The baseline time span for this database is 1998-December 31, 2008 (sixth
bimonthly period 2008). The resulting database contained 11,184 (10 years)
and 4,246 (2 years) papers. To construct the top 20 papers lists for the
past decade and the past two years, the papers were further narrowed down
by the title keywords "epigenet*." This adjustment resulted in the top 20
papers being selected from a pool of 2,510 (10 years) and 1,022 (2 years)
papers.
***Article 1 Special
Topics Interview with Rudolf Jaenisch
Total Cites: 138
Article Title: Directly reprogrammed fibroblasts show global epigenetic
remodeling and widespread tissue contribution
Authors: Maherali, N, Sridharan, R, Xie, W, Utikal, J, Eminli, S, Arnold,
K, Stadtfeld, M, Yachechko, R, Tchieu, J,
Jaenisch,
R, Plath, K, Hochedlinger, K
Journal: Cell Stem Cell
Volume: 1
Page: 55-70
Year: 2007
Addresses:
· UNIV CALIF LOS ANGELES, Johnson Comprehensive Canc Ctr, Inst Stem
Cell Biol & Med, Sch Med, Los Angeles, CA, USA
· MASSACHUSETTS GEN HOSP, Ctr Canc, Ctr Regenerat Med, Harvard Stem
Cell Inst, Boston, MA, USA
· HARVARD UNIV, Dept Mol & Cellular Biol, Cambridge, MA,
USA
· MIT, Whitehead Inst, Dept Biol, Cambridge, MA, USA
· Univ Calif Los Angeles, Johnson Comprehensive Canc Ctr, Inst Stem
Cell Biol & Med, Sch Med, Los Angeles, CA, USA
***Article 2
Total Cites: 90
Article Title: Epigenetic stem cell signature in cancer
Authors: Widschwendter, M, Fiegl, H, Egle, D, Mueller-holzner, E, Spizzo,
G, Marth, C, Weisenberger, DJ, Campan, M, Young, J, Jacobs, I, Laird,
PW
Journal: NATURE GENETICS
Volume: 39
Page: 157-158
Year: 2007
Addresses:
· UNIV SO CALIF, Norris Comprehens Canc Ctr, Dept Surg, Los Angeles,
CA, USA
· UNIV SO CALIF, Norris Comprehens Canc Ctr, Dept Biochem, Los
Angeles, CA, USA
· UNIV SO CALIF, Norris Comprehens Canc Ctr, Dept Biol Mol, Los
Angeles, CA, USA
· UCL, Inst Womens Hlth, Dept Gynecol Oncol, London, England
· Innsbruck Med Univ, Dept Obstet & Gynecol, Innsbruck,
Austria
· Innsbruck Med Univ, Dept Internal Med, Innsbruck, Austria
· QUEENSLAND INST MED RES, Mol Canc Epidemiol Lab, Brisbane,
Australia
· Univ So Calif, Norris Comprehens Canc Ctr, Dept Surg, Los Angeles,
CA, USA
***Article 3
Total Cites: 85
Article Title: Methylation of lysine 4 on histone H3: Intricacy of writing
and reading a single epigenetic mark
Authors: Ruthenburg, AJ, Allis, CD, Wysocka, J
Journal: MOLECULAR CELL
Volume: 25
Page: 15-30
Year: 2007
Addresses:
· STANFORD UNIV, Sch Med, Dept Chem & Syst Biol, Stanford, CA,
USA
· STANFORD UNIV, Sch Med, Dept Dev Biol, Stanford, CA, USA
· ROCKEFELLER UNIV, Lab Chromatin Biol, New York, NY, USA
· Stanford Univ, Sch Med, Dept Chem & Syst Biol, Stanford, CA,
USA
***Article 4
Total Cites: 74
Article Title: Stability and flexibility of epigenetic gene regulation in
mammalian development
Authors: Reik, W
Journal: NATURE
Volume: 447
Page: 425-432
Year: 2007
Addresses:
· BABRAHAM INST, Lab Dev Genet & Imprinting, Cambridge,
England
· Babraham Inst, Lab Dev Genet & Imprinting, Cambridge,
England
***Article 5
Total Cites: 57
Article Title: Epigenetic regulation in psychiatric disorders
Authors: Tsankova, N, Renthal, W, Kumar, A, Nestler, EJ
Journal: NATURE REVIEWS NEUROSCIENCE
Volume: 8
Page: 355-367
Year: 2007
Addresses:
