The baseline time span for this database is 1998-June 30, 2008 (third
bimonthly period 2008). To construct the top 20 papers lists for the past
decade and the past two years, the papers were further narrowed down by the
title keywords "rheumatoid arthritis." This adjustment resulted in the top
20 papers being selected from a pool of 8,898 (10 years) and 2,504 (2
years) papers.
***Article 1
Total Cites: 236
Article Title: Anti-TNF antibody therapy in rheumatoid arthritis and the
risk of serious infections and malignancies - Systematic review and
meta-analysis of rare harmful effects in randomized controlled trials
Authors: Bongartz, T, Sutton, AJ, Sweeting, MJ, Buchan, I, Matteson, EL,
Montori, V
Journal: JAMA-J AM MED ASSOC
Volume: 295
Page: 2275-2285
Year: 2006
Addresses:
· MAYO CLIN & MAYO FDN, Coll Med, Div Rheumatol, Rochester, MN,
USA
· MAYO CLIN & MAYO FDN, Coll Med, Dept Internal Med, Rochester,
MN, USA
· UNIV LEICESTER, Dept Hlth Sci, Leicester, England
· INST PUBL HLTH, MRC, Biostat Unit, Cambridge, England
· UNIV MANCHESTER, NW Inst Biohlth Informat, Manchester,
England
· MAYO CLIN & MAYO FDN, Coll Med, Knowledge & Encounter Res
Unit, Rochester, MN, USA
· MAYO CLIN & MAYO FDN, Coll Med, Dept Med, Rochester, MN,
USA
· Mayo Clin, Coll Med, Div Rheumatol, 200 1st St SW, Rochester, MN,
USA
***Article 2
Total Cites: 144
Article Title: The PREMIER study - A multicenter, randomized, double-blind
clinical trial of combination therapy with adalimumab plus methotrexate
versus methotrexate alone or adalimumab alone in patients with early,
aggressive rheumatoid arthritis who had not had previ
Authors: Breedveld, FC, Weisman, MH, Kavanaugh, AF, Cohen, SB, Pavelka, K,
van Vollenhoven, R, Sharp, J, Perez, JL, Spencer-green, GT, Premier
Investigatiors
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 26-37
Year: 2006
Addresses:
· LEIDEN UNIV, Med Ctr, Dept Rheumatol, Leiden, Netherlands
· CEDARS SINAI MED CTR, Los Angeles, CA, USA
· UNIV CALIF SAN DIEGO, Ctr Innovat Therapy, La Jolla, CA, USA
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dallas, TX, USA
· INST RHEUMATOL, Prague, Czech Republic
· KAROLINSKA INST, Stockholm, Sweden
· UNIV WASHINGTON, Seattle, WA, USA
· ABBOTT LABS, Parsippany, NJ, USA
· Leiden Univ, Med Ctr, Dept Rheumatol, Albinusdreef 2,C4-R POB
9600, Leiden, Netherlands
***Article 3
Total Cites: 91
Article Title: A new model for an etiology of rheumatoid arthritis
Authors: Klareskog, L, Stolt, P, Lundberg, K, Kallberg, H, Bengtsson, C,
Grunewald, J, Ronnelid, J, Harris, HE, Ulfgren, AK, Rantapaa-dahlqvist, S,
Eklund, A, Padyukov, L, Alfredsson, L, Epidemiological Investigation
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 38-46
Year: 2006
Addresses:
· KAROLINSKA UNIV HOSP, Karolinska Inst, Rheumatol Unit, Dept Med,
Stockholm, Sweden
· KAROLINSKA INST, Stockholm, Sweden
· VASTERAS CTY HOSP, Vasteras, Sweden
· UNIV UPPSALA, Akad Sjukhuset, Uppsala, Sweden
· NORRLAND UNIV HOSP, Umea, Sweden
· Karolinska Univ Hosp, Karolinska Inst, Rheumatol Unit, Dept Med,
Stockholm, Sweden
***Article 4
Total Cites: 88
Article Title: The efficacy and safety of rituximab in patients with active
