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 ScienceWatch

As part of this bimonthly processing, ScienceWatch.com selects the Research Fronts with the largest absolute increase in size in each of the 22 major fields covered by Essential Science IndicatorsSM from Thomson Reuters. The size of a research front is determined by the number of core papers it contains. This Research Front on NOVEL DRUG DELIVERY PLATFORMS WITH DENDRIMERS from the field of Pharmacology & Toxicology was selected for mapping from the list of Top Topics for June 2008 (data from the first bimonthly period of 2008). The map is a diagrammatic representation of the 34 core papers comprising the front in Pharmacology & Toxicology.

Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together). Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in pink. Stiriba-2002 Luo-2002 Ihre-2002 DeJesus-2002 Patri-2002 Quintana-2002 Cloninger-2002 Aulenta-2003 Boas-2004 Caminade-2004 Ballauff-2004 Delort-2004 Chase-2004 Gillies-2005 Maiti-2005 Kukowska-Latallo-2005 Lee-2005 D Dufes-2005 Patri-2005 Duncan-2005 Kobayashi-2005 Yang-2006 Qiu-2006 Majoros-2006 Shabat-2006 Talanov-2006 Darbre-2006 Chandrasekar-2007 Gingras-2007 Tomalia-2007 Lo-2007 Paleos-2007 Antoni-2007

NOVEL DRUG DELIVERY PLATFORMS WITH DENDRIMERS


 Core Papers

Label: Stiriba-2002
Title: Dendritic polymers in biomedical applications: From potential to clinical use in diagnostics and therapy
Journal: ANGEW CHEM INT ED, 41 (8): 1329-1334 2002
Citations: 227
Authors: Stiriba, SE;Frey, H;Haag, R
Addresses:
Univ Freiburg, Inst Makromol Chem, Stefan Meier Str 21-31, D-79104 Freiburg, Germany
Univ Freiburg, Inst Makromol Chem, D-79104 Freiburg, Germany
Univ Freiburg, Freiburger Mat Forschungszentrum, FMF, D-79104 Freiburg, Germany


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Label: Boas-2004
Title: Dendrimers in drug research
Journal: CHEM SOC REV, 33 (1): 43-63 JAN 10 2004
Citations: 189
Authors: Boas, U;Heegaard, PMH
Addresses:
Danish Vet Inst, Dept Immunol & Biochem, Bulowsvej 27, DK-1790 Copenhagen, Denmark
Danish Vet Inst, Dept Immunol & Biochem, DK-1790 Copenhagen, Denmark


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Label: Cloninger-2002
Title: Biological applications of dendrimers
Journal: CURR OPIN CHEM BIOL, 6 (6): 742-748 DEC 2002
Citations: 165
Authors: Cloninger, MJ
Addresses:
Montana State Univ, Dept Chem & Biochem, 108 Gaines Hall, Bozeman, MT 59717 USA
Montana State Univ, Dept Chem & Biochem, Bozeman, MT 59717 USA


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Label: Patri-2002
Title: Dendritic polymer macromolecular carriers for drug delivery
Journal: CURR OPIN CHEM BIOL, 6 (4): 466-471 AUG 2002
Citations: 135
Authors: Patri, AK;Majoros, IJ;Baker, JR
Addresses:
Univ Michigan, Dept Internal Med, Ctr Biol Nanotechnol, 9220C MSRB 3,1150 W Med Ctr Dr, Ann Arbor, MI 48109 USA
Univ Michigan, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA


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Label: Quintana-2002
Title: Design and function of a dendrimer-based therapeutic nanodevice targeted to tumor cells through the folate receptor
Journal: PHARMACEUT RES, 19 (9): 1310-1316 SEP 2002
Citations: 135
Authors: Quintana, A;Raczka, E;Piehler, L;Lee, I;Myc, A;Majoros, I;Patri, AK;Thomas, T;Mule, J;Baker, JR
Addresses:
Univ Michigan, Sch Med, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
Univ Michigan, Sch Med, Dept Internal Med, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA


