|
|
 Penn’s
Virginia M.-Y. Lee
on Neurodegenerative Disease
The
diseases are different, but the pathologies are surprisingly similar.
At the pathological core of Alzheimer’s
disease, Parkinson’s disease, and perhaps a half-dozen other
neurodegenerative disorders and dementias are misfolded proteins that
gradually accumulate within the brain—the amyloid plaques or
neurofibrillary tangles of Alzheimer’s disease, for instance, and
the Lewy bodies of Parkinson’s. These pathologies develop
insidiously over years or decades, and can manifest themselves
clinically as dementia, memory loss, and movement disorders. Exactly
how and why this happens, however, remains among the most pressing
questions in all of neuroscience.
The past decade has seen a revolution in the understanding of the
common pathogenic mechanisms at the heart of these neurodegenerative
diseases. Among the leaders of this revolution has been the University
of Pennsylvania neuroscientist...read•> |
|
 |
![University of California [UC] at Berkeley](berkely.gif) Harvard,
Stanford, Berkeley: Top Trio in "Top Ten" Finale
This
is the second of two installments in the latest "Top Ten" roundup of
U.S. university research in 21 main fields, as measured by the citation impact
of research papers published by the top 100 federally funded universities
between 2001 and 2005 and cited during the same period. This
second part features 12 listings in the physical and social sciences.
|
|
JAK2 Mutation Probed
in Myoproliferative Disorders |
The New Buckyball?
Graphene
Papers Popping Up in Physics |
Liquid-Solid-Solution:
It’s LSS For Nanocrystal
Synthesis |
Motifs in Gene Regulation,
Conserved Across
Species |
|
The Research Services
Group
of Thomson Scientific.
 |
|
|
.
