

The Red Hot Research Papers of 1997
| Rank |
Paper |
Citations |
| 1 |
J. Yang, et al., "Prevention
of apoptosis by Bcl-2: Release ofcytochrome c from mitochondria blocked," Science,
275(5303):1129-32, 21 February 1997. |
56 |
| 2 |
R.M. Kluck, et al., "The
release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of
apoptosis," Science, 275(5303):1132-6, 21 February 1997. |
55 |
| 3 |
T.R. Franke, et al., "Direct
regulation of the Akt proto-oncogene product by phosphatidylinositol-3,
4-bisphosphate," Science, 275(5300):665-8, 31 January 1997. |
54 |
| 4 |
O. Zhuchenko, et al., "Autosomal
dominant cerebellar ataxia (SCA6) associated with small polyglutamine expansions in the a1A-voltage-dependent
calcium channel," Nature Genetics, 15(1):62-9, January 1997. |
47 |
| 5 |
R. Scully, et al., "Association
of BRCA1 with Rad51 in mitotic and meiotic cells," Cell,
88(2):265-75, 24 January 1997. |
46 |
| 6 |
H. Dudek, et al., "Regulation
of neuronal survival by the serine-threonine protein kinase Akt," Science,
275(5300):661-5, 31 January 1997. |
41 |
| 7 |
A.M. Chinnaiyan, et al., "Interaction
of CED-4 with CED-3 and CED-9: a molecular framework for cell death," Science,
275(5303):1122-6, 21 February 1997. |
40 |
| 8 |
A. Kauffmann-Zeh, et al., "Suppression
of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB," Nature,
385(6616):544-8, 6 February 1997. |
40 |
| 9 |
M. Citron, et al., "Mutant
presenilins of Alzheimer's disease increase production of 42-residue amyloid b-protein in both transfected
cells and transgenic mice," Nature Medicine, 3(1):67-72, January
1997. |
38 |
| 10 |
I. Wilmut, et al., "Viable
offspring derived from fetal and adult mammalian cells," Nature,
385(6619):810-3, 27 February 1997. |
37 |
| 11 |
A.J. Minn, et al., "Bcl-XL
forms an ion channel in synthetic lipid membranes," Nature,
385(6614):353-7, 23 January 1997. |
35 |
| 12 |
W. Fan, et al., "Role of
melanocortinergic neurons in feeding and the agouti obesity syndrome," Nature,
385(6612):165-8, 9 January 1997. |
34 |
| 13 |
J. Li, et al., "PTEN, a
putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate
cancer," Science, 275(5308):1943-7, 28 March 1997. |
33 |
| 14 |
C. Fleury, et al., "Uncoupling
protein-2: a novel gene linked to obesity and hyperinsulinemia," Nature
Genetics, 15(3):269-72, March 1997. |
33 |
| 15 |
D.G. Julian, et al., "Randomised
trial of effect of amiodarone on mortality in patients with left-ventricular dysfunction
after recent myocardial infarction: EMIAT," The Lancet,
349(9053):667-74, 8 March 1997. |
32 |
| 16 |
W. Xu, S.C. Harrison, M.J. Eck, "Three-dimensional
structure of the tyrosine kinase c-Src," Nature, 385(6617):595-602,13
February 1997. |
31 |
| 17 |
P.A. Steck, et al., "Identification
of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in
multiple advanced cancers," Nature Genetics, 15(4):356-62, April
1997. |
30 |
| 18 |
J.A. Cairns, et al., "Randomised
trial of outcome after myocardial infarction in patients with frequent or repetitive
ventricular premature depolarisations: CAMIAT," The Lancet,
349(9053):675-82,8 March 1997. |
30 |
| 19 |
P.J. Morin, et al., "Activation
of b-catenin-Tcf signaling in colon cancer by mutations in b-catenin or APC,"
Science, 275(5307):1787-90, 21 March 1997. |
29 |
| 20 |
H.J. Alter, et al., "The
incidence of transfusion-associated hepatitis G virus infection and its relation to liver
disease," New Engl. J. Med., 336(11):747-54, 13 March 1997. |
29 |
| 21 |
D. Wu, H.D. Wallen, G. Nuñez, "Interaction
and regulation of subcellular localization of CED-4 by CED-9," Science,
275(5303):1126-9, 21 February 1997. |
29 |
| 22 |
C.C. Bradley, C.A. Sackett, R.G. Hulet, "Bose-Einstein
condensation of lithium: Observation of limited condensate number," Phys.