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Label: Lee-2005
Title: Designing dendrimers for biological applications
Journal: NAT BIOTECHNOL, 23 (12): 1517-1526 DEC 2005
Citations: 109
Authors: Lee, CC;MacKay, JA;Frechet, JMJ;Szoka, FC
Addresses:
Univ Calif San Francisco, Dept Biopharmaceut Sci & Pharmaceut Chem, San Francisco, CA 94143 USA
Univ Calif San Francisco, Dept Biopharmaceut Sci & Pharmaceut Chem, San Francisco, CA 94143 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA


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Label: Gillies-2005
Title: Dendrimers and dendritic polymers in drug delivery
Journal: DRUG DISCOV TODAY, 10 (1): 35-43 JAN 1 2005
Citations: 103
Authors: Gillies, ER;Frechet, JMJ
Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA


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Label: Luo-2002
Title: Poly(ethylene glycol)-conjugated PAMAM dendrimer for biocompatible, high-efficiency DNA delivery
Journal: MACROMOLECULES, 35 (9): 3456-3462 APR 23 2002
Citations: 103
Authors: Luo, D;Haverstick, K;Belcheva, N;Han, E;Saltzman, WM
Addresses:
Cornell Univ, Sch Chem Engn, 120 Olin Hall, Ithaca, NY 14850 USA
Cornell Univ, Sch Chem Engn, Ithaca, NY 14850 USA


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Label: Aulenta-2003
Title: Dendrimers: a new class of nanoscopic containers and delivery devices
Journal: EUR POLYM J, 39 (9): 1741-1771 SEP 2003
Citations: 99
Authors: Aulenta, F;Hayes, W;Rannard, S
Addresses:
Univ Reading, Sch Chem, Reading RG6 6AH, Berks, England
Univ Reading, Sch Chem, Reading RG6 6AH, Berks, England
Unilever Res & Dev, Wirral CH63 3JW, Merseyside, England


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Label: Ihre-2002
Title: Polyester dendritic systems for drug delivery applications: Design, synthesis, and characterization
Journal: BIOCONJUGATE CHEMISTRY, 13 (3): 443-452 MAY-JUN 2002
Citations: 97
Authors: Ihre, HR;De Jesus, OLP;Szoka, FC;Frechet, JMJ
Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif San Francisco, Sch Pharm, San Francisco, CA 94143 USA


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Label: DeJesus-2002
Title: Polyester dendritic systems for drug delivery applications: In vitro and in vivo evaluation
Journal: BIOCONJUGATE CHEMISTRY, 13 (3): 453-461 MAY-JUN 2002
Citations: 94
Authors: De Jesus, OLP;Ihre, HR;Gagne, L;Frechet, JMJ;Szoka, FC
Addresses:
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif Berkeley, Dept Chem, Berkeley, CA 94720 USA
Univ Calif San Francisco, Sch Pharm, San Francisco, CA 94143 USA


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Label: Kukowska-Latallo-2005
Title: Nanoparticle targeting of anticancer drug improves therapeutic response in animal model of human epithelial cancer
Journal: CANCER RES, 65 (12): 5317-5324 JUN 15 2005
Citations: 76
Authors: Kukowska-Latallo, JF;Candido, KA;Cao, ZY;Nigavekar, SS;Majoros, IJ;Thomas, TP;Balogh, LP;Khan, MK;Baker, JR
Addresses:
Univ Michigan, Hlth Syst, Ctr Biol Nanotechnol, 1150 W Med Ctr Dr,9220 MSRB3, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Dept Radiat Oncol, Ann Arbor, MI 48109 USA


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Label: Ballauff-2004
Title: Dendrimers in solution: Insight from theory and simulation
Journal: ANGEW CHEM INT ED, 43 (23): 2998-3020 2004
Citations: 70
Authors: Ballauff, M;Likos, CN
Addresses:
Univ Bayreuth, POB 101251, D-95440 Bayreuth, Germany
Univ Bayreuth, D-95440 Bayreuth, Germany
Univ Dusseldorf, Inst Theoret Phys 2, D-40225 Dusseldorf, Germany


