Archive ScienceWatch

Siegfried Blechert & Stephen Connon talk with and answer a few questions about this month's Emerging Research Front Paper in the field of Chemistry.
Blechert Article: Recent developments in olefin cross-metathesis
Authors: Connon, SJ;Blechert, S
Journal: ANGEW CHEM INT ED, 42 (17): 1900-1923 2003
Addresses: Tech Univ Berlin, Inst Chem, Str 17 Juni 135, D-10623 Berlin, Germany.
Tech Univ Berlin, Inst Chem, D-10623 Berlin, Germany.

Why do you think your paper is highly cited?

Our article reviewed cross-metathesis methodologies at a time when their significant potential was beginning to be recognized. We tried to put together the most comprehensive review possible at the time.

Does it describe a new discovery, methodology, or synthesis of knowledge?

It describes ingenious developments in both methodology and catalyst design by many scientists around the world in the area of cross-metathesis.

Would you summarize the significance of your paper in layman's terms?

Our paper brought together the leading developments in the field of olefin cross-metathesis up to 2002 in a single article. While experts in the area would have been aware of these advances already, it was our hope that the article could bring the potential of this powerful reaction which allows the coupling of two (usually) readily prepared alkene fragments under mild conditions to the attention of the wider synthetic research community.

Prof. Dr. Siegfried Blechert
Technische Universität Berlin
Institut für Chemie
Berlin, Germany

Stephen J. Connon, B.Sc., Ph.D.
Lecturer in Organic Chemistry
Department of Chemistry
Trinity College Dublin
Dublin, Ireland

Related: Research Front Map on MITOCHONDRIAL REACTIVE OXYGEN SPECIES (from Biology & Biochemistry, April 2008)

Keywords: olefin cross-metathesis, alkene fragments.

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2008 : August 2008 : Siegfried Blechert & Stephen Connon