The baseline time span for this database is 1998-December 31, 2008 (sixth
bimonthly period 2008). The resulting database contained 11,184 (10 years)
and 4,246 (2 years) papers. To construct the top 20 papers lists for the
past decade and the past two years, the papers were further narrowed down
by the title keywords "epigenet*." This adjustment resulted in the top 20
papers being selected from a pool of 2,510 (10 years) and 1,022 (2 years)
papers.
***Article 1
Total Cites: 1400
Article Title: The fundamental role of epigenetic events in cancer
Authors: Jones, PA, Baylin, SB
Journal: NATURE REVIEWS GENETICS
Volume: 3
Page: 415-428
Year: 2002
Addresses:
· UNIV SO CALIF, Keck Sch Med, Kenneth Norris Jr Comprehens Canc
Ctr, Dept Urol, Los Angeles, CA, USA
· UNIV SO CALIF, Keck Sch Med, Kenneth Norris Jr Comprehens Canc
Ctr, Dept Biochem, Los Angeles, CA, USA
· UNIV SO CALIF, Keck Sch Med, Kenneth Norris Jr Comprehens Canc
Ctr, Dept Mol Biol, Los Angeles, CA, USA
· JOHNS HOPKINS UNIV, Sidney Kimmel Comprehens Canc Ctr, Dept Oncol,
Baltimore, MD, USA
· JOHNS HOPKINS UNIV, Sidney Kimmel Comprehens Canc Ctr, Dept Med,
Baltimore, MD, USA
· USC, Keck Sch Med, Kenneth Norris Jr Comprehens Canc Ctr, Dept
Urol, Los Angeles, CA, USA
***Article 2
Total Cites: 1137
Article Title: Cancer epigenetics comes of age
Authors: Jones, PA, Laird, PW
Journal: NATURE GENETICS
Volume: 21
Page: 163-167
Year: 1999
Addresses:
· UNIV SO CALIF, Sch Med, Kenneth Norris Jr Comprehens Canc Ctr,
Dept Biochem & Mol Biol, Los Angeles, CA, USA
· UNIV SO CALIF, Sch Med, Kenneth Norris Jr Comprehens Canc Ctr,
Dept Surg, Los Angeles, CA, USA
· Univ So Calif, Sch Med, Kenneth Norris Jr Comprehens Canc Ctr,
Dept Biochem & Mol Biol, Los Angeles, CA, USA
***Article 3
Total Cites: 991
Article Title: DNA methylation patterns and epigenetic memory
Authors: Bird, A
Journal: GENE DEV
Volume: 16
Page: 39985
Year: 2002
Addresses:
· UNIV EDINBURGH, Wellcome Trust Ctr Cell Biol, Edinburgh,
Scotland
· Univ Edinburgh, Wellcome Trust Ctr Cell Biol, Edinburgh,
Scotland
***Article 4 Special
Topics Interview with Rudolf Jaenisch
Total Cites: 736
Article Title: Epigenetic regulation of gene expression: how the genome
integrates intrinsic and environmental signals
Authors:
Jaenisch,
R, Bird, A
Journal: NATURE GENETICS
Volume: 33
Page: 245-254
Year: 2003
Addresses:
· MIT, Whitehead Inst Biomed Res, Cambridge, MA, USA
· MIT, Dept Biol, Cambridge, MA, USA
· UNIV EDINBURGH, Wellcome Trust Ctr Cell Biol, Edinburgh,
Scotland
· MIT, Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA,
USA
***Article 5
Total Cites: 641
Article Title: DNA hypermethylation in tumorigenesis - epigenetics joins
genetics
Authors: Baylin, SB, Herman, JG
Journal: TRENDS IN GENETICS
Volume: 16
Page: 168-174
Year: 2000
Addresses:
· JOHNS HOPKINS UNIV, Baltimore, MD, USA
· Johns Hopkins Oncol Ctr, 1650 E Orleans St, Baltimore, MD,
USA
***Article 6
Total Cites: 597
Article Title: Role of histone H3 lysine 9 methylation in epigenetic
control of heterochromatin assembly
Authors: Nakayam, J, Rice, JC, Strahl, BD, Allis, CD, Grewal, SIS
Journal: SCIENCE
Volume: 292
Page: 110-113
Year: 2001
Addresses:
