The
Hottest Research of 1999-2000
  cientists who, as of late 2000, had published the greatest number of highly cited papers over the past two years, according to the latest update of ISI's Hot Papers database. The table on page 2 lists the papers published in 2000 (excluding reviews) that were most cited by year's end. The sole name at #1 on the list of scientists seems quite fitting, given his wide public visibility in 2000:
J. Craig Venter of Celera Genomics and The Institute for Genomic Research (TIGR), Rockville, Maryland. In addition to his highly publicized role in the effort to sequence the human genome, Venter had a hand in seven recent Hot Papers. His labors last year....
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 St. Jude's Martine Roussel Answers the Call of
ARF
The line between normal cell growth and cancer is patrolled by an intricate mosaic of stimuli and regulators.
Proto-oncogenes push the cell cycle toward proliferation and tumor-suppressor genes put the brakes on proliferation and, if necessary, nudge the cell into suicide. Over the past two decades, biologists have made remarkable progress in unraveling the intricate checks and balances that operate on cellular growth. Among the most intriguing of these tumor suppressors is one known as ARF, discovered in 1997 in the laboratory of Charles J. Sherr and Martine F. Roussel at St. Jude Children's Research Hospital in Memphis, Tennessee. ARF acts as a crucial genetic circuit breaker to stop cells from progressing down the road to
cancer
Since ARF's discovery, biomedical researchers have had considerable
interest in this tumor suppressor. In one two-month period in late
1999, four papers on ARF by the Sherr/Roussel
collaboration racked up...
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