

The Red Hot Research Papers of 1998
| Rank |
Paper |
Citations |
| 1 |
M. Enari, et al., "A
caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD,"
Nature, 391(6662):43-50, 1 January 1998. |
112 |
| 2 |
A.G. Bodnar, et al., "Extension
of life-span by introduction of telomerase into normal human cells," Science,
279(5349):349-52, 16 January 1998. |
89 |
| 3 |
D.A. Doyle, et al., "The
structure of the potassium channel: Molecular basis of K+ conduction and
selectivity," Science, 280(5360):69-77, 3 April 1998. |
76 |
| 4 |
H. Sakahira, M. Enari, S. Nagata, "Cleavage
of CAD inhibitor in CAD activation and DNA degradation during apoptosis," Nature,
391(6662):96-9, 1 January 1998. |
54 |
| 5 |
T. Weber, et al., "SNAREpins:
Minimal machinery for membrane fusion," Cell, 92(6):759-72, 20 March 1998.
|
45 |
| 6 |
R.O. Estacio, et al., "The
effect of nisoldipine as compared with enalapril on cardiovascular outcomes in patients
with non-insulin-dependent diabetes and hypertension," New Engl. J. Med.,
338(10):645-52, 5 March 1998. |
43 |
| 7 |
A. Brehm, et al., "Retinoblastoma
protein recruits histone deacetylase to repress transcription," Nature,
391(6667):597-601, 5 February 1998. |
41 |
| 8 |
F.J. Palella, et al., "Declining
morbidity and mortality among patients with advanced human immunodeficiency virus
infection," New Engl. J. Med., 338(13):853-60, 26 March 1998. |
39 |
| 9 |
V.M. Braud, et al., "HLA-E
binds to natural killer cell receptors CD94/NKG2A, B and C," Nature,
391(6669):795-9, 19 February 1998. |
39 |
| 10 |
L. Magnaghi-Jaulin, et al., "Retinoblastoma
protein represses transcription by recruiting a histone deacetylase," Nature,
391(6667):601-5, 5 February 1998. |
39 |
| 11 |
S.L. Rogers, et al., "A 24-week
double-blind, placebo-controlled trial of donepezil in patients with Alzheimers
disease," Neurology, 50(1):136-45, January 1998. |
38 |
| 12 |
Y. Zhang, Y. Xiong, W.G. Yarbrough, "ARF
promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both
the Rb and p53 tumor suppression pathways," Cell, 92(6):725-34, 20 March
1998. |
37 |
| 13 |
J. Pomerantz, et al., "The Ink4a
tumor suppressor gene product, p19Arf , interacts with MDM2 and neutralizes
MDM2s inhibition of p53," Cell, 92(6):713-23, 20 March 1998. |
36 |
| 14 |
S. Doublié, et al., "Crystal
structure of a bacteriophage T7 DNA replication complex at 2.2 Å resolution," Nature,
391(6664):251-8, 15 January 1998. |
35 |
| 15 |
R.J. Lin, et al., "Role of the
histone deacetylase complex in acute promyelocytic leukaemia," Nature,
391(6669):811-4, 19 February 1998. |
34 |
| 16 |
T. Rossé, et al., "Bcl-2
prolongs cell survival after Bax-induced release of cytochrome c," Nature,
391(6666):496-9, 29 January 1998. |
34 |
| 17 |
G. Pan, K. ORourke, V.M. Dixit, "Caspase-9,
Bcl-XL, and Apaf-1 form a ternary complex," J. Biol. Chem.,
273(10):5841-5, 6 March 1998. |
32 |
| 18 |
R. Bonecchi, et al., "Differential
expression of chemokine receptors and chemotactic responsiveness of Type 1 T helper cells
(Th1s) and Th2s," J. Exp. Med., 187(1):129-34, 5 January 1998. 32 |
|
| 19 |
M. Ricote, et al., "The
peroxisome proliferator-activated receptor-g is a negative regulator of macrophage activation," Nature,
391(6662):79-82, 1 January 1998. 32 |
|
| 20 |
E. Korzus, et al., "Transcription
factor-specific requirements for coactivators and their acetyltransferase functions,"
Science, 279(5351):703-7, 30 January 1998. |
31 |
| 21 |
F. Grignani, et al., "Fusion
proteins of the retinoic acid receptor-a A recruit histone deacetylase in promyelocytic leukaemia,"
Nature, 391(6669):815-8, 19 February 1998. |
30 |
| 22 |
L. Hansson, et al., "Effects of
intensive blood-pressure lowering and low-dose aspirin in patients with hypertension:
Principal results of the Hypertension Optimal Treatment (HOT) randomised trial," The
Lancet, 351(9118):1755-62, 13 June 1998. |
29 |
| 23 |
S.T. Cole, et al., "Deciphering
the biology of Mycobacterium tuberculosis from the complete genome sequence,"
Nature, 393(6685):537-44, 11 June 1998. |
29 |
| 24 |
S. Nakamura, et al., "InGaN/GaN/AIGaN-based
laser diodes with modulation-doped strained-layer superlattices grown on an epitaxially
laterally overgrown GaN substrate," Appl. Phys. Lett., 72(2):211-3, 12
January 1998. |
29 |
| 25 |
P. Tatti, et al., "Outcome
results of the Fosinopril Versus Amlodipine Cardiovascular Events Randomized Trial (FACET)
in patients with hypertension and NIDDM," Diabetes Care, 21(4):597-603,
April 1998. |
28 |
| 26 |
K.C. Garcia, et al., "Structural
basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen,"
Science, 279(5354):1166-72, 20 February 1998. |
28 |
| 27 |
K. Murali-Krishna, et al., "Counting
antigen-specific CD8 T cells: a reevaluation of bystander activation during viral
infection," Immunity, 8(2):177-87, 2 February 1998. |
28 |
| 28 |
G.S. Ogg, et al., "Quantitation
of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA," Science,
279(5359):2103-6, 27 March 1998. |
27 |
| 29 |
C. Scaffidi, et al., "Two CD95
(APO-1/Fas) signaling pathways," EMBO J., 17(6):1675-87, 16 March 1998. |
26 |
| 30 |
S. Igarishi, et al., "Suppression
of aggregate formation and apoptosis by transglutaminase inhibitors in cells expressing
truncated DRPLA protein with an expanded polyglutamine stretch," Nature
Genetics, 18(2):111-7, February 1998. |
26 |
| 31 |
C. Jiang, A.T. Ting, B. Seed, "PPAR-g agonists inhibit production
of monocyte inflammatory cytokines," Nature, 391(6662):82-6, 1 January
1998. |
26 |
| 32 |
H. Yasuda, et al., "Osteoclast
differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory
factor and is identical to TRANCE/RANKL," Proc. Natl. Acad. Sci. USA,
95(7):3597-3602, March 1998. |
25 |
| 33 |
M.L. Albert, B. Sautier, N. Bhardwaj, "Dendritic
cells acquire antigen from apoptotic cells and induce class I-restricted CTLs," Nature,
392(6671):86-9, 5 March 1998. |
25 |
| 34 |
M. Tanaka, et al., "Downregulation
of Fas ligand by shedding," Nature Medicine, 4(1):31-6, January 1998.
|
25 |
SOURCE: ISI'S Hot Papers
Database |
|