Hoong-Kun Fun talks with
ScienceWatch.com and answers a few questions about
this month's Fast Moving Front Paper in the field of Chemistry.
The author has also sent along images of his work.
Article: 4-chloro-N
'-[(Z)-4-(dimethylamino)benzylidene]benzohydrazide
monohydrate
Authors: Fun, HK;Patil, PS;Jebas, SR;Sujith,
KV;Kalluraya, B
Journal: ACTA CRYSTALLOGR E-STRUCT REP, 64: O1594-O1595 Part 8
AUG 2008
Addresses: Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit,
George Town 11800, Malaysia.
Univ Sains Malaysia, Sch Phys, Xray Crystallog Unit, George
Town 11800, Malaysia.
Mangalore Univ, Dept Studies Phys, Mangalagangothri 574199,
Karnataka, India. (addresses have been
truncated.)
Why do you think your paper is highly
cited?
This article is relatively highly cited because quite a large number of
researchers are interested in the properties of hydrazones and their
derivatives which includes antimicrobial, anticonvulsant, analgesic,
anti-inflammatory, anti-platelet, anti-tubercular, anticancer, and
anti-tumor activities. These materials are candidates for new drug
development.
Does it describe a new discovery, methodology, or
synthesis of knowledge? Would you summarize the significance of your
paper in layman's terms?
This article reported a new hydrazone structure determined by single
crystal structure determination and represents an international
collaborative research effort of scientists from the Universiti Sains
Malaysia in Penang, Malaysia, the Prince of Songkla University in Songkla,
Thailand, and Mangalore University in Karnataka, India.
Professor Hoong-Kun Fun, F.A.Sc.
X-ray Crystallography Unit
School of Physics
University of Science, Malaysia (USM)
Penang, Malaysia Web |
Web (Researcher ID Profile)
KEYWORDS: HYDRAZONES; DERIVATIVES; NEW DRUG DEVELOPMENT.
The plot and packing of this structure are given below:
Fig. 1: The molecular structure of
4-chloro-N’-[(Z)-4-nitrobenzylidene]benzohydrazide
monohydrate
Fig. 2: The packing diagram viewed along the a-axis of
4-chloro-N’-[(Z)-4-nitrobenzylidene]benzohydrazide
monohydrate. Hydrogen bonds are shown as dash lines.