rheumatoid arthritis despite methotrexate treatment - Results of a phase
IIb randomized, double-blind, placebo-controlled, dose-ranging trial
Authors: Emery, P, Fleischmann, R, Filipowicz-sosnowska, A, Schechtman, J,
Szczepanski, L, Kavanaugh, A, Racewicz, AJ, Van Vollenhoven, RF, Li, NF,
Agarwal, S, Hessey, EW, Shaw, TM, Dancer Study Grp
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 1390-1400
Year: 2006
Addresses:
· CHAPEL ALLERTON HOSP, Acad Unit Musculoskeletal Dis, Leeds,
England
· UT SOUTHWESTERN MED CTR, SW Med Ctr, Dallas, TX, USA
· INST RHEUMATOL, Warsaw, Poland
· Sun Valley Arthritis Ctr, Glendale, AZ, USA
· UNIV CALIF SAN DIEGO, La Jolla, CA, USA
· Bialystok Reg Hosp, Bialystok, Poland
· KAROLINSKA UNIV HOSP, Stockholm, Sweden
· GENENTECH INC, San Francisco, CA, USA
· ROCHE PROD LTD, Welwyn Garden City, England
· Chapel Allerton Hosp, Acad Unit Musculoskeletal Dis, Chapeltown
Rd, Leeds, England
***Article 5
Total Cites: 79
Article Title: Rituximab for rheumatoid arthritis refractory to anti-tumor
necrosis factor therapy - Results of a multicenter, randomized,
double-blind, placebo-controlled, phase III trial evaluating primary
efficacy and safety at twenty-four weeks
Authors: Cohen, SB, Emery, P, Greenwald, MW, Dougados, M, Furie, RA,
Genovese, MC, Keystone, EC, Loveless, JE, Burmester, GR, Cravets, MW,
Hessey, EW, Shaw, T, Totoritis, MC, Reflex Trial Grp
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 2793-2806
Year: 2006
Addresses:
· Radiant Res, Dallas, TX, USA
· GEN INFIRM, Leeds, England
· Desert Med Advances, Palm Desert, CA, USA
· UNIV PARIS 5, Paris, France
· N Shore Long Isl Jewish Hlth Syst, Lake Success, NY, USA
· STANFORD UNIV, Med Ctr, Stanford, CA, USA
· UNIV TORONTO, Toronto, Canada
· Intermt Orthoped, Boise, ID, USA
· UNIV HOSP, Charite, Berlin, Germany
· Biogen Idec, San Diego, CA, USA
· ROCHE PROD LTD, Welwyn Garden City, England
· Radiant Res, 5939 Harry Hines Blvd,Suite 441, Dallas, TX,
USA
***Article 6
Total Cites: 67
Article Title: Association of chronic inflammation, not its treatment, with
increased lymphoma risk in rheumatoid arthritis
Authors: Baecklund, E, Iliadou, A, Askling, J, Ekborn, A, Backlin, C,
Granath, F, Catrina, AT, Rosenquist, R, Feltelius, N, Sundstrom, C,
Klareskog, L
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 692-701
Year: 2006
Addresses:
· Akademiska Hosp, Dept Rheumatol, Uppsala, Sweden
· KAROLINSKA INST, Karolinska Univ Hosp, Stockholm, Sweden
· HARVARD UNIV, Sch Publ Hlth, Boston, MA, USA
· UNIV UPPSALA, Uppsala, Sweden
· SWEDISH MED PROD AGCY, Uppsala, Sweden
***Article 7
Total Cites: 67
Article Title: B-cell targeting in rheumatoid arthritis and other
autoimmune diseases
Authors: Edwards, JCW, Cambridge, G
Journal: NATURE REVIEWS IMMUNOLOGY
Volume: 6
Page: 394-403
Year: 2006
Addresses:
· UCL, Dept Med, London, England
· UCL, Dept Med, 46 Cleveland St, London, England
***Article 8
Total Cites: 66
Article Title: Effects of abatacept in patients with methotrexate-resistant
active rheumatoid arthritis - A randomized trial
Authors: Kremer, JM, Genant, HK, Moreland, LW, Russell, AS, Emery, P,
