Research front maps are diagrammatic representations of the core papers
comprising each front. They are selected from the current Research Front set
that are relevant to the featured special topic. The title for this Research
Front Map is "VACCINES FOR TUBERCULOSIS, MALARIA & HIV," containing 33 core papers. Source dates: 1998-August 31, 2008 (fifth bimonthly
period 2008).
Each circle represents a highly cited paper whose bibliographic information
is displayed when the user clicks on the circle. The solid lines between circles
represent the strongest co-citation links for each paper (that is, indicating
that the papers are frequently cited together); weaker links are indicated by
dashed lines. Papers close to each other on the map are generally more highly
co-cited. The most recent paper(s) are indicated in pink. Annotations may have
been added to this map which represent the main research themes. These appear as
labels attached to specific regions on the maps.
Note: For best results use the
"landscape orientation" option when printing this page.
Core Papers
Label: Sassetti-2003 Title: Genes required for mycobacterial growth defined by high density mutagenesis Journal: MOL MICROBIOL, 48 (1): 77-84 APR 2003 Citations: 336 Authors: Sassetti, CM;Boyd, DH;Rubin, EJ Addresses:
Harvard Univ, Sch Publ Hlth, Dept Immunol & Infect Dis, 665 Huntington Ave, Boston, MA 02115 USA
Harvard Univ, Sch Publ Hlth, Dept Immunol & Infect Dis, Boston, MA 02115 USA
Harvard Univ, Sch Med, Dept Microbiol & Mol Genet, Boston, MA 02115 USA
Label: Schnappinger-2003 Title: Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: Insights into the phagosomal environment Journal: J EXP MED, 198 (5): 693-704 SEP 1 2003 Citations: 228 Authors: Schnappinger, D;Ehrt, S;Voskuil, MI;Liu, Y;Mangan, JA;Monahan, IM;Dolganov, G;Efron, B;Butcher, PD;Nathan, C;Schoolnik, GK Addresses:
Cornell Univ, Dept Microbiol & Immunol, Weill Med Coll, 1300 York Ave, New York, NY 10021 USA
Cornell Univ, Dept Microbiol & Immunol, Weill Med Coll, New York, NY 10021 USA
Cornell Univ, Grad Program Mol Biol, Weill Grad Sch Med Sci, New York, NY 10021 USA
Cornell Univ, Grad Program Immunol, Weill Grad Sch Med Sci, New York, NY 10021 USA
Stanford Univ, Sch Med, Dept Med, Div Infect Dis & Geog Med, Stanford, CA 94305 USA
Stanford Univ, Dept Hlth Res & Policy, Stanford, CA 94305 USA
St George Hosp, Sch Med, Dept Med Microbiol, London SW17 0RE, England
Univ Calif San Francisco, Dept Med, Div Pulm & Crit Care Med, San Francisco, CA 94143 USA
Label: Pym-2002 Title: Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti Journal: MOL MICROBIOL, 46 (3): 709-717 NOV 2002 Citations: 127 Authors: Pym, AS;Brodin, P;Brosch, R;Huerre, M;Cole, ST Addresses:
Inst Pasteur, Unite Genet Mol Bacterienne, 28 Rue Dr Roux, F-75724 Paris 15, France
Inst Pasteur, Unite Genet Mol Bacterienne, F-75724 Paris 15, France
Univ Liverpool, Liverpool Sch Trop Med, Liverpool L3 5QA, Merseyside, England
Inst Pasteur, Unite Rech Expertise Histotechnol & Pathol, F-75724 Paris 15, France
