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Top Topics Research Front Map - February 2010

As part of this bimonthly processing, ScienceWatch.com selects the Research Fronts with the largest absolute increase in size in each of the 22 major fields covered by Essential Science IndicatorsSM from Thomson Reuters. The size of a research front is determined by the number of core papers it contains. This Research Front on MYELOID SUPPRESSOR CELLS IN CANCER from the field of Immunology was selected for mapping from the list of Top Topics for February 2010 (data from the fifth bimonthly period of 2009). The map is a diagrammatic representation of the 16 core papers comprising the front in Immunology.

Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together). Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in pink. Annotations may have been added to this map which represent the main research themes. These appear as labels attached to specific regions on the maps. Rodriguez-2004 Zea-2005 Bronte-2005 Kusmartsev-2006 Huang-2006 Serafini-2006 Gallina-2006 Sica-2007 Sinha-2007 Nagaraj-2007 Pan-2008 Movahedi-2008 Cheng-2008 Gabrilovich-2009 Ozao-Choy-2009 Ko-2009

 

MYELOID SUPPRESSOR CELLS IN CANCER

 


 Core Papers 


Label: Bronte-2005
Title: Regulation of immune responses by L- arginine metabolism
Journal: NAT REV IMMUNOL, 5 (8): 641-654 AUG 2005
Citations: 163
Authors: Bronte, V;Zanovello, P
Addresses:
Univ Padua, Dept Oncol & Surg Sci, Canc Ctr Veneto Reg, Via Gattamelata 64, Padua, Italy
Univ Padua, Dept Oncol & Surg Sci, Canc Ctr Veneto Reg, Padua, Italy


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Label: Serafini-2006
Title: Myeloid suppressor cells in cancer: Recruitment, phenotype, properties, and mechanisms of immune suppression
Journal: SEMIN CANCER BIOL, 16 (1): 53-65 FEB 2006
Citations: 146
Authors: Serafini, P;Borrello, I;Bronte, V
Addresses:
Univ Padua, Dept Oncol & Surg Sci, Via Gattamelata 64, I-35121 Padua, Italy
Univ Padua, Dept Oncol & Surg Sci, I-35121 Padua, Italy
Johns Hopkins, Sidney Kimmel Coprehens Canc Ctr, Baltimore, MD USA


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Label: Gallina-2006
Title: Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8(+) T cells
Journal: J CLIN INVEST, 116 (10): 2777-2790 OCT 2006
Citations: 135
Authors: Gallina, G;Dolcetti, L;Serafini, P;De Santo, C;Marigo, I;Colombo, MP;Basso, G;Brombacher, F;Borrello, I;Zanovello, P;Bicciato, S;Bronte, V
Addresses:
Ist Oncol Veneto, Via Gattamelata 64, I-35128 Padua, Italy
Ist Oncol Veneto, I-35128 Padua, Italy
Johns Hopkins, Sidney Kimmel Comprehens Canc Ctr, Baltimore, MD USA
Ist Nazl Tumori, Dept Expt Oncol, Immunotherapy & Gene Therapy Unit, I-20133 Milan, Italy
Univ Padua, Dept Pediat, Padua, Italy
Univ Cape Town, Inst Infect Dis & Mol Med, ZA-7925 Cape Town, South Africa
Univ Padua, Dept Oncol & Surg Sci, Oncol Sect, Padua, Italy
Univ Padua, Dept Chem Engn Proc, Padua, Italy


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Label: Zea-2005
Title: Arginase-producing myeloid suppressor cells in renal cell carcinoma patients: A mechanism of tumor evasion
Journal: CANCER RES, 65 (8): 3044-3048 APR 15 2005
Citations: 128
Authors: Zea, AH;Rodriguez, PC;Atkins, NB;Hernandez, C;Signoretti, S;Zabaleta, J;McDermott, D;Quiceno, D;Youmans, A;O'Neill, A;Mier, J;Ochoa, AC
Addresses:
Louisiana State Univ, Hlth Sci Ctr, Stanley Scott Canc Ctr, Dept Immunol & Microbiol, New Orleans, LA 70112 USA
Louisiana State Univ, Hlth Sci Ctr, Stanley Scott Canc Ctr, Dept Immunol & Microbiol, New Orleans, LA 70112 USA
Louisiana State Univ, Hlth Sci Ctr, Stanley Scott Canc Ctr, Dept Pediat, New Orleans, LA 70112 USA
Louisiana State Univ, Hlth Sci Ctr, Stanley Scott Canc Ctr, Dept Pathol, New Orleans, LA 70112 USA
Harvard Univ, Dana Farber Canc Ctr, Renal Canc Program, Boston, MA 02115 USA


