As part of this bimonthly processing,
ScienceWatch.com selects the Research Fronts with the largest absolute
increase in size in each of the 22 major
fields covered by
Essential Science IndicatorsSM
from Thomson
Reuters. The size of a research front is determined by the number of
core papers it contains. This Research Front on IMAGING INTRACELLULAR
FLUORESCENT PROTEINS from the field of
Multidisciplinary was
selected for mapping from the list of Top Topics for
October 2009 (data
from the third bimonthly period of
2009). The map is a diagrammatic
representation of the 37 core papers comprising the front
in
Multidisciplinary.
Each circle
represents a highly cited paper whose bibliographic information is displayed
when the user clicks on the circle. The lines between circles represent the
strongest co-citation links for each paper (that is, indicating that the papers
are frequently cited together). Papers close to each other on the map are
generally more highly co-cited. The most recent paper(s) are indicated in pink.
Annotations may have been added to this map which represent the main research
themes. These appear as labels attached to specific regions on the maps.
Core Papers
Label: Shaner-2004 Title: Improved monomeric red, orange and yellow fluorescent proteins derived from Discosoma sp red fluorescent protein Journal: NAT BIOTECHNOL, 22 (12): 1567-1572 DEC 2004 Citations: 671 Authors: Shaner, NC;Campbell, RE;Steinbach, PA;Giepmans, BNG;Palmer, AE;Tsien, RY Addresses:
Univ Calif San Diego, Dept Pharmacol, 9500 Gilman Dr, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Neurosci, La Jolla, CA 92093 USA
Univ Calif San Diego, Natl Ctr Microscopy & Imaging Res, La Jolla, CA 92093 USA
Univ Calif San Diego, Howard Hughes Med Inst, La Jolla, CA 92093 USA
Label: Betzig-2006 Title: Imaging intracellular fluorescent proteins at nanometer resolution Journal: SCIENCE, 313 (5793): 1642-1645 SEP 15 2006 Citations: 181 Authors: Betzig, E;Patterson, GH;Sougrat, R;Lindwasser, OW;Olenych, S;Bonifacino, JS;Davidson, MW;Lippincott-Schwartz, J;Hess, HF Addresses:
Howard Hughes Med Inst, Janelia Farm Res Campus, Ashburn, VA USA
Howard Hughes Med Inst, Ashburn, VA USA
New Millennium Res LLC, Okemos, MI 48864 USA
NICHHD, Cell Biol & Metab Branch, Bethesda, MD 20892 USA
Florida State Univ, Natl High Magnet Field Lab, Tallahassee, FL 32310 USA
NuQuest Res LLC, La Jolla, CA 92037 USA
Label: Gustafsson-2005 Title: Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution Journal: PROC NAT ACAD SCI USA, 102 (37): 13081-13086 SEP 13 2005 Citations: 159 Authors: Gustafsson, MGL Addresses:
Univ Calif San Francisco, Dept Physiol, Box 0444, San Francisco, CA 94143 USA
Univ Calif San Francisco, Dept Physiol, San Francisco, CA 94143 USA
Univ Calif San Francisco, Bioengn Program, San Francisco, CA 94143 USA
Label: Hoffman-2005 Title: The multiple uses of fluorescent proteins to visualize cancer in vivo Journal: NAT REV CANCER, 5 (10): 796-806 OCT 2005 Citations: 107 Authors: Hoffman, RM Addresses:
AntiCanc Inc, 7917 Ostrow St, San Diego, CA 92111 USA
AntiCanc Inc, San Diego, CA 92111 USA
Univ Calif San Diego, Dept Surg, San Diego, CA 92111 USA
Label: Wang-2004 Title: Evolution of new nonantibody proteins via iterative somatic hypermutation Journal: PROC NAT ACAD SCI USA, 101 (48): 16745-16749 NOV 30 2004 Citations: 97 Authors: Wang, L;Jackson, WC;Steinbach, PA;Tsien, RY Addresses:
Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
Univ Calif San Diego, Howard Hughes Med Inst, La Jolla, CA 92093 USA
Label: Huang-2008 Title: Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy Journal: SCIENCE, 319 (5864): 810-813 FEB 8 2008 Citations: 74 Authors: Huang, B;Wang, WQ;Bates, M;Zhuang, XW Addresses:
