"Genome-wide association defines more than 30 distinct
susceptibility loci for Crohn's disease," by Jeffrey C. Barrett
and 60 others, Nature Genetics, 40(8): 955-62, August 2008.
Abstract: "Several risk factors for Crohn's disease have
been identified in recent genome-wide association studies. To advance gene
discovery further, we combined data from three studies on Crohn's disease
(a total of 3,230 cases and 4,829 controls) and carried out replication in
3,664 independent cases with a mixture of population-based and family-based
controls. The results strongly confirm 11 previously reported loci and
provide genome-wide significant evidence for 21 additional loci, including
the regions containing STAT3, JAK2, ICOSLG, CDKAL1 and ITLN1. The expanded
molecular understanding of the basis of this disease offers promise for
informed therapeutic development."
This report from Nature Genetics was cited 49
times in current journal articles indexed by Clarivate
during November-December 2009. During that two-month period, only one other
biology paper published in the last two years, not counting reviews,
collected a higher number of citations. Prior to the most recent bimonthly
count, citations to the paper have accrued as follows:
SOURCE:
Hot Papers Database (Included with a subscription to the print
newsletter
Science Watch®, available from the
Research Services
Group of Thomson
Reuters. Packaged on a CD that is mailed with each Science
Watch issue, the Hot Papers Database contains data on hundreds of
highly cited papers published during the last two years. User interface
permits searching by author, organization, journal, field, and more. Total
citations, as well as citations accrued during successive bimonthly
periods, can be assessed and graphed. An updated CD containing the most
recent bimonthly data is mailed with every new issue of Science
Watch, six times a year. The CD also includes an electronic version of
the Science Watch issue in HTML format, for personal desktop
access.