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Label: Caminade-2004
Title: Nanomaterials based on phosphorus dendrimers
Journal: ACCOUNT CHEM RES, 37 (6): 341-348 JUN 2004
Citations: 59
Authors: Caminade, AM;Majoral, JP
Addresses:
CNRS, Chim Coordinat Lab, 205 Route Narbonne, F-31077 Toulouse 4, France
CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France


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Label: Dufes-2005
Title: Dendrimers in gene delivery
Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2177-2202 DEC 14 2005
Citations: 55
Authors: Dufes, C;Uchegbu, IF;Schatzlein, AG
Addresses:
Univ Glasgow, Beatson Labs, Canc Res UK Ctr Oncol & Appl Pharmacol, Glasgow G61 1BD, Lanark, Scotland
Univ Glasgow, Beatson Labs, Canc Res UK Ctr Oncol & Appl Pharmacol, Glasgow G61 1BD, Lanark, Scotland
Univ Strathclyde, Dept Pharmaceut Sci, Glasgow G4 0NR, Lanark, Scotland


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Label: Duncan-2005
Title: Dendrimer biocompatibility and toxicity
Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2215-2237 DEC 14 2005
Citations: 50
Authors: Duncan, R;Izzo, L
Addresses:
Univ Cardiff Wales, Welsh Sch Pharm, Ctr Polymer Therapeut, Cardiff CF10 3XF, Wales
Univ Cardiff Wales, Welsh Sch Pharm, Ctr Polymer Therapeut, Cardiff CF10 3XF, Wales
Univ Salerno, Dipartimento Chim, I-84081 Baronissi, SA, Italy


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Label: Chase-2004
Title: Where organometallics and dendrimers merge: the incorporation of organometallic species into dendritic molecules
Journal: J ORGANOMET CHEM, 689 (24): 4016-4054 Sp. Iss. SI NOV 29 2004
Citations: 49
Authors: Chase, PA;Gebbink, RJMK;van Koten, G
Addresses:
Univ Utrecht, Debye Inst, Dept Met Mediated Synth, Padualaan 8, NL-3584 CH Utrecht, Netherlands
Univ Utrecht, Debye Inst, Dept Met Mediated Synth, NL-3584 CH Utrecht, Netherlands


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Label: Majoros-2006
Title: PAMAM dendrimer-based multifunctional conjugate for cancer therapy: Synthesis, characterization, and functionality
Journal: BIOMACROMOLECULES, 7 (2): 572-579 FEB 2006
Citations: 48
Authors: Majoros, IJ;Myc, A;Thomas, T;Mehta, CB;Baker, JR
Addresses:
Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, 200 Zina Pitcher Pl,4027 Kresge 2, Ann Arbor, MI 48109 USA
Univ Michigan, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA


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Label: Delort-2004
Title: A strong positive dendritic effect in a peptide dendrimer-catalyzed ester hydrolysis reaction
Journal: J AM CHEM SOC, 126 (48): 15642-15643 DEC 8 2004
Citations: 43
Authors: Delort, E;Darbre, T;Reymond, JL
Addresses:
Univ Bern, Dept Chem & Biochem, Freiestr 3, CH-3012 Bern, Switzerland
Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland


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Label: Maiti-2005
Title: Effect of solvent and pH on the structure of PAMAM dendrimers
Journal: MACROMOLECULES, 38 (3): 979-991 FEB 8 2005
Citations: 41
Authors: Maiti, PK;Cagin, T;Lin, ST;Goddard, WA
Addresses:
CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA 91125 USA
CALTECH, Mat & Proc Simulat Ctr, Pasadena, CA 91125 USA


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Label: Kobayashi-2005
Title: Nano-sized MRI contrast agents with dendrimer cores
Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2271-2286 DEC 14 2005
Citations: 38
Authors: Kobayashi, H;Brechbiel, MW
Addresses:
NCI, Mol Imaging Program, Ctr Canc Res, NIH, Bldg 10,Room 1B40,10 Ctr Dr, Bethesda, MD 20892 USA
NCI, Mol Imaging Program, Ctr Canc Res, NIH, Bethesda, MD 20892 USA
NCI, Radiat Oncol Branch, Canc Res Ctr, NIH, Bethesda, MD 20892 USA