Abud-mendoza, C, Szechinski, J, Li, T, Ge, ZY, Becker, JC, Westhovens,
R
Journal: ANNALS OF INTERNAL MEDICINE
Volume: 144
Page: 865-876
Year: 2006
Addresses:
· CTR RHEUMATOL, Albany, NY, USA
· UNIV CALIF SAN FRANCISCO, San Francisco, CA, USA
· Synarc Inc, San Francisco, CA, USA
· UNIV ALABAMA, Med Sch Birmingham, Birmingham, AL, USA
· UNIV ALBERTA, Edmonton, Canada
· UNIV LEEDS, Leeds, England
· CENT HOSP, San Luis Potosi, Mexico
· UNIV MED SCI, Wroclaw, Poland
· BRISTOL MYERS SQUIBB CO, Princeton, NJ, USA
· CATHOLIC UNIV LEUVEN, Louvain, Belgium
· Ctr Rheumatol, 1367 Washington Ave,Suite 1, Albany, NY, USA
***Article 9
Total Cites: 63
Article Title: Rates of serious infection, including site-specific and
bacterial intracellular infection, in rheumatoid arthritis patients
receiving anti-tumor necrosis factor therapy - Results from the British
Society for Rheumatology Biologics Register
Authors: Dixon, WG, Watson, K, Lunt, M, Hyrich, KL, Silman, AJ, Symmons,
DPM, British Soc Rheumatology Biologics
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 2368-2376
Year: 2006
Addresses:
· UNIV MANCHESTER, Div Epidemiol & Hlth Sci, Epidemiol Unit,
Manchester, England
· Univ Manchester, Div Epidemiol & Hlth Sci, Epidemiol Unit,
Stopford Bldg,Oxford Rd, Manchester, England
***Article 10
Total Cites: 62
Article Title: Tumor necrosis factor inhibitors for rheumatoid
arthritis
Authors: Scott, DL, Kingsley, GH
Journal: NEW ENGL J MED
Volume: 355
Page: 704-712
Year: 2006
Addresses:
· KINGS COLL LONDON, Kings Coll London Sch Med, Dept Rheumatol,
London, England
· Kings Coll London Hosp, Dept Rheumatol, London, England
· Univ Hosp Lewisham, Dept Rheumatol, London, England
· Kings Coll London, Kings Coll London Sch Med, Dept Rheumatol,
London, England
***Article 11
Total Cites: 56
Article Title: Safety analyses of adalimumab (HUMIRA) in global clinical
trials and US postmarketing surveillance of patients with rheumatoid
arthritis
Authors: Schiff, MH, Burmester, GR, Kent, JD, Pangan, AL, Kupper, H,
Fitzpatrick, SB, Donovan, C
Journal: ANNALS OF THE RHEUMATIC DISEASES
Volume: 65
Page: 889-894
Year: 2006
Addresses:
· DENVER ARTHRIT CLIN PC, Denver, CO, USA
· HUMBOLDT UNIV BERLIN, Charite, Dept Rheumatol, Berlin,
Germany
· ABBOTT LABS, Abbott Pk, IL, USA
· Abbott GmbH & Co KG, Immunosci Europe, Ludwigshafen,
Germany
· ABBOTT LABS, PostmktSafety Evaluat, Abbott Pk, IL, USA
· ABBOTT LABS, Parsippany, NJ, USA
· Denver Arthrit Clin PC, 200 Spruce St,Suite 100, Denver, CO,
USA
***Article 12
Total Cites: 51
Article Title: Reconstitution of peripheral blood B cells after depletion
with rituximab in patients with rheumatoid arthritis
Authors: Leandro, MJ, Cambridge, G, Ehrenstein, MR, Edwards, JCW
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 613-620
Year: 2006
Addresses:
· UCL, Ctr Rheumatol, London, England
· UCL, Ctr Rheumatol, Windeyer Bldg,Room 317,46 Cleveland St,
London, England
***Article 13
Total Cites: 51
Article Title: Double-blind randomized controlled clinical trial of the
interleukin-6 receptor antagonist, tocilizumab, in European patients with
rheumatoid arthritis who had an incomplete response to methotrexate
