Science Watch® - Tracking Trends and Performance in Basic Research
Patrick O. BrownHHMI's Patrick O. Brown Muses on Microarrays
T
o say that DNA microarrays are hot is a bit of an understatement. Few technologies have ever exploded so quickly into biology, or had the potential to so dramatically increase our understanding of life. From every imaginable corner of biomedicine, researchers are turning to microarrays to take snapshots of the expression of thousands of genes at one time. They're watching how gene expression changes between cells, or as a cell grows or becomes infected or cancerous or simply old—and they're thinking up new uses with every passing day.
   Microarrays have been around since the early 1990s, but the necessary equipment to use the technology could set back a laboratory nearly $200,000. Then Patrick O. Brown of the Howard Hughes Medical Institute, and his colleagues at Stanford University, published their first paper in Science in 1995...Read the story
Vital Statistics on the Numbers Game
While unable to determine how many of the minds involved are actually beautiful (although most are, no doubt, perfectly presentable), Science Watch offers here a survey of mathematics research over the last 10 years. Highly cited institutions (on the next page) are ranked both by citations (left column) and citation impact (that is, citations per paper, at right). Highly cited authors also appear...Read the story

Medicine
Topoisomerase Inhibitors Add to Anti-Cancer Arsenal
Physics
Pellets to Wires: Physicists Making Much of MgB2
Chemistry
Liquid Helium Gets the Drop on Other Spectroscopy Schemes
Biology
Vaccine Boost From Insights Into Toll-Like Receptor #9?


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Science Watch®, May/June 2002, Vol. 13, No. 3
Citing URL: http://www.sciencewatch.com/jan-feb2002/index.html

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