Once again Science Watch takes its annual look back at the
hottest of recent research. Below in
table 1
are the researchers who, according to citations recorded during
2009, posted the highest numbers of Hot Papers published over the
preceding two years.
Table
2 (also below) lists the papers published in 2009 that were
most cited by year’s end.
Read
ScienceWatch.com
Interviews and Features
with:
The list of researchers is striking for the number of authors
who’ve returned from
last year’s compilation—or who’ve
reappeared following brief absences—as well as for
particular topics that remain highly active and highly cited.
One such topic is the reprogramming of fibroblast cells into a
pluripotent state resembling embryonic
stem cells, an endeavor embodied here by
Rudolf Jaenisch of the Whitehead Institute of MIT.
Jaenisch, who occupied the upper rungs of last year’s
report, tops the current list with 14 Hot Papers on the
investigation of reprogrammed cells in models of
Parkinson’s disease, sickle-cell
anemia, and other conditions.
Another hot topic from last year’s
roundup—
graphene—appears again, as discussed in the Hot
Papers of
Andre K. Geim, who returns from last year, along with his
frequent coauthor and University of Manchester colleague
Konstantin
Novoselov. The two were joined on several of these reports
by a new name, Mikhail Katsnelson of Radboud University of
Nijmegen, Netherlands. (Note: the order of names within each
tier is determined by average citations per Hot Paper.)
Mark J. Daly, of the Harvard Medical School, the Broad
Institute of MIT and Harvard, and Massachusetts General
Hospital, last seen in the 2007 report, finds his way back to
the list with 13 Hot Papers on genetic mapping and genome-wide
association studies. Several of these reports were coauthored
with Harvard/Broad colleagues David Altshuler and Paul I.W. de
Bakker, along with Goncalo Abecasis of the University of
Michigan; all three are making their first appearance in a
year-end roundup.
On the other hand,
Eric S. Lander, the Broad Institute’s founding
director, has been featured on numerous occasions, the last in
2004. He scores again here with 10 Hot Papers on general
genomic analysis as well as studies of lung cancer and
multiple
sclerosis.
Carlo M. Croce of Ohio State University, who last appeared
on 2008’s list, emerges again with 12 hot reports on
microRNA and its role in colon cancer, leukemia, and other
malignancies.
In the sphere of mathematics,
Ji-Huan
He of Donghua University makes a return appearance from
last year, with 10 Hot Papers on the variational iteration
method and other formulations.
Finally, this year marks the return of a fixture of these
roundups in recent years: immunologist
Shizuo Akira
(see also |
see also) of Osaka University, last seen on the list in
2008, who emerges with 9 Hot Papers on
toll-like
receptors and aspects of innate immunity.
Among 2009’s most-cited papers, the physical sciences
make a strong showing, notably in reports from the five-year
release of data from the Wilkinson Microwave Anisotropy
Probe, accounting for three of the top ten papers. Cosmic
rays and dark matter also figure among the
year’s hottest reports.
And by now it’s customary to remark on the strong showing
of the New England Journal of Medicine: 11 of the 44
featured papers.
Christopher King is the Editor of the Science
Watch® Newsletter, Thomson
Reuters.
E. Komatsu, et al., "Five-year
Wilkinson Microwave Anisotropy Probe
observations: Cosmological
interpretation,"Astrophys. J.
Suppl. Ser., 180(2): 330-76, February
2009.
659
2
J. Dunkley, et al., "Five-year
Wilkinson Microwave Anistropy Probe
observations: Likelihoods and parameters from
the WMAP data,"Astrophys. J. Suppl. Ser., 180(2):
306-29, February 2009.
274
3
O. Adriani, et al., "An
anomalous positron abundance in cosmic rays
with energies 1.5-100 GeV,"Nature, 458(7238): 607-9, 2 April
2009.
173
4
W. Duckworth, et al., "Glucose
control and vascular complications in veterans
with type 2 diabetes,"New Engl.
J. Med., 360(2): 129-39, 8 January 2009.
172
5
G. Hinshaw, et al., "Five-year
Wilkinson Microwave Anisotropy Probe
observations: Data processing, sky maps, and
basic results,"Astrophys. J.
Suppl. Ser., 180(2): 225-45, February
2009.