Authors: Maini, RN, Taylor, PC, Szechinski, J, Pavelka, K, Broll, J,
Balint, G, Emery, P, Raemen, F, Petersen, J, Smolen, J, Thomson, D,
Kishimoto, T, Charisma Study Grp
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 2817-2829
Year: 2006
Addresses:
· UNIV LONDON IMPERIAL COLL SCI TECHNOL & MED, Kennedy Inst
Rheumatol, London, England
· Univ Sch Wroclaw, Wroclaw, Poland
· INST RHEUMATOL, Prague, Czech Republic
· LUDWIG BOLTZMANN INST RHEUMATOL & BALNEOL, Vienna,
Austria
· NATL INST RHEUMATISM & PHYSIOTHERAPY, Budapest, Hungary
· UNIV LEEDS, Leeds, England
· AZ Jan Palfijn Hosp, Antwerp, Belgium
· STATE UNIV HOSP, Finsen Ctr, Copenhagen, Denmark
· MED UNIV VIENNA, Vienna, Austria
· LAINZ HOSP, Vienna, Austria
· Chugai Pharma Europe, London, England
· OSAKA UNIV, Osaka, Japan
· Univ London Imperial Coll Sci & Technol, Kennedy Inst
Rheumatol, London, England
***Article 14
Total Cites: 49
Article Title: Diagnostic and predictive value of anti-cyclic citrullinated
protein antibodies in rheumatoid arthritis: a systematic literature
review
Authors: Avouac, J, Gossec, L, Dougados, M
Journal: ANNALS OF THE RHEUMATIC DISEASES
Volume: 65
Page: 845-851
Year: 2006
Addresses:
· HOP COCHIN, APHP, Rheumatol B Det, Paris, France
· UNIV PARIS 5, Fac Med, Paris, France
· Hop Cochin, APHP, Rheumatol B Det, 27 Rue Faubourg St Jacques,
Paris, France
***Article 15
Total Cites: 47
Article Title: Comparison of etanercept and methotrexate, alone and
combined, in the treatment of rheumatoid arthritis - Two-year clinical and
radiographic results from the TEMPO study, a double-blind, randomized
trial
Authors: van der Heijde, D, Klareskog, L, Rodriguez-valverde, V, Codreanu,
C, Bolosiu, H, Melo-gomes, J, Tornero-molina, J, Wajdula, J, Pedersen, R,
Fatenejad, S, Tempo Study Invest
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 1063-1074
Year: 2006
Addresses:
· UNIV HOSP MAASTRICT, Dept Rheumatol, Maastricht, Netherlands
· KAROLINSKA INST, Stockholm, Sweden
· UNIV CANTABRIA, Hosp Marques Valdecilla, Santander, Spain
· Cent Methodol Reumatol, Bucharest, Romania
· Clin Reumatol, Cluj Napoca, Romania
· INST PORTUGUES REUMATOL, Lisbon, Portugal
· UNIV GUADALAJARA, Guadalajara, Spain
· WYETH AYERST RES, Collegeville, PA, USA
· Univ Hosp Maastrict, Dept Rheumatol, POB 5800, Maastricht,
Netherlands
***Article 16
Total Cites: 46
Article Title: Predictors of joint damage in patients with early rheumatoid
arthritis treated with high-dose methotrexate with or without concomitant
infliximab - Results from the ASPIRE trial
Authors: Smolen, JS, van der Heijde, DMFM, St Clair, EW, Emery, P, Bathon,
JM, Keystone, E, Maini, RN, Kalden, JR, Schiff, M, Baker, D, Han, CL, Han,
J, Bala, M, Aspire Study Grp
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 702-710
Year: 2006
Addresses:
· DUKE UNIV, Med Ctr, Durham, NC, USA
· MED UNIV VIENNA, Vienna, Austria
· LAINZ HOSP, Vienna, Austria
· UNIV MAASTRICHT, Maastricht, Netherlands
· UNIV LEEDS, Leeds, England
· JOHNS HOPKINS UNIV, Baltimore, MD, USA
· UNIV TORONTO, Toronto, Canada
· KENNEDY INST, London, England
· UNIV ERLANGEN NURNBERG, Erlangen, Germany
· DENVER ARTHRIT CLIN, Denver, CO, USA