Rev. Lett., 78(6):985-9, 10 February 1997. |
29 |
| 23 |
M.R. Andrews, et al., "Observation
of interference between two Bose condensates," Science,
275(5300):637-41, 31 January 1997. |
29 |
| 24 |
D. Huszar, et al., "Targeted
disruption of the melanocortin-4 receptor results in obesity in mice," Cell,
88(1):131-41, 10 January 1997. |
29 |
| 25 |
B. Rubinfeld, et al., "Stabilization
of b-catenin by
genetic defects in melanoma cell lines," Science, 275(5307):1790-2,
21 March 1997. |
28 |
| 26 |
M.P. Lee, et al., "Human
KVLQT1 gene shows tissue-specificimprinting and encompasses Beckwith-Wiedemann syndrome
chromosomal rearrangements," Nature Genetics, 15(2):181-5, February
1997. |
28 |
| 27 |
V. Korinek, et al., "Constitutive
transcriptional activation by a b-catenin-Tcf complex in APC-/- colon carcinoma,"
Science, 275(5307):1784-7, 21 March 1997. |
27 |
| 28 |
G.G.J.M. Kuiper, et al., "Comparison
of the ligand binding specificity and transcript tissue distribution of estrogen receptors
a and b," Endocrinology,
138(3):863-70, March 1997. |
27 |
| 29 |
F.S. Lee, et al., "Activation
of the Ikba kinase
complex by MEKK1, a kinase of the JNK pathway," Cell, 88(2):213-22,
24 January 1997. |
27 |
| 30 |
R. Mahajan, et al., "A
small ubiquitin-related polypeptide involved in the targeting RanGAP1 to nuclear pore
complex protein RanBP2," Cell, 88(1):97-107, 10 January 1997. |
27 |
| 31 |
H. Nielsen, et al.,
"Identification of prokaryotic and eukaryotic signal peptides and prediction of their
cleavage sites," Protein Eng., 10(1):1-6, January 1997. |
27 |
| 32 |
M. Groll, et al., "Structure
of 20S proteasome from yeast at 2.4 Å resolution," Nature,
386(6624):463-71, 3 April 1997. |
26 |
| 33 |
N.L. Michael, et al., "The
role of viral phenotype and CCR-5 gene defects in HIV-1 transmission and disease
progression," Nature Medicine, 3(3):338-40, March 1997. |
26 |
| 34 |
B. Pitt, et al., "Randomised
trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of
Losartan in the Elderly Study, ELITE)," The Lancet,
349(9054):747-52, 15 March 1997. |
26 |
| 35 |
J.F. Bazan,et al., "A
new class of membrane-bound chemokine with a CX3C motif," Nature,
385(6617):640-4, 13 February 1997. |
26 |
| 36 |
M. Sano, et al., "A
controlled trial of selegiline, alpha-tocopherol, or both as treatment for Alzheimer's
disease," New Engl. J. Med., 336(17):1216-22, 24 April 1997. |
25 |
| 37 |
T. Banks, et al., "M
theory as a matrix model: a conjecture," Phys. Rev. D,
55(8):5112-28, 15 April 1997. |
25 |
| 38 |
J. He, "CCR3 and CCR5 are
co-receptors for HIV-1 infection of microglia," Nature,
385(6617):645-9, 13 February 1997. |
25 |
| 39 |
F. Sicheri, I. Moarefi, J. Kuriyan, "Crystal
structure of the Src family tyrosine kinase Hck," Nature,
385(6617):602-9, 13 February 1997. |
25 |
| 40 |
H.L. Lai, et al., "Improved
parton distributions from global analysis of recent deep inelastic scattering and
inclusive jet data," Phys. Rev. D, 55(3):1280-96, 1 February 1997. |
25 |
SOURCE: ISI'S Hot Papers
Database |
|