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SPECIAL TOPICS

H1N1 Flu

Published: September 2009
 

The baseline time span for this database is (publication years) 1999-June 30, 2009 from the third bimonthly update (a 10-year + 6-month period). The resulting database contained 8,611 (10 years) and 13,521 (2 years) papers; 23,325 authors; 110 nations; 1,287 journals; and 5,613 institutions. See additional information below in the overview & methodology sections.

Top 20 Papers

  10-year period
  2-year period

Top 20 Overall

  Authors
  Institutions
  Journals
  Nations

Time Series

  1- & 5-year periods

Field Distribution

Interviews

  Interviews, first-person essays, and profiles about people in a wide variety of fields which pertain to this special topic of H1N1 Flu.
   

OVERVIEW

Earlier this year, a novel strain of H1N1 influenza, originally found in swine, was discovered in humans. Since this discovery, more than 70 countries throughout the world have reported cases of this strain of the flu, causing the World Health Organization to declare a pandemic. Since this declaration, cases of novel H1N1 influenza have only increased, making headlines worldwide. Though causing mild symptoms for the most part, this strain of H1N1 is still a concern due to its growing incidence, as well as the fact that other strains of H1N1 were the cause of much more serious pandemics, such as the 1918 flu pandemic.

This colorized negative stained transmission electron micrograph (TEM) depicted some of the ultrastructural morphology of the A/CA/4/09 swine flu virus.

H1N1 Influenza

This month, ScienceWatch.com looks at the literature on H1N1 influenza over the past decade and over the past two years. The database was constructed with a combination of title ("influenza A," "swine" AND "influenza") and topic ("H1N1," "swine" AND "flu") keywords. To further refine the focus for the top 20 papers over the past decade and the past two years, the title keyword "H1N1" was used.

The prevalent research themes in the past decade include detection assays, genetic and antigenic characteristics of the H1N1 strains, drug resistance, immunological issues, such as cross-protection, and vaccine trials, particularly the CAIV-T vaccination.

The themes of drug resistance and detection assays are carried over into the two-year list. In addition, genetic analyses of animal and clinical isolates are also prominent on the list. Other issues covered include virulence determinants, pathogenesis, the VLP vaccine, and a human case report involving triple reassortment infection.

Methodology: The baseline time span for this database is (publication years) 1999-June 30, 2009 from the third bimonthly update (a 10-year + 6-month period). The resulting database contained 8,611 (10 years) and 13,521 (2 years) papers; 23,325 authors; 110 nations; 1,287 journals; and 5,613 institutions. See additional information below in the overview & methodology sections.

Rankings: Once the database was in place, it was used to generate list of authors, journals, institutions, and nations. Rankings for author, journal, institution, and country are listed in three ways: according to total cites, total papers, and total cites/paper*. The paper thresholds and corresponding percentages used to determine scientist, institution, country, and journal rankings according to total cites/paper, and total papers respectively are as follows:

Entity Authors Institutions Nations Journals
Thresholds 16 45 7 5
Percentage: 1% 1% 50% 50%
*Unless otherwise specified, all rankings have a 5 paper threshold for all measures.

         



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