· CENTOCOR INC, Malvern, PA, USA
· Duke Univ, Med Ctr, Box 3874, Durham, NC, USA
***Article 17
Total Cites: 43
Article Title: Circulating levels of B lymphocyte stimulator in patients
with rheumatoid arthritis following rituximab treatment - Relationships
with B cell depletion, circulating antibodies, and clinical relapse
Authors: Cambridge, G, Stohl, W, Leandro, MJ, Migone, TS, Hilbert, DM,
Edwards, JCW
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 723-732
Year: 2006
Addresses:
· UCL, London, England
· UNIV SO CALIF, Keck Sch Med, Los Angeles, CA, USA
· HUMAN GENOME SCI INC, Rockville, MD, USA
· UCL, Arthur Stanley House,Tottenham St, London, England
***Article 18
Total Cites: 40
Article Title: Safety of the selective costimulation modulator abatacept in
rheumatoid arthritis patients receiving background biologic and nonbiologic
disease-modifying antirheumatic drugs - A one-year randomized,
placebo-controlled study
Authors: Weinblatt, M, Combe, B, Covucci, A, Aranda, R, Becker, JC,
Keystone, E
Journal: ARTHRITIS AND RHEUMATISM
Volume: 54
Page: 2807-2816
Year: 2006
Addresses:
· BRIGHAM & WOMENS HOSP, Boston, MA, USA
· BRISTOL MYERS SQUIBB CO, Princeton, NJ, USA
· HOP LAPEYRONIE, Montpellier, France
· MT SINAI HOSP, Toronto, Canada
· Brigham & Womens Hosp, 75 Francis St, Boston, MA, USA
***Article 19
Total Cites: 36
Article Title: Safety of low dose glucocorticoid treatment in rheumatoid
arthritis: published evidence and prospective trial data
Authors: Da Silva, JAP, Jacobs, JWG, Kirwan, JR, Boers, M, Saag, KG, Ines,
LBS, de Koning, EJP, Buttgereit, F, Cutolo, M, Capell, H, Rau, R, Bijlsma,
JWJ
Journal: ANNALS OF THE RHEUMATIC DISEASES
Volume: 65
Page: 285-293
Year: 2006
Addresses:
· UNIV HOSP, Coimbra, Portugal
· UNIV UTRECHT, Med Ctr, Dept Rheumatol & Clin Immunol, Utrecht,
Netherlands
· UNIV BRISTOL, Bristol Royal Infirm, Acad Rheumatol Unit, Bristol,
England
· FREE UNIV AMSTERDAM, Med Ctr, Dept Clin Epidemiol & Biostat,
Amsterdam, Netherlands
· UNIV ALABAMA, Dept Clin Immunol & Rheumatol, Birmingham, AL,
USA
· LEIDEN UNIV, Med Ctr, Dept Nephrol, Leiden, Netherlands
· LEIDEN UNIV, Med Ctr, Dept Endocrinol, Leiden, Netherlands
· Charite Univ Med Berlin, Berlin, Germany
· UNIV GENOA, Res Lab, Genoa, Italy
· UNIV GENOA, Dept Internal Med, Div Rheumatol, Genoa, Italy
· GLASGOW ROYAL INFIRM, Ctr Rheumat Dis, Glasgow, Scotland
· EVANGEL FACHKRANKENHAUS, Dept Rheumatol, Ratingen, Germany
· Univ Hosp, Coimbra, Portugal
***Article 20
Total Cites: 35
Article Title: Anti-tumor necrosis factor-alpha blockade improves insulin
resistance in patients with rheumatoid arthritis
Authors: Gonzalez-gay, MA, De Matias, JM, Gonzalez-juanatey, C,
Garcia-porrua, C, Sanchez-andrade, A, Martin, J, Llorca, J
Journal: CLINICAL AND EXPERIMENTAL RHEUMATOLOGY
Volume: 24
Page: 83-86
Year: 2006
Addresses:
· HOSP XERAL CALDE, Div Rheumatol, Lugo, Spain
· HOSP XERAL CALDE, Div Endocrinol, Lugo, Spain
· HOSP XERAL CALDE, Div Cardiol, Lugo, Spain
· CSIC, Inst Parasitol & Biomed Lopez Neyra, Granada,
Spain
· UNIV CANTABRIA, Sch Med, Div Prevent Med & Publ Hlth,
Santander, Spain
· Hosp Xeral Calde, Div Rheumatol, C Dr Ochoa S-N, Lugo, Spain