· COLD SPRING HARBOR LAB, Cold Spring Harbor, NY, USA
· UNIV VIRGINIA, Dept Biochem & Mol Genet, Charlottesville, VA,
USA
· Cold Spring Harbor Lab, POB 100, Cold Spring Harbor, NY, USA
***Article 7
Total Cites: 540
Article Title: Epigenetic reprogramming in mammalian development
Authors: Reik, W, Dean, W, Walter, J
Journal: SCIENCE
Volume: 293
Page: 1089-1093
Year: 2001
Addresses:
· BABRAHAM INST, Lab Dev Genet & Imprinting, Cambridge,
England
· UNIV SAARLAND, Fr Genet 8 2, Saarbrucken, Germany
· Babraham Inst, Lab Dev Genet & Imprinting, Cambridge,
England
***Article 8
Total Cites: 502
Article Title: Epigenetic programming by maternal behavior
Authors: Weaver, ICG, Cervoni, N, Champagne, FA, Dalessio, AC, Sharma, S,
Seckl, JR, Dymov, S, Szyf, M, Meaney, MJ
Journal: NATURE NEUROSCIENCE
Volume: 7
Page: 847-854
Year: 2004
Addresses:
· DOUGLAS HOSP, Res Ctr, Montreal, Canada
· MCGILL UNIV, Dept Pharmacol & Therapeut, Montreal,
Canada
· WESTERN GEN HOSP, Mol Med Ctr, Western Gen Hosp, Edinburgh,
Scotland
· MCGILL UNIV, McGill Program Study Behav Genes & Environm,
Montreal, Canada
· Douglas Hosp, Res Ctr, 6875 LaSalle Blvd, Montreal, Canada
***Article 9
Total Cites: 494
Article Title: Epigenetic inactivation of a RAS association domain family
protein from the lung tumour suppressor locus 3p21.3
Authors: Dammann, R, Li, C, Yoon, JH, Chin, PL, Bates, S, Pfeifer, GP
Journal: NATURE GENETICS
Volume: 25
Page: 315-319
Year: 2000
Addresses:
· CITY HOPE NATL MED CTR, Beckman Res Inst, Dept Biol, Duarte, CA,
USA
· City Hope Natl Med Ctr, Beckman Res Inst, Dept Biol, Duarte, CA,
USA
***Article 10
Total Cites: 483
Article Title: Chromatin modification and epigenetic reprogramming in
mammalian development
Authors: Li, E
Journal: NATURE REVIEWS GENETICS
Volume: 3
Page: 662-673
Year: 2002
Addresses:
· HARVARD UNIV, Sch Med, Massachusetts Gen Hosp, Cardiovasc Res
Ctr,Dept Med, Charlestown, MA, USA
· Harvard Univ, Sch Med, Massachusetts Gen Hosp, Cardiovasc Res
Ctr,Dept Med, Charlestown, MA, USA
***Article 11
Total Cites: 457
Article Title: Epigenetics in human disease and prospects for epigenetic
therapy
Authors: Egger, G, Liang, GN, Aparicio, A, Jones, PA
Journal: NATURE
Volume: 429
Page: 457-463
Year: 2004
Addresses:
· UNIV SO CALIF, Dept Biochem & Mol Biol, Los Angeles, CA,
USA
· UNIV SO CALIF, Keck Sch Med, USC Norris Comprehens Canc Ctr, Dept
Urol, Los Angeles, CA, USA
· Univ So Calif, Dept Biochem & Mol Biol, 1441 Eastlake Ave,Room
8302L, Los Angeles, CA, USA
***Article 13
Total Cites: 405
Article Title: Centromeres and kinetochores: From epigenetics to mitotic
checkpoint signaling
Authors: Cleveland, DW, Mao, YH, Sullivan, KF
Journal: CELL
Volume: 112
Page: 407-421
Year: 2003
Addresses:
· UNIV CALIF SAN DIEGO, Ludwig Inst Canc Res, La Jolla, CA,
USA
· UNIV CALIF SAN DIEGO, Dept Cellular & Mol Med, La Jolla, CA,
USA
· SCRIPPS RES INST, La Jolla, CA, USA
· Univ Calif San Diego, Ludwig Inst Canc Res, 9500 Gilman Dr, La
Jolla, CA, USA
***Article 14
Total Cites: 381
Article Title: Epigenetics: Regulation through repression
Authors: Wolffe, AP, Matzke, MA
Journal: SCIENCE
Volume: 286
Page: 481-486
Year: 1999
Addresses:
· NICHD, Mol Embryol Lab, NIH, Bethesda, MD, USA