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Label: Patri-2005
Title: Targeted drug delivery with dendrimers: Comparison of the release kinetics of covalently conjugated drug and non-covalent drug inclusion complex
Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2203-2214 DEC 14 2005
Citations: 34
Authors: Patri, AK;Kukowska-Latallo, JF;Baker, JR
Addresses:
Nanotechnol Inst Med & Biol Sci, Div Clin Immunol & Allergy, Dept Internal Med, 9220 MSRB III, Ann Arbor, MI 48109 USA
Univ Michigan, Hlth Syst, Michigan Nanotechnol Inst Med & Biol Sci, Ann Arbor, MI 48109 USA


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Label: D'Emanuele-2005
Title: Dendrimer-drug interactions
Journal: ADVAN DRUG DELIVERY REV, 57 (15): 2147-2162 DEC 14 2005
Citations: 27
Authors: D'Emanuele, A;Attwood, D
Addresses:
Univ Manchester, Sch Pharm & Pharmaceut Sci, Oxford Rd, Manchester M13 9PL, Lancs, England
Univ Manchester, Sch Pharm & Pharmaceut Sci, Manchester M13 9PL, Lancs, England


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Label: Talanov-2006
Title: Dendrimer-based nanoprobe for dual modality magnetic resonance and fluorescence imaging
Journal: NANO LETT, 6 (7): 1459-1463 JUL 12 2006
Citations: 26
Authors: Talanov, VS;Regino, CAS;Kobayashi, H;Bernardo, M;Choyke, PL;Brechbiel, MW
Addresses:
NCI, Radioimmune & Inorgan Chem Sect, Radiat Oncol Branch, NIH,Mol Imaging Program, Bldg 10,Room 1B40,10 Ctr Dr, Bethesda, MD 20892 USA
NCI, Radioimmune & Inorgan Chem Sect, Radiat Oncol Branch, NIH,Mol Imaging Program, Bethesda, MD 20892 USA


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Label: Qiu-2006
Title: Polymer architecture and drug delivery
Journal: PHARMACEUT RES, 23 (1): 1-30 JAN 2006
Citations: 24
Authors: Qiu, LY;Bae, YH
Addresses:
Univ Utah, Dept Pharmaceut & Pharmaceut Chem, 421 Wakara Way,Suite 315, Salt Lake City, UT 84108 USA
Univ Utah, Dept Pharmaceut & Pharmaceut Chem, Salt Lake City, UT 84108 USA
Zhejiang Univ, Coll Pharmaceut Sci, Hangzhou 310031, Peoples R China


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Label: Darbre-2006
Title: Peptide dendrimers as artificial enzymes, receptors, and drug-delivery agents
Journal: ACCOUNT CHEM RES, 39 (12): 925-934 DEC 19 2006
Citations: 22
Authors: Darbre, T;Reymond, JL
Addresses:
Univ Bern, Dept Chem & Biochem, Freiestr 3, CH-3012 Bern, Switzerland
Univ Bern, Dept Chem & Biochem, CH-3012 Bern, Switzerland


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Label: Shabat-2006
Title: Self-immolative dendrimers as novel drug delivery platforms
Journal: J POLYM SCI A-POLYM CHEM, 44 (5): 1569-1578 MAR 1 2006
Citations: 22
Authors: Shabat, D
Addresses:
Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel
Tel Aviv Univ, Raymond & Beverly Sackler Fac Exact Sci, Sch Chem, IL-69978 Tel Aviv, Israel


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Label: Yang-2006
Title: Dendrimers for pharmaceutical and biomedical applications
Journal: J BIOMATER SCI-POLYM ED, 17 (1-2): 3-19 2006
Citations: 22
Authors: Yang, H;Kao, WYJ
Addresses:
Univ Wisconsin, Sch Pharm, 777 Highland Ave, Madison, WI 53705 USA
Univ Wisconsin, Sch Pharm, Madison, WI 53705 USA
Univ Wisconsin, Coll Engn, Dept Biomed Engn, Madison, WI 53705 USA


