As part of this bimonthly processing,
ScienceWatch.com selects the Research Fronts with the largest absolute
increase in size in each of the 22 major
fields covered by
Essential Science IndicatorsSM
from Thomson
Reuters. The size of a research front is determined by the number of
core papers it contains. This Research Front on NOVEL DRUG DELIVERY
PLATFORMS WITH DENDRIMERS from the field of Pharmacology & Toxicology was
selected for mapping from the list of Top Topics for June 2008
(data from the first bimonthly period of
2008). The map is a diagrammatic
representation of the 34 core papers comprising the front
in
Pharmacology & Toxicology.
Each circle
represents a highly cited paper whose bibliographic information is displayed
when the user clicks on the circle. The lines between circles represent the
strongest co-citation links for each paper (that is, indicating that the papers
are frequently cited together). Papers close to each other on the map are
generally more highly co-cited. The most recent paper(s) are indicated in pink.
Core Papers
Label: Stiriba-2002 Title: Dendritic polymers in biomedical applications: From potential to clinical use in diagnostics and therapy Journal: ANGEW CHEM INT ED, 41 (8): 1329-1334 2002 Citations: 227 Authors: Stiriba, SE;Frey, H;Haag, R Addresses:
Univ Freiburg, Inst Makromol Chem, Stefan Meier Str 21-31, D-79104 Freiburg, Germany
Univ Freiburg, Inst Makromol Chem, D-79104 Freiburg, Germany
Univ Freiburg, Freiburger Mat Forschungszentrum, FMF, D-79104 Freiburg, Germany
Label: Lee-2005 Title: Designing dendrimers for biological applications Journal: NAT BIOTECHNOL, 23 (12): 1517-1526 DEC 2005 Citations: 109 Authors: Lee, CC;MacKay, JA;Frechet, JMJ;Szoka, FC Addresses:
Univ Calif San Francisco, Dept Biopharmaceut Sci & Pharmaceut Chem, San Francisco, CA 94143 USA
Univ Calif San Francisco, Dept Biopharmaceut Sci & Pharmaceut Chem, San Francisco, CA 94143 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Label: Gillies-2005 Title: Dendrimers and dendritic polymers in drug delivery Journal: DRUG DISCOV TODAY, 10 (1): 35-43 JAN 1 2005 Citations: 103 Authors: Gillies, ER;Frechet, JMJ Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Label: DeJesus-2002 Title: Polyester dendritic systems for drug delivery applications: In vitro and in vivo evaluation Journal: BIOCONJUGATE CHEMISTRY, 13 (3): 453-461 MAY-JUN 2002 Citations: 94 Authors: De Jesus, OLP;Ihre, HR;Gagne, L;Frechet, JMJ;Szoka, FC Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif San Francisco, Sch Pharm, San Francisco, CA 94143 USA
Label: Kukowska-Latallo-2005 Title: Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer Journal: CANCER RES, 65 (12): 5317-5324 JUN 15 2005 Citations: 76 Authors: Kukowska-Latallo, JF;Candido, KA;Cao, ZY;Nigavekar, SS;Majoros, IJ;Thomas, TP;Balogh, LP;Khan, MK;Baker, JR Addresses:
Univ Michigan, Hlth Syst, Ctr Biol Nanotechnol, 1150 W Med Ctr Dr,9220 MSRB3, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Dept Radiat Oncol, Ann Arbor, MI 48109 USA
Label: Majoros-2006 Title: PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, and functionality Journal: BIOMACROMOLECULES, 7 (2): 572-579 FEB 2006 Citations: 48 Authors: Majoros, IJ;Myc, A;Thomas, T;Mehta, CB;Baker, JR Addresses:
Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, 200 Zina Pitcher Pl,4027 Kresge 2, Ann Arbor, MI 48109 USA
Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA
Label: Maiti-2005 Title: Effect of solvent and pH on the structure of PAMAM dendrimers Journal: MACROMOLECULES, 38 (3): 979-991 FEB 8 2005 Citations: 41 Authors: Maiti, PK;Cagin, T;Lin, ST;Goddard, WA Addresses:
CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA 91125 USA
CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA 91125 USA
Label: Patri-2005 Title: Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2203-2214 DEC 14 2005 Citations: 34 Authors: Patri, AK;Kukowska-Latallo, JF;Baker, JR Addresses:
Nanotechnol Inst Med & Biol Sci, Div Clin Immunol & Allergy, Dept Internal Med, 9220 MSRB III, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA
Label: Qiu-2006 Title: Polymer architecture and drug delivery Journal: PHARMACEUT RES, 23 (1): 1-30 JAN 2006 Citations: 24 Authors: Qiu, LY;Bae, YH Addresses:
Univ Utah, Dept Pharmaceut & Pharmaceut Chem, 421 Wakara Way,Suite 315, Salt Lake City, UT 84108 USA
Univ Utah, Dept Pharmaceut & Pharmaceut Chem, Salt Lake City, UT 84108 USA
Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310031, Peoples R China
Label: Shabat-2006 Title: Self-immolative dendrimers as novel drug delivery platforms Journal: J POLYM SCI A-POLYM CHEM, 44 (5): 1569-1578 MAR 1 2006 Citations: 22 Authors: Shabat, D Addresses:
Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Label: Tomalia-2007 Title: Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging Journal: BIOCHEM SOC TRANS, 35: 61-67 Part 1 FEB 2007 Citations: 11 Authors: Tomalia, DA;Reyna, LA;Svenson, S Addresses:
Dendrit Nanotechnol Inc, 2625 Denison Dr, Mt Pleasant, MI 48858 USA
Dendrit Nanotechnol Inc, Mt Pleasant, MI 48858 USA
Cent Michigan Univ, Dept Chem, Mt Pleasant, MI 48859 USA
Label: Antoni-2007 Title: A chemoselective approach for the accelerated synthesis of well-defined dendritic architectures Journal: CHEM COMMUN, (22): 2249-2251 JUN 14 2007 Citations: 9 Authors: Antoni, P;Nystrom, D;Hawker, CJ;Hult, A;Malkoch, M Addresses:
Royal Inst Technol, Teknikringen S6-58, SE-10044 Stockholm, Sweden
Royal Inst Technol, SE-10044 Stockholm, Sweden
Univ Calif Santa Barbara, Mat Res Lab, Santa Barbara, CA 93106 USA
Label: Chandrasekar-2007 Title: The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats Journal: BIOMATERIALS, 28 (3): 504-512 JAN 2007 Citations: 8 Authors: Chandrasekar, D;Sistla, R;Ahmad, FJ;Khar, RK;Diwan, PV Addresses:
Indian Inst Chem Technol, Div Pharmacol, Uppal Rd, Hyderabad 500007, Andhra Pradesh, India
Indian Inst Chem Technol, Div Pharmacol, Hyderabad 500007, Andhra Pradesh, India
Jamia Hamdard Deemed Univ, Fac Pharm, Dept Pharmaceut, New Delhi, India