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dept Psychiat, Dallas, TX,
USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Ctr Basic Neurosci, Dallas,
TX, USA
· Univ Texas, SW Med Ctr, Dept Psychiat, 5323 Harry Hines Blvd,
Dallas, TX, USA
***Article 6
Total Cites: 56
Article Title: Genetic and epigenetic regulators of pluripotency
Authors: Surani, MA, Hayashi, K, Hajkova, P
Journal: CELL
Volume: 128
Page: 747-762
Year: 2007
Addresses:
· UNIV CAMBRIDGE, Wellcome Trust Canc Res UK, Gurdon Inst,
Cambridge, England
· Univ Cambridge, Wellcome Trust Canc Res UK, Gurdon Inst, Tennis
Court Rd, Cambridge, England
***Article 7
Total Cites: 55
Article Title: Phenotypic plasticity and the epigenetics of human
disease
Authors: Feinberg, AP
Journal: NATURE
Volume: 447
Page: 433-440
Year: 2007
Addresses:
· JOHNS HOPKINS UNIV, Sch Med, Dept Med, Inst Basic Biomed Sci,
Baltimore, MD, USA
· JOHNS HOPKINS UNIV, Sch Med, Ctr Epigenet, Inst Basic Biomed Sci,
Baltimore, MD, USA
· Johns Hopkins Univ, Sch Med, Dept Med, Inst Basic Biomed Sci,
Baltimore, MD, USA
***Article 8
Total Cites: 55
Article Title: Transposable elements and the epigenetic regulation of the
genome
Authors: Slotkin, RK, Martienssen, R
Journal: NATURE REVIEWS GENETICS
Volume: 8
Page: 272-285
Year: 2007
Addresses:
· COLD SPRING HARBOR LAB, Cold Spring Harbor, NY, USA
· Cold Spring Harbor Lab, 1 Bungtown Rd, Cold Spring Harbor, NY,
USA
***Article 9
Total Cites: 52
Article Title: Polycomb/Trithorax response elements and epigenetic memory
of cell identity
Authors: Ringrose, L, Paro, R
Journal: DEVELOPMENT
Volume: 134
Page: 223-232
Year: 2007
Addresses:
· IMBA Inst Mol Biotechnol GmbH, Vienna, Austria
· UNIV HEIDELBERG, Zentrum Mol Biol, Heidelberg, Germany
· IMBA Inst Mol Biotechnol GmbH, Dr Bohr Gasse 3, Vienna,
Austria
***Article 11
Total Cites: 51
Article Title: Genetic unmasking of an epigenetically silenced microRNA in
human cancer cells
Authors: Lujambio, A, Ropero, S, Ballestar, E, Fraga, MF, Cerrato, C,
Setien, F, Casado, S, Suarez-gauthier, A, Sanchez-cespedes, M, Gitt, A,
Spiteri, I, Das, PP, Caldas, C, Miska, E, Esteller, M
Journal: CANCER RESEARCH
Volume: 67
Page: 1424-1429
Year: 2007
Addresses:
· CNIO, Canc Epigenet Lab, Spanish Canc Ctr, Madrid, Spain
· CNIO, Lung Canc Lab, Spanish Canc Ctr, Madrid, Spain
· UNIV POMPEU FABRA, Ctr Regulacio Genom, Barcelona, Spain
· UNIV CAMBRIDGE, Dept Biochem, Cambridge, England
· UNIV CAMBRIDGE, Wellcome Trust Canc Res UK Gurdon Inst, Cambridge,
England
· UNIV CAMBRIDGE, MRC, Canc Genom Program, Dept Oncol,Hutchison Res
Ctr, Cambridge, England
· CNIO, Canc Epigenet Lab, Spanish Canc Ctr, Melchor Fernandez
Almagro 3, Madrid, Spain
***Article 12
Total Cites: 49
Article Title: The human let-7a-3 locus contains an epigenetically
regulated microRNA gene with oncogenic function
Authors: Brueckner, B, Stresemann, C, Kuner, R, Mund, C, Musch, T, Meister,
M, Sultmann, H, Lyko, F
Journal: CANCER RESEARCH
Volume: 67
Page: 1419-1423
Year: 2007
Addresses:
· GERMAN CANC RES CTR, Div Epigenet, Heidelberg, Germany
· GERMAN CANC RES CTR, Div Mol Genome Anal, Heidelberg,
Germany
· UNIV KLINIKUM HEIDELBERG, Sekt Translat Forsch, Thoraxklin,
Heidelberg, Germany
· Deutsch Krebsforschungszentrum, Div Epigenet, Neuenheimer Feld
580, Heidelberg, Germany
***Article 13
Total Cites: 47
