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SPECIAL TOPICS

Osteoporosis

Published: December 2009

The baseline time span for this database is (publication years) 1999-August 31, 2009 from the fourth bimonthly update (a 10-year + 8-month period). The resulting database contained 22,696 (10 years) and 7,124 (2 years) papers; 56,958 authors; 110 nations; 2,445 journals; and 12,241institutions. See additional information below in the overview & methodology sections.

Top 20 Papers

  10-year period
  2-year period

Top 20 Overall

  Authors
  Institutions
  Journals
  Nations

Research Front Map

  Map title: OSTEOPOROSIS

Time Series

  1- & 5-year periods

Field Distribution

Interviews

  Interviews, first-person essays, and profiles about people in a wide variety of fields which pertain to this special topic of Osteoporosis.
   

OVERVIEW

Osteoporosis is a skeletal disease characterized by loss of bone mineral density. According to the National Institute of Arthritis and Musculoskeletal and Skin Diseases, osteoporosis is a threat to approximately 44 million Americans—10 million with the disease already and 34 million with a higher risk for developing it due to low bone mass. 68% of these 44 million are women. The International Osteoporosis Foundation estimates that there are 75 million people in Europe, the United States, and Japan with osteoporosis.

Surgeon General’s Report on Bone Health & Osteoporosis, from U.S. Department of Health and Human Services.
 

In November 2002, we analyzed the literature for osteoporosis from 1992-2002. This month, ScienceWatch.com analyzes the literature on osteoporosis over the past decade and over the past two years. The initial data pool was created using the search term "osteoporosis" in titles, abstracts, and keywords of original articles, reviews, and proceedings papers published between January 1, 1999 and August 31, 2009. To make the paper lists more targeted to research specifically dealing with osteoporosis, we restricted the search further with the same keywords, but only in the titles.

Large clinical trials for the risk assessment and/or treatment of osteoporosis dominate the top papers over the past decade, including the Framingham Osteoporosis Study, EPOS, and the US PSTF studies, which examined risk assessment, and the MORE and TROPOS trials, which evaluated treatments. Other issues under scrutiny include the prevalence of vitamin D inadequacy in postmenopausal women receiving osteoporosis treatment, the incidence of osteoporosis in men undergoing androgen deprivation therapy for prostate cancer, the effects of treatment compliance on fractures, and the predictive value of bone mineral density testing.

In the past two years, papers receiving citation attention cover such topics as using parathyroid hormone to treat osteoporosis, cost-effectiveness studies, genome-wide association studies, fracture risk assessment guidelines, therapy compliance, and the specific problems associated with osteoporosis in patients who also have chronic obstructive pulmonary disease.

Methodology: The baseline time span for this database is (publication years) 1999-August 31, 2009 from the fourth bimonthly update (a 10-year + 8-month period). The resulting database contained 22,696 (10 years) and 7,124 (2 years) papers; 56,958 authors; 110 nations; 2,445 journals; and 12,241institutions. See additional information below in the overview & methodology sections.

Rankings: Once the database was in place, it was used to generate list of authors, journals, institutions, and nations. Rankings for author, journal, institution, and country are listed in three ways: according to total cites, total papers, and total cites/paper*. The paper thresholds and corresponding percentages used to determine scientist, institution, country, and journal rankings according to total cites/paper, and total papers respectively are as follows:

Entity Authors Institutions Nations Journals
Thresholds 16 74 17 5
Percentage: 1% 1% 50% 50%
*Unless otherwise specified, all rankings have a 5 paper threshold for all measures.

Photo credit:
The image above was obtained from the public document: "
Surgeon General’s Report on Bone Health & Osteoporosis."

      



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