171
6
F.H. Schröder, et al.,
"Screening and prostate-cancer
mortality in a randomized European
study,"New Engl. J. Med.,
360(13): 1320-8, 26 March 2009.
148
7
Novel Swine-Origin Influenza A
(
H1N1) Virus Investigation Team (F.S.
Dawood, et al.), "Emergence of
a novel swine-origin influenza A (H1N1) virus
in humans,"New Engl. J.
Med., 360(25): 2605-15, 18 June 2009.
141
8
N. Arkani-Hamed, et al., "A
theory of dark matter,"Phys. Rev.
D, 79(1): No. 015014, January 2009.
137
9
G.L. Andriole, et al.,
"Mortality results from a randomized
prostate-cancer screening trial,"New Engl. J. Med., 360(13): 1310-9, 26
March 2009.
130
10
J.L. Mega, et al., "Cytochrome
P-450 polymorphisms and response to
clopidogrel,"New Engl. J.
Med., 360(4): 354-62, 22 January 2009.
120
11
S. Finfer, et al., "Intensive
versus conventional glucose control in
critically ill patients,"New
Engl. J. Med., 360(13): 1283-97, 26 March
2009.
109
12
O. Adriani, et al., "New
measurement of the antiproton-to-proton flux
ratio of up to 100GeV in the cosmic
radiation,"Phys. Rev. Lett.,
102(5): No. 051101, 6 February 2009.
108
13
K.S. Kim, et al., "Large-scale
pattern growth of graphene films for
stretchable transparent electrodes,"Nature, 457(7230): 706-10, 5 February
2009.
102
14
S.M. Lippman, et al., "Effect
of selenium and vitamin E on risk of prostate
cancer and other cancers: The Selenium and
Vitamin E Cancer Prevention Trial
(SELECT),"JAMA, 301(1):
39-51, 7 January 2009.
102
15
D.C. Elias, et al., "Control
of graphene’s properties by reversible
hydrogenation: Evidence for graphane,"Science, 323(5914): 610-3, 30 January
2009.
96
16
Z. Ahmed, et al., "Search for
weakly interacting massive particles with the
first five-tower data from the Cryogenic Dark
Matter Search at the Soudan Underground
Laboratory,"Phys. Rev.
Lett., 102(1): No. 011301, 9 January 2009.
95
17
M. Cirelli, "Model-independent
implications of the e(+/-), P
(over-bar) cosmic ray spectra on properties of
Dark Matter,"Nucl. Phys. B,
813(1-2): 1-21, 21 May 2009.
95
18
C. Fraser, et al., "Pandemic
potential of a strain of influenza A (H1N1):
Early findings,"Science,
324(5934): 1557-61, 19 June 2009.
93
19
C.J. Willer, et al., "Six new
loci associated with body mass index highlight
a neuronal influence on body weight
regulation,"Nature Genetics,
41(1): 25-34, January 2009.
91
20
A. Gustavsson, "Algebraic structures on
parallel M2 branes,"Nucl. Phys.
B, 811(1-2): 66-76, 11 April 2009.
89
21
T. Simon, et al., "Genetic
determinants of response to clopidogrel and
cardiovascular events,"New Engl.
J. Med., 360(4): 363-75, 22 January 2009.
85
22
M.R. Nolta, et al., "Five-year
Wilkinson Microwave Anisotropy Probe
observations: Angular power spectra,"Astrophys. J. Suppl. Ser., 180(2):
296-305, February 2009.
84
23
K. Woltjen, et al., "piggyBac
transposition reprograms fibroblasts to induced
pluripotent stem cells,"Nature, 458(7239): 766-70, 9 April
2009.
83
24
P.M. Ho, et al., "Risk of
adverse outcomes associated with concomitant
use of clopidogrel and proton pump inhibitors
following acute coronary syndrome,"JAMA, 301(9): 937-44, 4 March 2009.
81
25
A.A. Abdo, et al.,
"Measurement of the cosmic ray
e+ + e- spectrum from 20
GeV to 1 TeV with the Fermi Large Area
Telescope,"Phys. Rev. Lett.,
102(18): No. 181101, 8 May 2009.
