The
Best of Biology in the 1990's
The legacies of two famed industrialists—Howard Hughes
and Sir Henry Wellcome—stand out strongly in a new Science Watch survey of
high-impact biomedical research in the 1990s. Scientists employed by the Howard Hughes
Medical Institute (HHMI) have produced the ...
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 TIGR's
J. Craig Venter on Sequences, Consequences
The story of how J. Craig Venter brought about a
paradigm shift in genomic sequencing has now entered the mythology of science. In 1987,
Venter, a former surf-bum and Vietnam medic, was researching adrenaline receptors at the
National Institute of Neurological Disorders and Strokes (NINDS) when he read a paper by
Caltech's Leroy Hood in Nature about an automatic gene sequencer. Venter's lab had
just spent a year sequencing its first gene, so he got his hands on the first commercial
automatic sequencer, and his lab may have been the first to make it work. He then pushed
the idea of using cDNA libraries and Expressed Sequence Tags (EST) for sequencing, and
when the National Institutes of Health (NIH) ... |
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