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FAST MOVING FRONTS

Research Front Map - July 2008

This Research Front on THERAPEUTIC EFFECTS OF CURCUMIN from the field of Pharmacology & Toxicology was selected for mapping from the list of Fast Moving Fronts for July 2008 (data from the first bimonthly period of 2008). The map is a diagrammatic representation of the 19 core papers comprising the front. Each circle represents a highly cited paper whose bibliographic information is displayed when the user clicks on the circle. The lines between circles represent the strongest co-citation links for each paper (that is, indicating that the papers are frequently cited together). Papers close to each other on the map are generally more highly co-cited. The most recent paper(s) are indicated in pink.

Garg-2002 Bharti-2003 Aggarwal-2003 Joe-2004 Egan-2004 Shishodia-2004 Aggarwal-2004 Dorai-2004 Nakanishi-2005 Duvoix-2005 Shishodia-2005 Sharma-2005 Luo-2005 Aggarwal-2006 Hoehle-2006 Shishodia-2005 Jiang-2006 Maheshwari-2006 Aggarwal-2006
THERAPEUTIC EFFECTS OF CURCUMIN

Core Papers

Label: Aggarwal-2003
Title: Anticancer potential of curcumin: Preclinical and clinical studies
Journal: ANTICANCER RES, 23 (1A): 363-398 JAN-FEB 2003
Citations: 250
Authors: Aggarwal, BB;Kumar, A;Bharti, AC
Addresses:
Univ Texas, MD Anderson Canc Ctr, Cytokine Res Sect, Dept Bioimmunotherapy, 1515 Holcombe Blvd,Box 143, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Cytokine Res Sect, Dept Bioimmunotherapy, Houston, TX 77030 USA


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Label: Aggarwal-2004
Title: Nuclear factor-kappa-B: The enemy within
Journal: CANCER CELL, 6 (3): 203-208 SEP 2004
Citations: 233
Authors: Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Lab, 1515 Holcombe Blvd,Unit 143, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Lab, Houston, TX 77030 USA


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Label: Bharti-2003
Title: Curcumin (diferuloylmethane) down-regulates the constitutive activation of nuclear factor-kappa B and I kappa B alpha kinase in human multiple myeloma cells, leading to suppression of proliferation and induction of apoptosis
Journal: BLOOD, 101 (3): 1053-1062 FEB 1 2003
Citations: 166
Authors: Bharti, AC;Donato, N;Singh, S;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Bioimmunotherapy, Cytokine Res Stn, Box 143,1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Bioimmunotherapy, Cytokine Res Stn, Houston, TX 77030 USA
Imgenex, San Diego, CA USA


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Label: Garg-2002
Title: Nuclear transcription factor-kappa B as a target for cancer drug development
Journal: LEUKEMIA, 16 (6): 1053-1068 JUN 2002
Citations: 143
Authors: Garg, A;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Bioimmunotherapy, Cytokine Res Lab, Box 143,1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Bioimmunotherapy, Cytokine Res Lab, Houston, TX 77030 USA


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Label: Nakanishi-2005
Title: Nuclear factor-kappa B inhibitors as sensitizers to anticancer drugs
Journal: NAT REV CANCER, 5 (4): 297-309 APR 2005
Citations: 122
Authors: Nakanishi, C;Toi, M
Addresses:
Komagome Hosp, Tokyo Metropolitan Canc & Infect Dis Ctr, Bunkyo Ku, 3-18-22 Honkomagome, Tokyo 1138677, Japan
Komagome Hosp, Tokyo Metropolitan Canc & Infect Dis Ctr, Bunkyo Ku, Tokyo 1138677, Japan


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Label: Egan-2004
Title: Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects
Journal: SCIENCE, 304 (5670): 600-602 APR 23 2004
Citations: 121
Authors: Egan, ME;Pearson, M;Weiner, SA;Rajendran, V;Rubin, D;Glockner-Pagel, J;Canny, S;Du, K;Lukacs, GL;Caplan, MJ
Addresses:
Yale Univ, Sch Med, Dept Cellular & Mol Physiol, 333 Cedar St,POB 208026, New Haven, CT 06520 USA
Yale Univ, Sch Med, Dept Cellular & Mol Physiol, New Haven, CT 06520 USA
Yale Univ, Sch Med, Dept Pediat, New Haven, CT 06520 USA
Univ Toronto, Hosp Sick Children, Res Inst, Dept Lab Med & Pathol,Program Cell & Lung Biol, Toronto, ON M5G 1X8, Canada