80
26
V. Cvetkovic, et al.,
"Multiband magnetism and
superconductivity in Fe-based
compounds,"EPL, 85(3): No.
37002, February 2009.
80
27
P. Horava, "Quantum gravity at a
Lifshitz point,"Phys. Rev.
D, 79(8): No. 084008, April 2009.
77
28
P.W. Serruys, et al.,
"Percutaneous coronary intervention
versus coronary-artery bypass grafting for
severe coronary artery disease,"New Engl. J. Med., 360(10): 961-72, 5
March 2009.
77
29
M. Paez-Ribes, et al.,
"Antiangiogenic therapy elicits
malignant progression of tumors to increased
local invasion and distant
metastasis,"Cancer Cell,
15(3): 220-31, 3 March 2009.
77
30
S.H. Park, et al., "Bulk
heterojunction solar cells with internal
quantum efficiency approaching 100%,"Nature Photonics, 3(5): 297-302, May
2009.
70
31
G. Thorleifsson, et al.,
"Genome-wide association yields new
sequence variants at seven loci that associate
with measures of obesity,"Nature
Genetics, 41(1): 18-24, January 2009.
70
32
K. Kaji, et al., "Virus-free
induction of pluripotency and subsequent
excision of reprogramming factors,"Nature, 458(7239): 771-5, 9 April
2009.
69
33
P.L. Alireza, et al.,
"Superconductivity up to 29 K in
SrFe2As2 and
BaFe2As2 at high
pressures,"J. Physics- Condensed
Matter, 21(1): No. 012208, 7 January 2009.
69
34
A. Reina, et al., "Large area,
few-layer graphene films on arbitrary
substrates by chemical vapor
deposition,"Nano Letters,
9(1): 30-5, January 2009.
69
35
F. Soldner, et al.,
"Parkinson’s disease
patient-derived induced pluripotent stem cells
free of viral reprogramming factors,"Cell, 136(5): 964-77, 6 March 2009.
68
36
J.Y. Yu, et al., "Human
induced pluripotent stem cells free of vector
and transgene sequences,"Science, 324(5928): 797-801, 8 May
2009.
67
37
J.M.L. Ebos, et al.,
"Accelerated metastasis after
short-term treatment with a potent inhibitor of
tumor angiogenesis,"Cancer
Cell, 15(3): 232-9, 3 March 2009.
66
38
A. Garber, et al.,
"Liraglutide versus glimepiride
monotherapy for type 2 diabetes (LEAD-3 Mono):
a randomized, 52-week, phase III, double-blind,
parallel-treatment trial,"Lancet, 373(9662): 473-81, 7 February
2009.
65
39
R.J. Garten, et al.,
"Antigenic and genetic characteristics
of the swine-origin 2009 A(H1N1) influenza
viruses circulating in humans,"Science, 325(5937): 197-201, 10 July
2009.
64
40
F. Wang, et al., "Functional
renormalization-group study of the pairing
symmetry and pairing mechanism of the
FeAs-based high-temperature
superconductor,"Phys. Rev.
Lett., 102(4): No. 047005, 30 January
2009.
64
41
J. Tol, et al., "Chemotherapy,
bevacizumab, and cetuximab in metastatic
colorectal cancer,"New Engl. J.
Med., 360(6): 563-72, 5 February 2009.
63
42
T.E. Klein, et al.,
"Estimation of the warfarin dose with
clinical and pharmacogenetic data,"New Engl. J. Med., 360(8): 753-64, 19
February 2009.
62
43
J.P. Collet, et al.,
"Cytochrome P450 2C19 polymorphism in
young patients treated with clopidogrel after
myocardial infarction: a cohort
study,"Lancet, 373(9660):
309-17, 24 January 2009.
61
44
B.C. Fellstrom, et al.,
"Rosuvastatin and cardiovascular events
in patients undergoing hemodialysis,"New Engl. J. Med., 360(14): 1395-1407,
2 April 2009.
60
SOURCE:
ISI Web of
Knowledge® from
Clarivate (Citations recorded as of
late December 2009).
KEYWORDS: Hottest research of 2009, 2009’s most-cited
papers, Rudolf Jaenisch, Andre K. Geim, graphene, Wilkinson
Microwave Anisotropy Probe, WMAP, genomics.