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SPECIAL TOPICS

Tuberculosis

Published: January 2009
 

The baseline time span for this database is (publication years) 1998-August 31, 2008 from the fourth bimonthly update (a 10-year + 8-month period). The resulting database contained 13,564 (10 years) and 4,554 (2 years) papers; 37,080 authors; 163 nations; 1,570 journals; and 9,186 institutions.

Top 20 Papers

  10-year period
  2-year period

Top 20 Overall

  Authors
  Institutions
  Journals
  Nations

Research Front Map

  Map title: "TUBERCULOSIS: DIAGNOSIS AND TESTS"
  Map title: "VACCINES FOR TUBERCULOSIS, MALARIA & HIV"

Time Series

  1- & 5-year periods

Field Distribution

Interviews

  Interviews, first-person essays, and profiles about people in a wide variety of fields which pertain to this special topic of Tuberculosis.
   

OVERVIEW

Tuberculosis (TB) is a contagious infectious disease caused by Mycobacterium tuberculosis. Though it is preventable and treatable, there is a growing concern with regard to drug resistance, as well as coinfection with HIV. According to the US Centers for Disease Control, although there has been a steady decline in the incidence of TB since 1992, an excess of 14,000 cases were reported in the US in 2005. The World Health Organization estimated that there were 1.5 million deaths resulting from TB in 2006, and a further 200,000 deaths resulting from HIV-associated TB. WHO also estimates that a person with active untreated TB can infect 10-15 other people a year.

This month, ScienceWatch.com examines the literature on TB over the past decade and over the past two years, based on original articles and review papers published between 1998 and 2008 with the word "tuberculosis" in the title.

Among the topics covered in original papers published over the past decade are: whole genome studies, cell studies, susceptibility genes, gene and protein expression profiling, methods for infection typing, evolutionary speculation, and model experiments, as well as the global burden of TB and the incidence of reinfection. Another highly cited original article discusses the incidence of TB in patients being treated with infliximab. Review articles address such concerns as the burden, diagnostic standards, management, and immunology of TB.

Drug resistance and new diagnostic tests dominate the two-year listing, with nine papers. Another prevalent theme is exploring the mechanisms of TB and potential TB vaccines. Genetic diversity and host-pathogen compatibility are also covered. Review articles on this list include surveys of the incidence of TB in sub-Saharan Africa, vaccination strategies, and pro-poor healthcare policy and strategy in the developing world.

Methodology: The baseline time span for this database is (publication years) 1998-August 31, 2008 from the fourth bimonthly update (a 10-year + 8-month period). The resulting database contained 13,564 (10 years) and 4,554 (2 years) papers; 37,080 authors; 163 nations; 1,570 journals; and 9,186 institutions.

Rankings: Once the database was in place, it was used to generate list of authors, journals, institutions, and nations. Rankings for author, journal, institution, and country are listed in three ways: according to total cites, total papers, and total cites/paper. The paper thresholds and corresponding percentages used to determine scientist, institution, country, and journal rankings according to total cites/paper, and total papers respectively are as follows:

Entity Authors Institutions Nations Journals
Thresholds 16 48 16 14
Percentage: 1% 1% 50% 20%

        



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