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Label: Rodriguez-2004
Title: Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
Journal: CANCER RES, 64 (16): 5839-5849 AUG 15 2004
Citations: 123
Authors: Rodriguez, PC;Quiceno, DG;Zabaleta, J;Ortiz, B;Zea, AH;Piazuelo, MB;Delgado, A;Correa, P;Brayer, J;Sotomayor, EM;Antonia, S;Ochoa, JB;Ochoa, AC
Addresses:
Louisiana State Univ, Hlth Sci Ctr, Stanley S Scott Canc Ctr, Tumor Immunol Program, 533 Bolivar St,455, New Orleans, LA 70112 USA
Louisiana State Univ, Hlth Sci Ctr, Stanley S Scott Canc Ctr, Tumor Immunol Program, New Orleans, LA 70112 USA
Louisiana State Univ, Hlth Sci Ctr, Dept Pathol, New Orleans, LA 70112 USA
Louisiana State Univ, Hlth Sci Ctr, Dept Pediat, New Orleans, LA 70112 USA
Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33620 USA
Univ S Florida, Inst Res, Tampa, FL 33620 USA
Univ Pittsburgh, Dept Surg, Pittsburgh, PA 15260 USA


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Label: Huang-2006
Title: Gr-1(+)CD115(+) immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
Journal: CANCER RES, 66 (2): 1123-1131 JAN 15 2006
Citations: 120
Authors: Huang, B;Pan, PY;Li, QS;Sato, AI;Levy, DE;Bromberg, J;Divino, CM;Chen, SH
Addresses:
Mt Sinai Sch Med, Dept Gene & Cell Med, Box 1496,1 Gustave L Levy Pl, New York, NY 10020 USA
Mt Sinai Sch Med, Dept Gene & Cell Med, New York, NY 10020 USA
Mt Sinai Sch Med, Dept Gen Surg, New York, NY USA
NYU, Sch Med, Dept Pathol & Microbiol, New York, NY USA


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Label: Sica-2007
Title: Altered macrophage differentiation and immune dysfunction in tumor development
Journal: J CLIN INVEST, 117 (5): 1155-1166 MAY 2007
Citations: 106
Authors: Sica, A;Bronte, V
Addresses:
Ist Oncol Veneto, IRCCS, Via Gattamelata 64, I-35128 Padua, Italy
Ist Oncol Veneto, IRCCS, I-35128 Padua, Italy
IRCCS, Ist Clin Humanitas, Rozzano, Italy


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Label: Kusmartsev-2006
Title: Role of immature myeloid cells in mechanisms of immune evasion in cancer
Journal: CANCER IMMUNOL IMMUNOTHER, 55 (3): 237-245 MAR 2006
Citations: 71
Authors: Kusmartsev, S;Gabrilovich, DI
Addresses:
Univ S Florida, H Lee Moffitt Canc Ctr & Res Inst, MRC 2067,12902 Magnolia, Tampa, FL 33612 USA
Univ S Florida, H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA
Univ S Florida, Dept Interdisciplinary Oncol, Tampa, FL 33612 USA


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Label: Nagaraj-2007
Title: Altered recognition of antigen is a mechanism of CD8(+) T cell tolerance in cancer
Journal: NATURE MED, 13 (7): 828-835 JUL 2007
Citations: 69
Authors: Nagaraj, S;Gupta, K;Pisarev, V;Kinarsky, L;Sherman, S;Kang, L;Herber, DL;Schneck, J;Gabrilovich, DI
Addresses:
Univ S Florida, H Lee Moffitt Canc Ctr, 12902 Magnolia Dr, Tampa, FL 33647 USA
Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33647 USA
Johns Hopkins Univ, Sch Med, Baltimore, MD 21205 USA
Univ Nebraska Med Ctr, Omaha, NE 68198 USA
Eppley Canc Ctr, Omaha, NE 68198 USA


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Label: Sinha-2007
Title: Prostaglandin E2 promotes tumor progression by inducing myeloid-derived suppressor cells
Journal: CANCER RES, 67 (9): 4507-4513 MAY 1 2007
Citations: 49
Authors: Sinha, P;Clements, VK;Fulton, AM;Ostrand-Rosenberg, S
Addresses:
Univ Maryland Baltimore Cty, Dept Biol Sci, 1000 Hilltop Circle, Baltimore, MD 21250 USA
Univ Maryland Baltimore Cty, Dept Biol Sci, Baltimore, MD 21250 USA
Univ Maryland, Dept Pathol, College Pk, MD 20742 USA
Univ Maryland, Stewart Greenebaum Ctr Ctr, College Pk, MD 20742 USA


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Label: Movahedi-2008
Title: Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity
Journal: BLOOD, 111 (8): 4233-4244 APR 15 2008
Citations: 30
Authors: Movahedi, K;Guilliams, M;Van den Bossche, J;Van den Bergh, R;Gysemans, C;Beschin, A;De Baetselier, P;Van Ginderachter, JA
Addresses:
Vrije Univ Brussels, Cellular & Mol Immunol Lab, Bldg E,Level 8,Pleinlaan 2, B-1050 Brussels, Belgium
Vrije Univ Brussels, Cellular & Mol Immunol Lab, B-1050 Brussels, Belgium
VIB, Dept Mol & Cellular Interact, Cellular & Mol Immunol Lab, Brussels, Belgium
Katholieke Univ Leuven, Dept Expt Med, Lab Expt Med & Endocrinol, Louvain, Belgium


