Fast Moving Fronts> May 2011

Year 2011

This image shows a snapshot from a simulation that revealed for the first time how the AIDS drug target HIV protease opens to allow a small molecule inhibitor (green) to enter and inactivate it. The protein is shown in a schematic ribbon representation; the simulations were done at the atomic level.From the database of Essential Science IndicatorsSM from Clarivate Analytics, this list of Fast Moving Fronts has been generated by a comparison of the data sets for the current period of January 2005-December 31, 2010, and the previous period of November 2004-October 31, 2010 (sliding 6-year period).

As part of this bimonthly processing, Special Topics identifies the Research Fronts that are growing most rapidly in each of the 22 major fields covered by Essential Science Indicators. Fast Moving Fronts are those having the largest percentage increase in number of core papers from one period to the next in their respective fields. Some author(s) of the comments below have also sent along accompanying images/descriptions of their work.

Field Research Front Name
Agricultural Sciences VITAMIN E REGULATORY MECHANISMS; VITAMIN STILL AWAITING; ALPHA-TOCOPHEROL ACTION; BIOLOGICAL FUNCTION; MOLECULAR MECHANISM
Biology & Biochemistry Carlos Simmerling HUMAN MESENCHYMAL STEM CELLS; MESENCHYMAL STEM CELLS MODIFIED; MESENCHYMAL STEM CELLS OVEREXPRESSING AKT DRAMATICALLY REPAIR INFARCTED MYOCARDIUM; AKT-MODIFIED MESENCHYMAL STEM CELL-MEDIATED CARDIAC PROTECTION; MESENCHYMAL STEM CELL HOMING
Fast Moving Front Commentary: " Carlos Simmerling Discusses the Importance of Computer Simulations."
Chemistry POROUS METAL-ORGANIC FRAMEWORK [ZN4O(NTB)(2)]; GUEST-INDUCED DRASTIC SINGLE-CRYSTAL-TO-SINGLE-CRYSTAL TRANSFORMATIONS; METAL-ORGANIC POROUS SOLID; HIGHLY POROUS; REDOX ACTIVE PILLARED BILAYER OPEN FRAMEWORK
Clinical Medicine HUMAN MONOCYTE-DERIVED DENDRITIC CELLS; HUMAN NK CELL LINE EXPOSED; PLANT EXTRACT CONTAINING HUMAN PAPILLOMAVIRUS 16-E7 PROTEIN; MALIGNANT CELLS; INFLAMMATORY CELLS
Computer Science MOLECULAR DYNAMICS SIMULATIONS; AMBER BIOMOLECULAR SIMULATION PROGRAMS; MULTIPLE AMBER FORCE FIELDS; ALL-ATOM EQUILIBRIUM ENSEMBLE SIMULATIONS; AUTOMATIC ATOM TYPE
Economics & Business MONETARY INCENTIVES; SOCIAL IMAGE; IMAGE MOTIVATION; WAGE INEQUALITY; PERFORMANCE PAY
Engineering Gustavo Camps-Valls HYPERSPECTRAL IMAGE CLASSIFICATION; HYPERSPECTRAL DATA; SVMS; HYPERSPECTRAL IMAGE DATA; HYPERSPECTRAL IMAGES USING MINIMUM SPANNING FOREST GROWN; NEAREST NEIGHBOR CLASSIFICATION
Fast Moving Front Commentary: " Gustavo Camps-Valls on Kernel-Based Methods for Hyperspectral Image Classification."
Environment/ Ecology SOCIAL-ECOLOGICAL SYSTEM RESILIENCE; SOCIAL-ECOLOGICAL RESILIENCE; URBAN ENVIRONMENTAL EDUCATION; RESILIENCE SYSTEMS FRAMEWORK; EXPLORING LEARNING OPPORTUNITIES
Geosciences SURFACE TEMPERATURE VARIATIONS; RECENT CLIMATE VARIABILITY; CLIMATE CHANGE; RISING TEMPERATURE; SOUTHERN HEMISPHERE ANNULAR MODE