Article Title: Epigenetic inheritance in plants
Authors: Henderson, IR, Jacobsen, SE
Journal: NATURE
Volume: 447
Page: 418-424
Year: 2007
Addresses:
· UNIV CALIF LOS ANGELES, Howard Hughes Med Inst, Dept Mol Cell
& Dev Biol, Los Angeles, CA, USA
· Univ Calif Los Angeles, Howard Hughes Med Inst, Dept Mol Cell
& Dev Biol, Los Angeles, CA, USA
***Article 14
Total Cites: 42
Article Title: Gadd45a promotes epigenetic gene activation by
repair-mediated DNA demethylation
Authors: Barreto, G, Schafer, A, Marhold, J, Stach, D, Swaminathan, SK,
Handa, V, Doderlein, G, Maltry, N, Wu, W, Lyko, F, Niehrs, C
Journal: NATURE
Volume: 445
Page: 671-675
Year: 2007
Addresses:
· GERMAN CANC RES CTR, Div Mol Embryol, Heidelberg, Germany
· German Canc Res Ctr, Div Mol Embryol, Neuenheimer Feld 280,
Heidelberg, Germany
***Article 15
Total Cites: 38
Article Title: Epigenetic signatures of stem-cell identity
Authors: Spivakov, M, Fisher, AG
Journal: NATURE REVIEWS GENETICS
Volume: 8
Page: 263-271
Year: 2007
Addresses:
· MRC, Lymphocyte Dev Grp, Imperial Coll Sch Med, Clin Sci Ctr,
London, England
***Article 16
Total Cites: 37
Article Title: Epigenetic control of the foxp3 locus in regulatory T
cells
Authors: Floess, S, Freyer, J, Siewert, C, Baron, U, Olek, S, Polansky, J,
Schlawe, K, Chang, HD, Bopp, T, Schmitt, E, Klein-hessling, S, Serfling, E,
Hamann, A, Huehn, J
Journal: PLOS BIOLOGY
Volume: 5
Page: 169-178
Year: 2007
Addresses:
· Univ Med Berlin, Charite, Berlin, Germany
· Epiontis, Berlin, Germany
· Deutsches Rheuma Forschungszentrum, Berlin, Germany
· UNIV MAINZ, Inst Immunol, Mainz, Germany
· PATHOL INST, Abt Mol Pathol, Wurzburg, Germany
***Article 17
Total Cites: 35
Article Title: Telomere length regulates the epigenetic status of mammalian
telomeres and subtelomeres
Authors: Benetti, R, Garcia-cao, M, Blasco, MA
Journal: NATURE GENETICS
Volume: 39
Page: 243-250
Year: 2007
Addresses:
· Spanish Natl Canc Ctr, Mol Oncol Program, Telomeres &
Telomerase Grp, Madrid, Spain
***Article 18
Total Cites: 35
Article Title: Defining an epigenetic code
Authors: Turner, BM
Journal: NATURE CELL BIOLOGY
Volume: 9
Page: 39850
Year: 2007
Addresses:
· UNIV BIRMINGHAM, Sch Med, Biomed Res Inst, Birmingham,
England
· Univ Birmingham, Sch Med, Biomed Res Inst, Birmingham,
England
***Article 19
Total Cites: 32
Article Title: Molecular origins of cancer: Epigenetics in cancer
Authors: Esteller, M
Journal: NEW ENGL J MED
Volume: 358
Page: 1148-1159
Year: 2008
Addresses:
· Spanish Natl Canc Res Ctr, Canc Epigenet Lab, Madrid, Spain
· Spanish Natl Canc Res Ctr, Canc Epigenet Lab, Melchor Fernandez
Almagro 3, Madrid, Spain
***Article 20
Total Cites: 29
Article Title: Epigenetic memory at malaria virulence genes
Authors: Chookajorn, T, Dzikowski, R, Frank, M, Li, F, Jiwani, AZ, Hartl,
DL, Deitsch, KW
Journal: P NATL ACAD SCI USA
Volume: 104
Page: 899-902
Year: 2007
Addresses:
· HARVARD UNIV, Dept Organism & Evolutionary Biol, Cambridge,
MA, USA
· MAHIDOL UNIV, Fac Sci, Dept Biochem, Bangkok, Thailand
· CORNELL UNIV, Weill Med Coll, Dept Microbiol & Immunol, New
York, NY, USA
· CORNELL UNIV, Weill Med Coll, Div Int Med & Infect Dis, New
York, NY, USA
· UNIV TUBINGEN, Inst Trop Med, Tubingen, Germany
· Harvard Univ, Dept Organism & Evolutionary Biol, Cambridge,
MA, USA