The baseline time span for this database is 1998-April 30, 2008 (second
bimonthly period 2008). The resulting database contained 7,808 (10 years)
and 2,185 (2 years) papers.
***Article 1
Total Cites: 155
Article Title: A randomized, placebo-controlled trial of natalizumab for
relapsing multiple sclerosis
Authors: Polman, CH, Oconnor, PW, Havrdova, E, Hutchinson, M, Kappos, L,
Miller, DH, Phillips, JT, Lublin, FD, Giovannoni, G, Wajgt, A, Toal, M,
Lynn, F, Panzara, MA, Sandrock, AW, Affirm Investigators
Journal: NEW ENGL J MED
Volume: 354
Page: 899-910
Year: 2006
Addresses:
· VU Med Ctr, Amsterdam, Netherlands
· ST MICHAELS HOSP, Toronto, Canada
· GEN TEACHING HOSP, Prague, Czech Republic
· St Vincents Univ Hosp, Dublin, Ireland
· UNIV BASEL, Basel, Switzerland
· NEUROL INST, London, England
· Texas Neurol, Dallas, TX, USA
· CUNY MT SINAI SCH MED, New York, NY, USA
· Silesian Med Acad, Katowice, Poland
· Biogen Idec, Cambridge, MA, USA
· VU Med Ctr, POB 7057, Amsterdam, Netherlands
***Article 2
Total Cites: 99
Article Title: Medical progress: Multiple sclerosis - The plaque and its
pathogenesis
Authors: Frohman, EM, Racke, MK, Raine, CS
Journal: NEW ENGL J MED
Volume: 354
Page: 942-955
Year: 2006
Addresses:
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dept Neurol, Dallas, TX,
USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dept Ophthalmol, Dallas, TX,
USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Ctr Immunol, Dallas, TX,
USA
· YESHIVA UNIV, Div Neuropathol, Dept Pathol & Neurol, Bronx,
NY, USA
· Univ Texas, SW Med Ctr, Dept Neurol, 5323 Harry Hines Blvd,
Dallas, TX, USA
***Article 3
Total Cites: 97
Article Title: Natalizumab plus interferon beta-1a for relapsing multiple
sclerosis
Authors: Rudick, RA, Stuart, WH, Calabresi, PA, Confavreux, C, Galetta, SL,
Radue, EW, Lublin, FD, Weinstock-guttman, B, Wynn, DR, Lynn, F, Panzara,
MA, Sandrock, AW, Sentinel Investigators
Journal: NEW ENGL J MED
Volume: 354
Page: 911-923
Year: 2006
Addresses:
· CLEVELAND CLIN FDN, Mellen Ctr Multiple Sclerosis Treatment &
Res, Cleveland, OH, USA
· MS Ctr Atlanta, Atlanta, GA, USA
· Johns Hopkins Multiple Sclerosis Ctr, Baltimore, MD, USA
· HOP NEUROL, Lyon, France
· UNIV PENN, Sch Med, Philadelphia, PA, USA
· UNIV BASEL, Basel, Switzerland
· CUNY MT SINAI SCH MED, New York, NY, USA
· SUNY BUFFALO, Buffalo, NY, USA
· Multiple Sclerosis Ctr, Northbrook, IL, USA
· Biogen Idec, Cambridge, MA, USA
· Cleveland Clin Fdn, Mellen Ctr Multiple Sclerosis Treatment &
Res, 9500 Euclid Ave, Cleveland, OH, USA
***Article 4
Total Cites: 73
Article Title: Oral fingolimod (FTY720) for relapsing multiple
sclerosis
Authors: Kappos, L, Antel, J, Comi, G, Montalban, X, Oconnor, P, Polman,
CH, Haas, T, Korn, AA, Karlsson, G, Radue, EW, Fty720 D2201 Study Grp
Journal: NEW ENGL J MED
Volume: 355
Page: 1124-1140
Year: 2006
Addresses:
· UNIV HOSP, Dept Neurol, Basel, Switzerland
· UNIV HOSP, Dept Res, Basel, Switzerland
· MCGILL UNIV, Montreal Neurol Inst, Ctr Univ Sante McGill,