Label: Mwau-2004 Title: A human immunodeficiency virus 1 (HIV-1) clade A vaccine in clinical trials: stimulation of HIV-specific T-cell responses by DNA and recombinant modified vaccinia virus Ankara (MVA) vaccines in humans Journal: J GEN VIROL, 85: 911-919 Part 4 APR 2004 Citations: 97 Authors: Mwau, M;Cebere, I;Sutton, J;Chikoti, P;Winstone, N;Wee, EGT;Beattie, T;Chen, YH;Dorrell, L;McShane, H;Schmidt, C;Brooks, M;Patel, S;Roberts, J;Conlon, C;Rowland-Jones, SL;Bwayo, JJ;McMichael, AJ;Hanke, T Addresses:
John Radcliffe Hosp, Weatherall Inst Mol Med, MRC, Human Immunol Unit, Oxford OX3 9DS, England
John Radcliffe Hosp, Weatherall Inst Mol Med, MRC, Human Immunol Unit, Oxford OX3 9DS, England
Univ St Andrews, Sch Biol, St Andrews, Fife, Scotland
John Radcliffe Hosp, Nuffield Dept Med, Oxford OX3 9DU, England
Int AIDS Vaccine Initiat, New York, NY 10038 USA
Univ Nairobi, Dept Med Microbiol, Nairobi, Kenya
Label: Munoz-Elias-2005 Title: Mycobacterium tuberculosis isocitrate lyases 1 and 2 are jointly required for in vivo growth and virulence Journal: NATURE MED, 11 (6): 638-644 JUN 2005 Citations: 82 Authors: Munoz-Elias, EJ;McKinney, JD Addresses:
Rockefeller Univ, Lab Infect Biol, 1230 York Ave, New York, NY 10021 USA
Rockefeller Univ, Lab Infect Biol, New York, NY 10021 USA
Label: Takayama-2005 Title: Pathway to synthesis and processing of mycolic acids in Mycobacterium tuberculosis Journal: CLIN MICROBIOL REV, 18 (1): 81-+ JAN 2005 Citations: 70 Authors: Takayama, K;Wang, C;Besra, GS Addresses:
Univ Wisconsin, William S Middleton Mem Vet Hosp, Sch Med, Mycobacteriol Res Lab, 2500 Overlook Terrace, Madison, WI 53705 USA
Univ Wisconsin, William S Middleton Mem Vet Hosp, Sch Med, Mycobacteriol Res Lab, Madison, WI 53705 USA
Univ Wisconsin, William S Middleton Mem Vet Hosp, Dept Med Microbiol & Immunol, Madison, WI 53705 USA
Univ Wisconsin, Dept Bacteriol, Madison, WI 53706 USA
Univ Birmingham, Sch Biosci, Birmingham B15 2TT, W Midlands, England
Label: Amino-2006 Title: Quantitative imaging of Plasmodium transmission from mosquito to mammal Journal: NATURE MED, 12 (2): 220-224 FEB 2006 Citations: 62 Authors: Amino, R;Thiberge, S;Martin, B;Celli, S;Shorte, S;Frischknecht, F;Menard, R Addresses:
Univ Fed Sao Paulo, Dept Bioquim, Rua Tres Maio 100, BR-04044020 Sao Paulo, Brazil
Inst Pasteur, Unite Biol & Genet Paludisme, F-75724 Paris 15, France
Inst Pasteur, Grp Dynam Reponses Immunes, F-75724 Paris, France
Inst Pasteur, Plate Forme Imagerie Dynam, F-75724 Paris 15, France
Label: Goonetilleke-2006 Title: Induction of multifunctional human immunodeficiency virus type 1 (HIV-1)-specific T cells capable of proliferation in healthy subjects by using a prime-boost regimen of DNA- and modified vaccinia virus Ankara-vectored vaccines expressing HIV-1 gag co Journal: J VIROL, 80 (10): 4717-4728 MAY 2006 Citations: 58 Authors: Goonetilleke, N;Moore, S;Dally, L;Winstone, N;Cebere, I;Mahmoud, A;Pinheiro, S;Gillespie, G;Brown, D;Loach, V;Roberts, J;Guimaraes-Walker, A;Hayes, P;Loughran, K;Smith, C;De Bont, J;Verlinde, C;Vooijs, D;Schmidt, C;Boaz, M;Gilmour, J;Fast, P;Dorrell, L;Hanke, T;McMichael, AJ Addresses:
Univ Oxford, CCVTM, Churchill Hosp, Old Rd, Oxford OX3 7LJ, England