Immunology T CELLS MYELOID LINEAGE POTENTIAL; EARLY T CELL LINEAGE COMMITMENT CHECKPOINT DEPENDENT; ADULT T-CELL PROGENITORS RETAIN MYELOID POTENTIAL; ADULT BLOOD LINEAGE COMMITMENT; BLOOD IMPLICATES COMMON LYMPHOID PROGENITORS
Materials & Science CRYSTALLINE DIBLOCK CONJUGATED COPOLYMERS; CRYSTALLINE RANDOM CONJUGATED COPOLYMERS; ALL-CONJUGATED BLOCK COPOLYMERS; BLOCK COPOLYMER TEMPLATES; BULK HETEROJUNCTION SOLAR CELLS USING BLOCK COPOLY(3-ALKYLTHIOPHENE)S
Mathematics MULTIDIMENSIONAL PARTIAL DIFFERENTIAL EQUATIONS; SEPARATED REPRESENTATIONS; APPLICATIONS; NON INCREMENTAL STRATEGIES; KINETIC THEORY MODELING
Microbiology Benjamin Chen HUMAN IMMUNODEFICIENCY VIRUS TYPE 1; HUMAN IMMUNODEFICIENCY VIRUS TRANSFER; MEMBRANE NANOTUBES PHYSICALLY CONNECT T CELLS; VIROLOGICAL SYNAPSE-MEDIATED SPREAD; BIOFILM-LIKE EXTRACELLULAR VIRAL ASSEMBLIES MEDIATE HTLV-1 CELL-TO-CELL TRANSMISSION
Fast Moving Front Commentary: " Benjamin Chen on a New Viral Technology."
Molecular Biology & Genetics GENOME ANALYSIS; GENOME SEQUENCE; MARSUPIAL MONODELPHIS DOMESTICA REVEALS INNOVATION; PLATYPUS REVEALS UNIQUE SIGNATURES; COMPARATIVE ANALYSIS
Multidisciplinary MEIOTIC RECOMBINATION HOTSPOTS; MAMMALIAN RECOMBINATION HOTSPOTS; PRDM9 CONTROLS ACTIVATION; PRDM9 GENE; PRIMATES IMPLICATES
Neuroscience & Behavior A. D. (Bud) Craig WHITE MATTER DEVELOPMENT; GRAY MATTER INDUCED; TRAINING INDUCES CHANGES; REMEDIATION-INDUCED CHANGES; EXTENSIVE PIANO PRACTICING
Fast Moving Front Commentary: " A. D. (Bud) Craig on the Anterior Insula and Human Awareness."
Pharmacology & Toxicology CYCLODEXTRINS; PHARMACCUTICAL SOLUBILIZERS; 2-HYDROXYPROPYL-BETA-CYCLODEXTRIN (HP-BETA-CD); TOXICOLOGY REVIEW; COMPLEX AGGREGATES
Physics CHARGED LIFSHITZ BLACK HOLES; ANALYTIC LIFSHITZ BLACK HOLES; HIGHER DIMENSIONS
Plant & Animal Science Laura Airoldi & Michael W. Beck GLOBE THREATENS COASTAL ECOSYSTEMS; COASTAL MARINE HABITATS; COASTAL SEAS; BIODIVERSITY LOSS; ACCELERATING LOSS
Fast Moving Front Commentary: " Laura Airoldi & Michael Beck on European Coastal Marine Habitats."
Psychiatry/
Psychology
ANTERIOR INSULA; INSULA ACTIVATION; ANXIETY-PRONE SUBJECTS; EMOTION PROCESSING; HUMAN AWARENESS
Social Sciences, general HUMAN ENAMEL FORMATION TIMES; MODERN HUMAN LIFE HISTORY; MODERN HUMAN MOLARS; RAPID DENTAL DEVELOPMENT; NEANDERTAL LIFE HISTORIES
Space Science Alessandro Morbidelli DEBRIS DISKS; GIANT PLANETS; TERRESTRIAL PLANETS; ORIGIN; CATACLYSMIC LATE HEAVY BOMBARDMENT PERIOD
Fast Moving Front Commentary: " Alessandro Morbidelli on the Structure of the Solar System."
(2004-2010_6)
 
 

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Featured Image:

The image shows a snapshot from a simulation exploring how a DNA repair enzyme binds to and bends the DNA duplex in its search for damage. DNA repair occurs thousands of times a day in every cell and every organism.

An image from a Fast Moving Front (Biology & Biochemistry) commentary titled: " Carlos Simmerling Discusses the Importance of Computer Simulations."