Montreal, Canada
· Univ Vita & Salute, Hosp San Raffaele, Neurol Clin, Milan,
Italy
· HOSP VALLE DE HEBRON, Neuroimmunol Unit, Barcelona, Spain
· ST MICHAELS HOSP, Div Neurol, Toronto, Canada
· FREE UNIV AMSTERDAM, Med Ctr, Dept Neurol, Amsterdam,
Netherlands
· Novartis Pharma AG, Biostat & Stat Reporting, Basel,
Switzerland
· Novartis Pharma AG, Clin Dev & Med Affairs, Basel,
Switzerland
· Novartis Pharma AG, Clin Dev & Med Affairs, E Hanover, NJ,
USA
· UNIV HOSP, Neuroradiol & MS MRI Evaluat Ctr, Basel,
Switzerland
· Univ Hosp, Dept Neurol, Petersgraben 4, Basel, Switzerland
***Article 5
Total Cites: 67
Article Title: Understanding pathogenesis and therapy of multiple sclerosis
via animal models: 70 years of merits and culprits in experimental
autoimmune encephalomyelitis research
Authors: Gold, R, Linington, C, Lassmann, H
Journal: BRAIN
Volume: 129
Page: 1953-1971
Year: 2006
Addresses:
· UNIV GOETTINGEN, Inst Multiple Sclerosis Res, Gottingen,
Germany
· UNIV ABERDEEN, Inst Med Sci, Aberdeen, Scotland
· MED UNIV VIENNA, Ctr Brain Res, Vienna, Austria
· Inst Multiple Sclerosis Res, Dept Expt & Clin Neuroimmunol,
Waldweg 33, Gottingen, Germany
***Article 6
Total Cites: 52
Article Title: Mitochondrial dysfunction as a cause of axonal degeneration
in multiple sclerosis patients
Authors: Dutta, R, Mcdonough, J, Yin, XG, Peterson, J, Chang, A, Torres, T,
Gudz, T, Macklin, EB, Lewis, DA, Fox, RJ, Rudick, R, Mirnics, K, Trapp,
BD
Journal: ANNALS OF NEUROLOGY
Volume: 59
Page: 478-489
Year: 2006
Addresses:
· CLEVELAND CLIN FDN, Dept Neurosci NC30, Lerner Res Inst,
Cleveland, OH, USA
· CLEVELAND CLIN FDN, Mellen Ctr Multiple Sclerosis Treatment &
Res, Cleveland, OH, USA
· UNIV PITTSBURGH, Sch Med, Dept Psychiat, Pittsburgh, PA, USA
· Cleveland Clin Fdn, Dept Neurosci NC30, Lerner Res Inst, 9500
Euclid Ave, Cleveland, OH, USA
***Article 7
Total Cites: 41
Article Title: Innate immunity mediated by TLR9 modulates pathogenicity in
an animal model of multiple sclerosis
Authors: Prinz, M, Garbe, F, Schmidt, H, Mildner, A, Gutcher, I, Wolter, K,
Piesche, M, Schroers, R, Weiss, E, Kirschning, CJ, Rochford, CDP, Bruck, W,
Becher, B
Journal: JOURNAL OF CLINICAL INVESTIGATION
Volume: 116
Page: 456-464
Year: 2006
Addresses:
· UNIV GOTTINGEN, Inst Neuropathol, Gottingen, Germany
· UNIV ZURICH, Univ Spital, Dept Neurol, Neuroimmunol Unit, Zurich,
Switzerland
· UNIV GOTTINGEN, Dept Hematol & Oncol, Gottingen, Germany
· UNIV GOTTINGEN, Dept Radiat Oncol, Gottingen, Germany
· TECH UNIV MUNICH, Inst Med Microbiol Immunol & Hyg, Munich,
Germany
· European Neurosci Inst, Neuroimmunol Unit, Gottingen,
Germany
· Univ Gottingen, Inst Neuropathol, Robert Koch Str 40, Gottingen,
Germany
***Article 8
Total Cites: 40
Article Title: The window of therapeutic opportunity in multiple
sclerosis
Authors: Coles, AJ, Cox, A, Le Page, E, Jones, J, Trip, SA, Deans, J,
Seaman, S, Miller, DH, Hale, G, Waldmann, H, Compston, DA
Journal: JOURNAL OF NEUROLOGY
Volume: 253