Univ Oxford, Ctr Clin Vaccinol & Trop Med, Oxford, England
Univ Oxford, MRC, Human Immunol Unit, Weatherall Inst Mol Med, Oxford, England
Univ London Imperial Coll Sci Technol & Med, IAVI Core Lab, London, England
EMMES Corp, Rockville, MD USA
Int AIDS Vaccine Initiat, New York, NY USA
Label: Filliol-2006 Title: Global phylogeny of Mycobacterium tuberculosis based on single nucleotide polymorphism (SNP) analysis: Insights into tuberculosis evolution, phylogenetic accuracy of other DNA fingerprinting systems, and recommendations for a minimal standard SNP set Journal: J BACTERIOL, 188 (2): 759-772 JAN 2006 Citations: 51 Authors: Filliol, I;Motiwala, AS;Cavatore, M;Qi, WH;Hazbon, MH;del Valle, MB;Fyfe, J;Garcia-Garcia, L;Rastogi, N;Sola, C;Zozio, T;Guerrero, MI;Leon, CI;Crabtree, J;Angiuoli, S;Eisenach, KD;Durmaz, R;Joloba, ML;Rendon, A;Sifuentes-Osornio, J;de Leon, AP;Cave, MD;Fleischmann, R;Whittam, TS;Alland, D Addresses:
Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Med, Div Infect Dis, 185 S Orange Ave, Newark, NJ 07103 USA
Univ Med & Dent New Jersey, New Jersey Med Sch, Dept Med, Div Infect Dis, Newark, NJ 07103 USA
Univ Med & Dent New Jersey, New Jersey Med Sch, Ruy V Lourence Ctr Study Emerging & Reemerging Pa, Newark, NJ 07103 USA
Michigan State Univ, Toxicol Ctr, E Lansing, MI 48824 USA
Inst Genom Res, Rockville, MD USA
Univ Arkansas Med Sci, CAVHS, Dept Pathol, Little Rock, AR 72205 USA
Univ Arkansas Med Sci, CAVHS, Dept Immunol Microbiol, Little Rock, AR 72205 USA
Univ Arkansas Med Sci, CAVHS, Dept Neurobiol, Little Rock, AR 72205 USA
Univ Arkansas Med Sci, CAVHS, Dept Dev Sci, Little Rock, AR 72205 USA
Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Dept Infect Dis, Mexico City, DF, Mexico
Inst Nacl Salud Publ, Unidad TB, Mexico City, DF, Mexico
Univ Autonoma Nuevo Leon, Univ Hosp Monterrey, Pulm Serv, Nuevo Leon, Mexico
Victorian Infect Dis Reference Lab, Victorian Mycobacterium Reference Lab, Melbourne, Vic 3051, Australia
Inst Pasteur Guadeloupe, Unite TB & Mycobacteries, Abymes 97183, Guadeloupe
Inst Nacl Salud, Grp Micobacterias, Subdirecc Invest, Bogota, Colombia
Inonu Univ, Fac Med, Dept Clin Microbiol, Malatya, Turkey
Makerere Univ, Dept Med, Kampala, Uganda
Makerere Univ, Dept Med Microbiol, Kampala, Uganda
Label: Gagneux-2006 Title: Variable host-pathogen compatibility in Mycobacterium tuberculosis Journal: PROC NAT ACAD SCI USA, 103 (8): 2869-2873 FEB 21 2006 Citations: 48 Authors: Gagneux, S;DeRiemer, K;Van, T;Kato-Maeda, M;de Jong, BC;Narayanan, S;Nicol, M;Niemann, S;Kremer, K;Gutierrez, MC;Hilty, M;Hopewell, PC;Small, PM Addresses:
Inst Syst Biol, 1441 N 34th St, Seattle, WA 98103 USA
Inst Syst Biol, Seattle, WA 98103 USA
Stanford Univ, Med Ctr, Div Infect Dis & Geog Med, Stanford, CA 94305 USA
Univ Calif Davis, Sch Med, Davis, CA 95616 USA
San Francisco Gen Hosp, Div Pulm & Crit Care Med, San Francisco, CA 94110 USA
Univ Calif San Francisco, San Francisco, CA 94110 USA
MRC Labs, Fajara, Gambia
Tuberculosis Res Ctr, Dept Immunol, Madras 600031, Tamil Nadu, India
Univ Cape Town, Inst Infect Dis & Mol Med, ZA-7925 Cape Town, South Africa
