Fritsche, A;Lin, ZN;Salzman, A
Addresses:
Dallas Diabet & Endocrine Ctr, 7777 Forest Ln,Suite C-618, Dallas, TX 75230 USA
Dallas Diabet & Endocrine Ctr, Dallas, TX 75230 USA
Univ Calif San Diego, Dept Med, La Jolla, CA 92093 USA
Univ Perugia, Dept Med, I-06100 Perugia, Italy
Med Univ Klin, Tubingen, Germany
Aventis Pharm, Bridgewater, NJ USA


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Label: Holman-2007
Title: Addition of biphasic, prandial, or basal insulin to oral therapy in type 2 diabetes
Journal: N ENGL J MED, 357 (17): 1716-1730 OCT 25 2007
Citations: 51
Authors: Holman, RR;Thorne, KI;Farmer, AJ;Davies, MJ;Keenan, JF;Paul, S;Levy, JC;4-T Study Grp
Addresses:
Churchill Hosp, Oxford Ctr Diabet Endocrinol & Metab, Diabet Trials Unit, Oxford OX3 7LJ, England
Univ Oxford, Oxford Ctr Diabet Endocrinol & Metab, Diabet Trials Unit, Oxford, England
Univ Oxford, Dept Primary Hlth Care, Oxford, England
Univ Leicester, Dept Cardiovasc Sci, Leicester, Leics, England


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Label: Rosenstock-2006
Title: Triple therapy in type 2 diabetes - Insulin glargine or rosiglitazone added to combmiation therapy of sulfonylurea plus metformin in insulin-naive patients
Journal: DIABETES CARE, 29 (3): 554-559 MAR 2006
Citations: 49
Authors: Rosenstock, J;Sugimoto, D;Strange, P;Stewart, JA;Soltes-Rak, E;Dailey, G;Insulin Glargine 4014 Study Invest
Addresses:
Dallas Diabet & Endocrine Ctr Med City, 7777 Forest Ln,C-618, Dallas, TX 75230 USA
Dallas Diabet & Endocrine Ctr Med City, Dallas, TX 75230 USA
Cedar Crosse Res Ctr, Chicago, IL USA
Aventis Pharmaceut, Bridgewater, NJ USA
Aventis Pharma, Quebec City, PQ, Canada
Diabet & Endocrinol Scripps Clin, La Jolla, CA USA


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Label: Garber-2006
Title: Attainment of glycaemic goals in type 2 diabetes with once-, twice-, or thrice-daily dosing with biphasic insulin aspart 70/30 (The 1-2-3 study)
Journal: DIABETES OBES METAB, 8 (1): 58-66 JAN 2006
Citations: 48
Authors: Garber, AJ;Wahlen, J;Wahl, T;Bressler, P;Braceras, R;Allen, E;Jain, R
Addresses:
Baylor Coll Med, BCM Fac Ctr, 1709 Dryden Rd,Suite 1000, Houston, TX 77030 USA
Baylor Coll Med, BCM Fac Ctr, Houston, TX 77030 USA
Endocrine Res Specialists, Ogden, UT USA
Internal Med Assoc Res Ctr, Omaha, NE USA
Endocrine & Diabet Assoc, Dallas, TX USA
Novo Nordisk AS, Princeton, NJ USA
Adv Healthcare, Milwaukee Med Clin, Milwaukee, WI USA


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Label: Klein-2007
Title: Albumin-bound basal insulin analogues (insulin detemir and NN344): comparable time-action profiles but less variability than insulin glargine in type 2 diabetes
Journal: DIABETES OBES METAB, 9 (3): 290-299 MAY 2007
Citations: 32
Authors: Klein, O;Lynge, J;Endahl, L;Damholt, B;Nosek, L;Heise, T
Addresses:
Profil Inst Stoffwechselforsch GmbH, Hellersbergstr 9, D-41460 Neuss, Germany
Profil Inst Stoffwechselforsch GmbH, D-41460 Neuss, Germany
Novo Nordisk AS, DK-2880 Bagsvaerd, Denmark


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Label: Bretzel-2008
Title: Once-daily basal insulin glargine versus thrice-daily prandial insulin lispro in people with type 2 diabetes on oral hypoglycaemic agents (APOLLO): an open randomised controlled trial
Journal: LANCET, 371 (9618): 1073-1084 MAR-APR 2008
Citations: 20
Authors: Bretzel, RG;Nuber, U;Landgraf, W;Owens, DR;Bradley, C;Linn, T
Addresses:
Univ Giessen, Med Klin & Poliklin 3, Rodthohl 6, D-35392 Giessen, Germany
Univ Giessen, Med Klin & Poliklin 3, D-35392 Giessen, Germany
Sanofi Aventis Deutschland GmbH, Med Affairs, Berlin, Germany
Llandough Univ Hosp, Diabet Res Unit, Cardiff, Wales
Univ London Royal Holloway & Bedford New Coll, Surrey, England


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Label: Rosenstock-2008
Title: A randomised, 52-week, treat-to-target trial comparing insulin detemir with insulin glargine when administered as add-on to glucose-lowering drugs in insulin-naive people with type 2 diabetes
Journal: DIABETOLOGIA, 51 (3): 408-416 MAR 2008
Citations: 11
Authors: Rosenstock, J;Davies, M;Home, PD;Larsen, J;Koenen, C;Schernthaner, G
Addresses:
Dallas Diabet & Endocrine Ctr Med City, 7777 Forest Lane C-685, Dallas, TX 75230 USA
Dallas Diabet & Endocrine Ctr Med City, Dallas, TX 75230 USA
Univ Leicester, Cardiovasc Sci Dept, Leicester, Leics, England
Univ Newcastle, Sch Med Sci, Newcastle Upon Tyne, Tyne & Wear, England
Novo Nordisk AS, DK-2880 Bagsvaerd, Denmark
Rudolfstiftung Hosp Vienna, Dept Med, Vienna, Austria


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Label: Janka-2007
Title: Combination of oral antidiabetic agents with basal insulin versus premixed insulin alone in randomized elderly patients with type 2 diabetes mellitus
Journal: J AMER GERIAT SOC, 55 (2): 182-188 FEB 2007
Citations: 8
Authors: Janka, HU;Plewe, G;Busch, K
Addresses:
Klinikum Bremen Nord, Med Abt 2, Hammersbecker Str 228, D-28755 Bremen, Germany
Klinikum Bremen Nord, Med Abt 2, D-28755 Bremen, Germany
Diabetol Schwerpunktpraxis, Dortmund, Germany


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KEYWORDS: ALBUMIN-BOUND BASAL INSULIN ANALOGUES (INSULIN DETEMIR; TREAT-TO-TARGET TRIAL COMPARING INSULIN DETEMIR; TYPE 2 DIABETES MELLITUS; ONCE-DAILY BASAL INSULIN GLARGINE; METAANALYSIS COMPARING INSULIN GLARGINE.
[6334: (2002-2008_6) (CLI-SOC: ST Diabetes)]



Special Topics : Diabetes : INSULIN TREATMENT OF TYPE 2 DIABETES - Diabetes