Page: 98-108
Year: 2006
Addresses:
· ADDENBROOKES HOSP, Dept Clin Neurosci, Cambridge, England
· Univ Coll, Inst Neurol, London, England
· MRC, Biostat Unit, Cambridge, England
· UNIV OXFORD, Sir William Dunn Sch Pathol, Oxford, England
· Addenbrookes Hosp, Dept Clin Neurosci, Box 165, Cambridge,
England
***Article 9
Total Cites: 39
Article Title: How to successfully apply animal studies in experimental
allergic encephalomyelitis to research on multiple sclerosis
Authors: Steinman, L, Zamvil, SS
Journal: ANNALS OF NEUROLOGY
Volume: 60
Page: 39803
Year: 2006
Addresses:
· STANFORD UNIV, Beckman Ctr Mol Med, Dept Neurol & Neurol Sci,
Stanford, CA, USA
· UNIV CALIF SAN FRANCISCO, Dept Neurol, San Francisco, CA,
USA
· Stanford Univ, Beckman Ctr Mol Med, Dept Neurol & Neurol Sci,
Stanford, CA, USA
***Article 10
Total Cites: 38
Article Title: Remyelination is extensive in a subset of multiple sclerosis
patients
Authors: Patrikios, P, Stadelmann, C, Kutzelnigg, A, Rauschka, H,
Schmidbauer, M, Laursen, H, Sorensen, PS, Bruck, W, Lucchinetti, C,
Lassmann, H
Journal: BRAIN
Volume: 129
Page: 3165-3172
Year: 2006
Addresses:
· MED UNIV VIENNA, Ctr Brain Res, Vienna, Austria
· Municipal Hosp Lainz, Dept Neurol, Vienna, Austria
· UNIV GOETTINGEN, Dept Neuropathol, Gottingen, Germany
· UNIV COPENHAGEN, Rigshosp, Neuropathol Lab, Copenhagen,
Denmark
· UNIV COPENHAGEN, Dept Neurol, Copenhagen, Denmark
· MAYO CLIN & MAYO FDN, Dept Neurol, Rochester, MN, USA
· Med Univ Vienna, Ctr Brain Res, Spitalgasse 4, Vienna,
Austria
***Article 11
Total Cites: 37
Article Title: Risk alleles for multiple sclerosis identified by a
genomewide study
Authors: Hafler, DA, Compston, A, Sawcer, S, Lander, ES, Daly, MJ, De
Jager, PL, de Bakker, PIW, Gabriel, SB, Mirel, DB, Ivinson, AJ,
Pericak-vance, MA, Gregory, SG, Rioux, JD, Mccauley, JL, Haines, JL,
Barcellos, LF, Cree, B, Oksenberg, JR, Hauser, SL, Int Multiple Sclerosis
Genetics Co
Journal: NEW ENGL J MED
Volume: 357
Page: 851-862
Year: 2007
Addresses:
· BRIGHAM & WOMENS HOSP, Dept Neurol, Ctr Neurol Dis, Div Mol
Immunol, Boston, MA, USA
· HARVARD UNIV, Sch Med, Broad Inst, Boston, MA, USA
· MIT, Cambridge, MA, USA
· UNIV CAMBRIDGE, Addenbrookes Hosp, Sch Clin Med, Dept Clin
Neurosci, Cambridge, England
· HARVARD UNIV, Massachusetts Gen Hosp, Sch Med, Boston, MA,
USA
· Harvard Partners ctr Genet & Genom, Boston, MA, USA
· HARVARD UNIV, Sch Med, Harvard Ctr Neurodgenerat & Repair,
Boston, MA, USA
· DUKE UNIV, Med Ctr, Durham, NC, USA
· UNIV MIAMI, Sch Med, Miami, FL, USA
· UNIV MONTREAL, Montreal Heart Inst, Montreal, Canada
· VANDERBILT UNIV, Med Ctr, Ctr Human Genet Res, Nashville, TN,
USA
· UNIV CALIF BERKELEY, Berkeley, CA, USA
· UNIV CALIF SAN FRANCISCO, San Francisco, CA, USA
· Brigham & Womens Hosp, Dept Neurol, Ctr Neurol Dis, Div Mol
Immunol, Boston, MA, USA
***Article 12
Total Cites: 35
Article Title: Immune surveillance in multiple sclerosis patients treated
with natalizumab
