HHMI's Patrick O. Brown Muses on Microarrays
To say that DNA microarrays are hot is a bit of an understatement. Few technologies have ever exploded so quickly into biology, or had the potential to so dramatically increase our understanding of life. From every imaginable corner of biomedicine, researchers are turning to microarrays to take snapshots of the expression of thousands of genes at one time. They're watching how gene expression changes between cells, or as a cell grows or becomes infected or cancerous or simply old—and they're thinking up new uses with every passing day.
Microarrays have been around since the early 1990s, but the necessary equipment to use the technology could set back a laboratory nearly $200,000. Then Patrick O. Brown of the Howard Hughes Medical Institute, and his colleagues at Stanford University, published their first paper in Science in 1995...
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Vital Statistics on the Numbers Game
While unable to determine how many of the minds involved are actually
beautiful (although most are, no doubt, perfectly presentable), Science Watch
offers here a survey of mathematics research over the last 10 years. Highly
cited institutions (on the next page)
are ranked both by citations (left column) and
citation impact (that is, citations per paper, at right). Highly cited authors
also appear...
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