Natl Reference Ctr Mycobacteria, Forschungszentrum, D-23848 Borstel, Germany
Natl Inst Publ Hlth & Environm, Mycobacteria Reference Unit, NL-3720 BA Bilthoven, Netherlands
Swiss Trop Inst, CH-4002 Basel, Switzerland
Inst Pasteur, Mycobacteria Reference Lab, F-75724 Paris, France
Bill & Melinda Gates Fdn, Seattle, WA 98102 USA
Label: Trunz-2006 Title: Effect of BCG vaccination on childhood tuberculous meningitis and miliarytuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness Journal: LANCET, 367 (9517): 1173-1180 APR 8 2006 Citations: 46 Authors: Trunz, BB;Fine, PEM;Dye, C Addresses:
WHO, HIV AIDS TB & Malaria, CH-1211 Geneva 27, Switzerland
WHO, HIV AIDS TB & Malaria, CH-1211 Geneva 27, Switzerland
London Sch Hyg & Trop Med, Infect Dis Epidemiol Unit, London WC1, England
Label: Hanke-2007 Title: Clinical experience with plasmid DNA- and modified vaccinia virus Ankara-vectored human immunodeficiency virus type 1 clade A vaccine focusing on T-cell induction Journal: J GEN VIROL, 88: 1-12 Part 1 JAN 2007 Citations: 25 Authors: Hanke, T;McMichael, AJ;Dorrell, L Addresses:
Univ Oxford, MRC, Human Immunol Unit, Weatherall Inst Mol Med, Oxford OX3 9DS, England
Univ Oxford, MRC, Human Immunol Unit, Weatherall Inst Mol Med, Oxford OX3 9DS, England
Label: Bejon-2006 Title: A phase 2b randomised trial of the candidate malaria vaccines FP9 ME-TRAP and MVA ME-TRAP among children in Kenya Journal: PLOS CLIN TRIALS, 1 (6): art. no.-e29 OCT 20 2006 Citations: 21 Authors: Bejon, P;Mwacharo, J;Kai, O;Mwangi, T;Milligan, P;Todryk, S;Keating, S;Lang, T;Lowe, B;Gikonyo, C;Molyneux, C;Fegan, G;Gilbert, SC;Peshu, N;Marsh, K;Hill, AVS Addresses:
Kenya Govt Med Res Ctr, Ctr Geog Med Res Coast, Kilifi, Kenya
Kenya Govt Med Res Ctr, Ctr Geog Med Res Coast, Kilifi, Kenya
Univ Oxford, Ctr Clin Vaccinol & Trop Med, Oxford, England
London Sch Hyg & Trop Med, London WC1, England
Univ Oxford, Wellcome Trust Ctr Human Genet, Oxford, England
Univ Oxford, John Radcliffe Hosp, Nuffield Dept Clin Med, Oxford OX3 9DU, England
Label: Amino-2007 Title: Imaging malaria sporozoites in the dermis of the mammalian host Journal: NAT PROTOC, 2 (7): 1705-1712 2007 Citations: 7 Authors: Amino, R;Thiberge, S;Blazquez, S;Baldacci, P;Renaud, O;Shorte, S;Menard, R Addresses:
Univ Fed Sao Paulo, Dept Bioquim, Rua Tres de Maio 100, BR-04044020 Sao Paulo, SP, Brazil
Inst Pasteur, Unite Biol & Genet Paludisme, F-75724 Paris 15, France
Label: Gandotra-2007 Title: In vivo gene silencing identifies the Mycobacterium tuberculosis proteasome as essential for the bacteria to persist in mice Journal: NATURE MED, 13 (12): 1515-1520 DEC 2007 Citations: 4 Authors: Gandotra, S;Schnappinger, D;Monteleone, M;Hillen, W;Ehrt, S Addresses:
Weill Cornell Med Coll, Dept Microbiol & Immunol, 1300 York Ave, New York, NY 10065 USA
Weill Cornell Med Coll, Dept Microbiol & Immunol, New York, NY 10065 USA
Cornell Univ, Weill Grad Sch Med Sci, Program Immunol & Microbial Pathogenesis, New York, NY 10065 USA
Cornell Univ, Weill Grad Sch Med Sci, Program Mol Biol, New York, NY 10065 USA
Univ Erlangen Nurnberg, Lehrstuhl Mikrobiol, D-91058 Erlangen, Germany