Authors: Stuve, O, Marra, CM, Jerome, KR, Cook, L, Cravens, PD, Cepok, S,
Frohman, EM, Phillips, JT, Arendt, G, Hemmer, B, Monson, NL, Racke,
MK
Journal: ANNALS OF NEUROLOGY
Volume: 59
Page: 743-747
Year: 2006
Addresses:
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dept Neurol, Dallas, TX,
USA
· VA N Texas Hlth Care Syst, Med Serv, Neurol Sect, Dallas, TX,
USA
· UNIV DUSSELDORF, Dept Neurol, Dusseldorf, Germany
· UNIV WASHINGTON, Dept Neurol, Seattle, WA, USA
· UNIV WASHINGTON, Dept Lab Med, Seattle, WA, USA
· FRED HUTCHINSON CANC RES CTR, Seattle, WA, USA
· Multiple Sclerosis Ctr Texas Neurol, Dallas, TX, USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Ctr Immunol, Dallas, TX,
USA
· Univ Texas, SW Med Ctr, Dept Neurol, 5323 Harry Hines Blvd,
Dallas, TX, USA
***Article 13
Total Cites: 33
Article Title: Natural history of multiple sclerosis: a unifying
concept
Authors: Confavreux, C, Vukusic, S
Journal: BRAIN
Volume: 129
Page: 606-616
Year: 2006
Addresses:
· HOP NEUROL & NEUROCHIRURG P WERTHEIMER, Serv Neurol A, EDMUS
Coordinating Ctr, Lyon, France
· HOP NEUROL, INSERM, U433, Lyon, France
· Hop Neurol & Neurochirurg P Wertheimer, Serv Neurol A, EDMUS
Coordinating Ctr, 59 Blvd Pinel, Lyon, France
***Article 14
Total Cites: 33
Article Title: Relation of visual function to retinal nerve fiber layer
thickness in multiple sclerosis
Authors: Fisher, JB, Jacobs, DA, Markowitz, CE, Galetta, SL, Volpe, NJ,
Nano-schiavi, ML, Baier, ML, Frohman, EM, Winslow, H, Frohman, TC,
Calabresi, PA, Maguire, MG, Cutter, GR, Balcer, LJ
Journal: OPHTHALMOLOGY
Volume: 113
Page: 324-332
Year: 2006
Addresses:
· UNIV PENN, Sch Med, Dept Neurol, Div Neuroophthalmol,Scheie Eye
Inst, Philadelphia, PA, USA
· UNIV PENN, Sch Med, Dept Ophthalmol, Scheie Eye Inst,
Philadelphia, PA, USA
· UNIV PENN, Sch Med, Dept Biostat, Scheie Eye Inst, Philadelphia,
PA, USA
· UNIV ALABAMA, Dept Biostat, Birmingham, AL, USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dept Neurol, Dallas, TX,
USA
· JOHNS HOPKINS UNIV, Sch Med, Dept Neurol, Baltimore, MD, USA
· 3 E Gates Bldg,3400 Spruce St, Philadelphia, PA, USA
***Article 15
Total Cites: 30
Article Title: The neurobiology of multiple sclerosis: Genes, inflammation,
and neurodegeneration
Authors: Hauser, SL, Oksenberg, JR
Journal: NEURON
Volume: 52
Page: 61-76
Year: 2006
Addresses:
· UNIV CALIF SAN FRANCISCO, Dept Neurol, Sch Med, San Francisco, CA,
USA
· Univ Calif San Francisco, Dept Neurol, Sch Med, San Francisco, CA,
USA
***Article 16
Total Cites: 30
Article Title: Chemokines in multiple sclerosis: CXCL12 and CXCL13
up-regulation is differentially linked to CNS immune cell recruitment
Authors: Krumbholz, M, Theil, D, Cepok, S, Hemmer, B, Kivisakk, P,
Ransohoff, RM, Hofbauer, M, Farina, C, Derfuss, T, Hartle, C, Newcombe, J,
Hohlfeld, R, Meinl, E
Journal: BRAIN
Volume: 129
Page: 200-211
Year: 2006
Addresses:
· Max Planck Society, Dept Neuroimmunol, Martinsried, Germany
· UNIV MUNICH, Inst Clin Neuroimmunol, Munich, Germany
· UNIV MUNICH, Dept Neurol, Munich, Germany