· AUSTRIAN ACAD SCI, Inst Mol Biol, Salzburg, Austria
· NICHHD, Mol Embryol Lab, NIH, Bldg 18T,Room 106, Bethesda, MD,
USA
***Article 15
Total Cites: 380
Article Title: Epigenetic codes for heterochromatin formation and
silencing: Rounding up the usual suspects
Authors: Richards, EJ, Elgin, SCR
Journal: CELL
Volume: 108
Page: 489-500
Year: 2002
Addresses:
· WASHINGTON UNIV, Dept Biol, St Louis, MO, USA
· Washington Univ, Dept Biol, 1 Brookings Dr, St Louis, MO,
USA
***Article 16
Total Cites: 379
Article Title: Epigenetic inactivation of RASSF14 in lung and breast
cancers and malignant phenotype suppression
Authors: Burbee, DG, Forgacs, E, Zochbauer-muller, S, Shivakumar, L, Fong,
K, Gao, BN, Randle, D, Kondo, M, Virmani, A, Bader, S, Sekido, Y, Latif, F,
Milchgrub, S, Toyooka, S, Gazdar, AF, Lerman, MI, Zabarovsky, E, White, M,
Minna, JD
Journal: J NATL CANCER I
Volume: 93
Page: 691-699
Year: 2001
Addresses:
· UT SOUTHWESTERN MED CTR, SW Med Ctr Dallas, Hamon Ctr Therapeut
Oncol Res, Dallas, TX, USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr Dallas, Dept Cell Biol,
Dallas, TX, USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr Dallas, Dept Pathol, Dallas,
TX, USA
· PRINCE CHARLES HOSP, Dept Thorac Med, Brisbane, Australia
· UNIV BIRMINGHAM, Dept Reprod & Child Hlth, Birmingham,
England
· NCI, Immunobiol Lab, Frederick Canc Res & Dev Ctr, Frederick,
MD, USA
· KAROLINSKA INST, Stockholm, Sweden
· Univ Texas, SW Med Ctr Dallas, Hamon Ctr Therapeut Oncol Res, 6000
Harry Hines Blvd, Dallas, TX, USA
***Article 17
Total Cites: 340
Article Title: Epigenetic instability in ES cells and cloned mice
Authors: Humpherys, D, Eggan, K, Akutsu, H, Hochedlinger, K, Rideout, WM,
Biniszkiewicz, D, Yanagimachi, R,
Jaenisch,
R
Journal: SCIENCE
Volume: 293
Page: 95-97
Year: 2001
Addresses:
· MIT, Whitehead Inst Biomed Res, Cambridge, MA, USA
· MIT, Dept Biol, Cambridge, MA, USA
· UNIV HAWAII, John A Burns Sch Med, Dept Anat & Reprod Biol,
Honolulu, HI, USA
· MIT, Whitehead Inst Biomed Res, 9 Cambridge Ctr, Cambridge, MA,
USA
***Article 18
Total Cites: 339
Article Title: Heterochromatin and epigenetic control of gene
expression
Authors: Grewal, SIS, Moazed, D
Journal: SCIENCE
Volume: 301
Page: 798-802
Year: 2003
Addresses:
· NCI, Mol Cell Biol Lab, NIH, Bethesda, MD, USA
· HARVARD UNIV, Sch Med, Dept Cell Biol, Boston, MA, USA
***Article 19
Total Cites: 311
Article Title: Histone deacetylase inhibitors and the promise of epigenetic
(and more) treatments for cancer
Authors: Minucci, S, Pelicci, PG
Journal: NATURE REVIEWS CANCER
Volume: 6
Page: 38-51
Year: 2006
Addresses:
· EUROPEAN INST ONCOL, Dept Expt Oncol, Milan, Italy
· UNIV MILAN, Dept Biomolecular Sci & Biotechnol, Milan,
Italy
· UNIV MILAN, Dept Med, Milan, Italy
· European Inst Oncol, Dept Expt Oncol, Via Ripamanti 435, Milan,
Italy
***Article 20
Total Cites: 304
Article Title: Epigenetic regulation of cellular memory by the polycomb and
trithorax group proteins
Authors: Ringrose, L, Paro, R
Journal: ANNUAL REVIEW OF GENETICS
Volume: 38
Page: 413-443
Year: 2004
Addresses:
· UNIV HEIDELBERG, ZMBH, Heidelberg, Germany
· Univ Heidelberg, ZMBH, Heidelberg, Germany