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Dept Chem & Chem Biol, Cambridge, MA 02138 USA
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA
Label: Shu-2006 Title: Novel chromophores and buried charges control color in mFruits Journal: BIOCHEMISTRY-USA, 45 (32): 9639-9647 AUG 15 2006 Citations: 73 Authors: Shu, XK;Shaner, NC;Yarbrough, CA;Tsien, RY;Remington, SJ Addresses:
Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA
Univ Oregon, Inst Mol Biol, Eugene, OR 97403 USA
Univ Oregon, Dept Phys, Eugene, OR 97403 USA
Univ Calif San Diego, Howard Hughes Med Inst, Dept Pharmacol, La Jolla, CA 92093 USA
Univ Calif San Diego, Howard Hughes Med Inst, Dept Chem, La Jolla, CA 92093 USA
Label: Bates-2007 Title: Multicolor super-resolution imaging with photo-switchable fluorescent probes Journal: SCIENCE, 317 (5845): 1749-1753 SEP 21 2007 Citations: 67 Authors: Bates, M;Huang, B;Dempsey, GT;Zhuang, XW Addresses:
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Howard Hughes Med Inst, Cambridge, MA 02138 USA
Harvard Univ, Sch Engn & Appl Sci, Cambridge, MA 02138 USA
Harvard Univ, Dept Chem & Biol Chem, Cambridge, MA 02138 USA
Harvard Univ, Grad Program Biophys, Cambridge, MA 02138 USA
Harvard Univ, Dept Phys, Cambridge, MA 02138 USA
Label: Shaner-2007 Title: Advances in fluorescent protein technology Journal: J CELL SCI, 120 (24): 4247-4260 DEC 15 2007 Citations: 44 Authors: Shaner, NC;Patterson, GH;Davidson, MW Addresses:
Salk Inst Biol Studies, 10010 N Torrey Pines Rd, La Jolla, CA 92037 USA
Salk Inst Biol Studies, La Jolla, CA 92037 USA
NICHHD, Cell Biol & Metab Branch, Bethesda, MD 20892 USA
Florida State Univ, Natl High Magnet Field Lab, Tallahassee, FL 32310 USA
Florida State Univ, Dept Biol Sci, Tallahassee, FL 32310 USA
Label: Shroff-2007 Title: Dual-color superresolution imaging of genetically expressed probes within individual adhesion complexes Journal: PROC NAT ACAD SCI USA, 104 (51): 20308-20313 DEC 18 2007 Citations: 30 Authors: Shroff, H;Galbraith, CG;Galbraith, JA;White, H;Gillette, J;Olenych, S;Davidson, MW;Betzig, E Addresses:
Howard Hughes Med Inst, Ashburn, VA 20147 USA
Howard Hughes Med Inst, Ashburn, VA 20147 USA
Natl Inst Dent & Craniofacial Res, Bethesda, MD 20892 USA
NINDS, Bethesda, MD 20892 USA
NIH, NICHHD, Bethesda, MD 20892 USA
Florida State Univ, Dept Biol Sci, Natl High Magnet Field Lab, Tallahassee, FL 32310 USA
Label: Juette-2008 Title: Three-dimensional sub-100 nm resolution fluorescence microscopy of thick samples Journal: NAT METHODS, 5 (6): 527-529 JUN 2008 Citations: 29 Authors: Juette, MF;Gould, TJ;Lessard, MD;Mlodzianoski, MJ;Nagpure, BS;Bennett, BT;Hess, ST;Bewersdorf, J Addresses:
Jackson Lab, Inst Mol Biophys, 600 Main St, Bar Harbor, ME 04609 USA
Jackson Lab, Inst Mol Biophys, Bar Harbor, ME 04609 USA
Univ Maine, Inst Mol Biophys, Orono, ME 04469 USA
Univ Maine, Dept Phys & Astron, Orono, ME 04469 USA
Active Motif Inc, Carlsbad, CA 92008 USA
Max Planck Inst Met Res, Dept New Mat & Biosyst, D-70569 Stuttgart, Germany
Univ Heidelberg, Dept Biophys Chem, D-70569 Stuttgart, Germany
Label: Shaner-2008 Title: Improving the photostability of bright monomeric orange and red fluorescent proteins Journal: NAT METHODS, 5 (6): 545-551 JUN 2008 Citations: 24 Authors: Shaner, NC;Lin, MZ;McKeown, MR;Steinbach, PA;Hazelwood, KL;Davidson, MW;Tsien, RY Addresses:
Univ Calif San Diego, Dept Pharmacol, 9500 Gilman Dr, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Pharmacol, La Jolla, CA 92093 USA
Univ Calif San Diego, Howard Hughes Med Inst, La Jolla, CA 92093 USA
Univ Calif San Diego, Dept Chem & Biochem, La Jolla, CA 92093 USA
Florida State Univ, Dept Biol Sci, Tallahassee, FL 32310 USA
Florida State Univ, Natl High Magnet Field Lab, Tallahassee, FL 32310 USA