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Label: Lo-2007
Title: Development of dendrimers: Macromolecules for use in organic light-emitting diodes and solar cells
Journal: CHEM REV, 107 (4): 1097-1116 APR 2007
Citations: 11
Authors: Lo, SC;Burn, PL
Addresses:
Univ Oxford, Dept Chem, Chem Res Lab, 12 Mansfield Rd, Oxford OX1 3TA, England
Univ Oxford, Dept Chem, Chem Res Lab, Oxford OX1 3TA, England


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Label: Tomalia-2007
Title: Dendrimers as multi-purpose nanodevices for oncology drug delivery and diagnostic imaging
Journal: BIOCHEM SOC TRANS, 35: 61-67 Part 1 FEB 2007
Citations: 11
Authors: Tomalia, DA;Reyna, LA;Svenson, S
Addresses:
Dendrit Nanotechnol Inc, 2625 Denison Dr, Mt Pleasant, MI 48858 USA
Dendrit Nanotechnol Inc, Mt Pleasant, MI 48858 USA
Cent Michigan Univ, Dept Chem, Mt Pleasant, MI 48859 USA


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Label: Antoni-2007
Title: A chemoselective approach for the accelerated synthesis of well-defined dendritic architectures
Journal: CHEM COMMUN, (22): 2249-2251 JUN 14 2007
Citations: 9
Authors: Antoni, P;Nystrom, D;Hawker, CJ;Hult, A;Malkoch, M
Addresses:
Royal Inst Technol, Teknikringen S6-58, SE-10044 Stockholm, Sweden
Royal Inst Technol, SE-10044 Stockholm, Sweden
Univ Calif Santa Barbara, Mat Res Lab, Santa Barbara, CA 93106 USA


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Label: Chandrasekar-2007
Title: The development of folate-PAMAM dendrimer conjugates for targeted delivery of anti-arthritic drugs and their pharmacokinetics and biodistribution in arthritic rats
Journal: BIOMATERIALS, 28 (3): 504-512 JAN 2007
Citations: 8
Authors: Chandrasekar, D;Sistla, R;Ahmad, FJ;Khar, RK;Diwan, PV
Addresses:
Indian Inst Chem Technol, Div Pharmacol, Uppal Rd, Hyderabad 500007, Andhra Pradesh, India
Indian Inst Chem Technol, Div Pharmacol, Hyderabad 500007, Andhra Pradesh, India
Jamia Hamdard Deemed Univ, Fac Pharm, Dept Pharmaceut, New Delhi, India


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Label: Gingras-2007
Title: Cleavable dendrimers
Journal: ANGEW CHEM INT ED, 46 (7): 1010-1017 2007
Citations: 8
Authors: Gingras, M;Raimundo, JM;Chabre, YM
Addresses:
Univ Nice, Fac Sci, Inst Chem, 28 Av Valrose, F-06108 Nice 2, France
Univ Nice, Fac Sci, Inst Chem, F-06108 Nice 2, France


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Label: Paleos-2007
Title: Molecular engineering of dendritic polymers and their application as drug and gene delivery systems
Journal: MOL PHARM, 4 (2): 169-188 MAR-APR 2007
Citations: 8
Authors: Paleos, CM;Tsiourvas, D;Sideratou, Z
Addresses:
NCSR Demokritos, Inst Phys Chem, Aghia Paraskevi 15310, Attiki, Greece
NCSR Demokritos, Inst Phys Chem, Aghia Paraskevi 15310, Attiki, Greece


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Keywords: DRUG DELIVERY APPLICATIONS; TARGETED DRUG DELIVERY; NOVEL DRUG DELIVERY PLATFORMS; ONCOLOGY DRUG DELIVERY; PAMAM DENDRIMERS.



Top Topics : 2008 : Jun. 08 - NOVEL DRUG DELIVERY PLATFORMS WITH DENDRIMERS - Research Front Map