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Label: Cheng-2008
Title: Inhibition of dendritic cell differentiation and accumulation of myeloid-derived suppressor cells in cancer is regulated by S100A9 protein
Journal: J EXP MED, 205 (10): 2235-2249 SEP 29 2008
Citations: 24
Authors: Cheng, PY;Corzo, CA;Luetteke, N;Yu, B;Nagaraj, S;Bui, MM;Ortiz, M;Nacken, W;Sorg, C;Vogl, T;Roth, J;Gabrilovich, DI
Addresses:
Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33612 USA
Univ S Florida, H Lee Moffitt Canc Ctr, Tampa, FL 33612 USA
Univ Munster, Inst Immunol, D-48149 Munster, Germany
Ctr Mol Biol Inflammat, Inst Mol Virol, D-48149 Munster, Germany


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Label: Pan-2008
Title: Reversion of immune tolerance in advanced malignancy: modulation of myeloid-derived suppressor cell development by blockade of stem-cell factor function
Journal: BLOOD, 111 (1): 219-228 JAN 1 2008
Citations: 24
Authors: Pan, PY;Wang, GX;Yin, BJ;Ozao, J;Ku, T;Divino, CM;Chen, SH
Addresses:
Mt Sinai Sch Med, Dept Genet & Cell Med, Box 1496,1 Gustave L Levy Pl, New York, NY 10029 USA
Mt Sinai Sch Med, Dept Genet & Cell Med, New York, NY 10029 USA
Mt Sinai Sch Med, Dept Gen Surg, New York, NY 10029 USA


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Label: Gabrilovich-2009
Title: Myeloid-derived suppressor cells as regulators of the immune system
Journal: NAT REV IMMUNOL, 9 (3): 162-174 MAR 2009
Citations: 18
Authors: Gabrilovich, DI;Nagaraj, S
Addresses:
Univ S Florida, H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA
Univ S Florida, H Lee Moffitt Canc Ctr & Res Inst, Tampa, FL 33612 USA
Univ S Florida, Dept Oncol Sci, Tampa, FL 33612 USA


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Label: Ko-2009
Title: Sunitinib Mediates Reversal of Myeloid-Derived Suppressor Cell Accumulation in Renal Cell Carcinoma Patients
Journal: CLIN CANCER RES, 15 (6): 2148-2157 MAR 15 2009
Citations: 8
Authors: Ko, JS;Zea, AH;Rin, BI;Ireland, JL;Elson, P;Cohen, P;Golshayan, A;Rayman, PA;Wood, L;Garcia, J;Dreicer, R;Bukowski, R;Finke, JH
Addresses:
Cleveland Clin Fdn, Lerner Res Inst, Dept Immunol, Cleveland Clin, NE4-250,9500 Euclid Ave, Cleveland, OH 44195 USA
Cleveland Clin Fdn, Lerner Res Inst, Dept Immunol, Cleveland Clin, Cleveland, OH 44195 USA
Case Western Reserve Univ, Dept Pathol, Cleveland, OH 44106 USA
Cleveland Clin, Taussig Canc Inst, Cleveland, OH 44106 USA
Cleveland Clin, Glickman Urol Inst, Cleveland, OH 44106 USA
Cleveland Clin, Quantitat Hlth Sci Dept, Cleveland, OH 44106 USA
Louisiana State Univ, Hlth Sci Ctr, Stanley S Scott Canc Ctr, Dept Microbiol, New Orleans, LA USA


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Label: Ozao-Choy-2009
Title: The Novel Role of Tyrosine Kinase Inhibitor in the Reversal of Immune Suppression and Modulation of Tumor Microenvironment for Immune-Based Cancer Therapies
Journal: CANCER RES, 69 (6): 2514-2522 MAR 15 2009
Citations: 6
Authors: Ozao-Choy, J;Ma, G;Kao, J;Wang, GX;Meseck, M;Sung, M;Schwartz, M;Divino, CM;Pan, PY;Chen, SH
Addresses:
Mt Sinai Sch Med, Dept Gene & Cell Med, Box 1496 1 Gustave L Levy Pl, New York, NY 10029 USA
Mt Sinai Sch Med, Dept Gene & Cell Med, New York, NY 10029 USA
Mt Sinai Sch Med, Dept Gen Surg, New York, NY USA
Mt Sinai Sch Med, Dept Radiat Oncol, New York, NY USA
Mt Sinai Sch Med, Dept Med, Div Hematol Oncol, New York, NY USA


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KEYWORDS: GR-1(+)CD115(+) IMMATURE MYELOID SUPPRESSOR CELLS MEDIATE; INDUCING MYELOID-DERIVED SUPPRESSOR CELLS; MYELOID-DERIVED SUPPRESSOR CELL DEVELOPMENT; DISCRETE TUMOR-INDUCED MYELOID-DERIVED SUPPRESSOR CELL SUBPOPULATIONS.
[8927 (2003-2009_5) (CLI/imm: TT, Feb 2010)]

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