· UNIV DUSSELDORF, Dept Neurol, Dusseldorf, Germany
· CLEVELAND CLIN FDN, Lerner Res Inst, Dept Neurosci, Cleveland, OH,
USA
· UCL, Inst Neurol, London, England
· Max Planck Inst Neurobiol, Dept Neuroimmunol, Klopferspitz 18,
Martinsried, Germany
***Article 17
Total Cites: 29
Article Title: IL-23 is increased in dendritic cells in multiple sclerosis
and down-regulation of IL-23 by antisense oligos increases dendritic cell
IL-10 production
Authors: Vaknin-dembinsky, A, Balashov, K, Weiner, HL
Journal: JOURNAL OF IMMUNOLOGY
Volume: 176
Page: 7768-7774
Year: 2006
Addresses:
· BRIGHAM & WOMENS HOSP, Ctr Neurol Dis, Boston, MA, USA
· Brigham & Womens Hosp, Ctr Neurol Dis, Boston, MA, USA
***Article 18
Total Cites: 28
Article Title: A prospective open-label study of glatiramer acetate: over a
decade of continuous use in multiple sclerosis patients
Authors: Ford, CC, Johnson, KP, Lisak, RP, Panitch, HS, Shifroni, G,
Wolinsky, JS, Copaxone Study Grp
Journal: MULTIPLE SCLEROSIS
Volume: 12
Page: 309-320
Year: 2006
Addresses:
· Maryland Ctr Multiple Sclerosis, Baltimore, MD, USA
· MIND Imaging Ctr, Albuquerque, NM, USA
· WAYNE STATE UNIV, Detroit, MI, USA
· UNIV VERMONT, Burlington, VT, USA
· TEVA PHARMACEUT IND LTD, Petah Tiqwa, Israel
· UNIV TEXAS HLTH SCI CTR HOUSTON, Hlth Sci Ctr, Houston, TX,
USA
· Maryland Ctr Multiple Sclerosis, 11 S Paca St,4th Floor,
Baltimore, MD, USA
***Article 19
Total Cites: 28
Article Title: IM interferon beta-1a delays definite multiple sclerosis 5
years after a first demyelinating event
Authors: Kinkel, RP, Kollman, C, Oconnor, P, Murray, TJ, Simon, J, Arnold,
D, Bakshi, R, Weinstock-gutman, B, Brod, S, Cooper, J, Duquette, P,
Eggenberger, E, Felton, W, Fox, R, Freedman, M, Galetta, S, Goodman, A,
Guarnaccia, J, Hashimoto, S, Horowitz, S, Javerbaum, J, Kasper, L, Kaufman,
M, Kerson, L, Mass, M, Rammohan, K, Reiss, M, Rolak, L, Rose, J, Scott, T,
Selhorst, J, Shin, R, Smith, C, Stuart, W, Thurston, S, Wall, M, Champions
Study Grp
Journal: NEUROLOGY
Volume: 66
Page: 678-684
Year: 2006
Addresses:
· HARVARD UNIV, Beth Israel Deaconess Med Ctr, Multiple Sclerosis
Ctr, Sch Med, Boston, MA, USA
· Harvard Univ, Beth Israel Deaconess Med Ctr, Multiple Sclerosis
Ctr, Sch Med, Boston, MA, USA
***Article 20
Total Cites: 27
Article Title: Epstein-Barr virus and multiple sclerosis - Evidence of
association from a prospective study with long-term follow-up
Authors: Delorenze, GN, Munger, KL, Lennette, ET, Orentreich, N, Vogelman,
JH, Ascherio, A
Journal: ARCH NEUROL-CHICAGO
Volume: 63
Page: 839-844
Year: 2006
Addresses:
· KAISER PERMANENTE, Div Res, Oakland, CA, USA
· HARVARD UNIV, Sch Publ Hlth, Dept Nutr, Cambridge, MA, USA
· HARVARD UNIV, Sch Publ Hlth, Dept Epidemiol, Cambridge, MA,
USA
· BRIGHAM & WOMENS HOSP, Channing Lab, Boston, MA, USA
· HARVARD UNIV, Sch Med, Boston, MA, USA
· VIROLAB INC, Berkeley, CA, USA
· ORENTREICH FDN ADVANCEMENT SCI INC, New York, NY, USA
· 665 Huntington Ave, Boston, MA, USA