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Label: Luo-2005
Title: IKK/NF-kappa B signaling: balancing life and death - a new approach to cancer therapy
Journal: J CLIN INVEST, 115 (10): 2625-2632 OCT 2005
Citations: 114
Authors: Luo, JL;Kamata, H;Karin, M
Addresses:
Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, Dept Pharmacol & Canc Ctr, 9500 Gilman Dr, La Jolla, CA 92093 USA
Univ Calif San Diego, Sch Med, Lab Gene Regulat & Signal Transduct, Dept Pharmacol & Canc Ctr, La Jolla, CA 92093 USA


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Label: Aggarwal-2006
Title: Molecular targets of dietary agents for prevention and therapy of cancer
Journal: BIOCHEM PHARMACOL, 71 (10): 1397-1421 MAY 14 2006
Citations: 86
Authors: Aggarwal, BB;Shishodia, S
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Lab, Box 143,1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Lab, Houston, TX 77030 USA
Texas So Univ, Dept Biol, Houston, TX 77004 USA


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Label: Sharma-2005
Title: Curcumin: The story so far
Journal: EUR J CANCER, 41 (13): 1955-1968 SEP 2005
Citations: 84
Authors: Sharma, RA;Gescher, AJ;Steward, WP
Addresses:
Royal Marsden Hosp, Dept Radiotherapy, NHS Trust, Downs Rd, Sutton SM2 5PT, Surrey, England
Univ Leicester, Leicester Royal Infirm, Canc Biomarkers & Prevent Grp, Dept Canc Studies & Mol Med, Leicester LE2 7LX, Leics, England


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Label: Dorai-2004
Title: Role of chemopreventive agents in cancer therapy
Journal: CANCER LETT, 215 (2): 129-140 NOV 25 2004
Citations: 83
Authors: Dorai, T;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Sect, 1515 Holcombe Blvd,Box 143, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Sect, Houston, TX 77030 USA
New York Med Coll, Our Lady Mercy Med Ctr, Ctr Comprehens Canc, Bronx, NY 10466 USA


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Label: Shishodia-2004
Title: Nuclear factor-KB: a friend or a foe in cancer?
Journal: BIOCHEM PHARMACOL, 68 (6): 1071-1080 SEP 15 2004
Citations: 81
Authors: Shishodia, S;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Cytokine Res Sect, Dept Bioimmunotherapy,Unit 143, 1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Cytokine Res Sect, Dept Bioimmunotherapy,Unit 143, Houston, TX 77030 USA


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Label: Joe-2004
Title: Biological properties of curcumin-cellular and molecular mechanisms of action
Journal: CRIT REV FOOD SCI NUTR, 44 (2): 97-111 2004
Citations: 68
Authors: Joe, B;Vijaykumar, M;Lokesh, BR
Addresses:
Med Coll Ohio, Dept Physiol & Mol Med, 319 Block Hlth Sci Bldg,3035 Arlington Ave, Toledo, OH 43614 USA
Med Coll Ohio, Dept Physiol & Mol Med, Toledo, OH 43614 USA
Johns Hopkins Med Inst, Dept Pathol, Immunol Lab, Baltimore, MD 21287 USA
Cent Food Technol Res Inst, Dept Lipid Sci & Tradit Foods, Mysore 570013, Karnataka, India


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Label: Duvoix-2005
Title: Chemopreventive and therapeutic effects of curcumin
Journal: CANCER LETT, 223 (2): 181-190 JUN 8 2005
Citations: 67
Authors: Duvoix, A;Blasius, R;Delhalle, S;Schnekenburger, M;Morceau, F;Henry, E;Dicato, M;Diederich, M
Addresses:
Hop Kirchberg, Lab Biol Mol & Cellulaire Canc, 9 Rue Edward Steichen, L-2540 Luxembourg, Luxembourg
Hop Kirchberg, Lab Biol Mol & Cellulaire Canc, L-2540 Luxembourg, Luxembourg


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Label: Shishodia-2005
Title: Curcumin (diferuloylmethane) inhibits constitutive NF-kappa B activation, induces G1/S arrest, suppresses proliferation, and induces apoptosis in mantle cell lymphoma
Journal: BIOCHEM PHARMACOL, 70 (5): 700-713 SEP 1 2005
Citations: 49
Authors: Shishodia, S;Amin, HM;Lai, R;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Sect, 1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Sect, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Hematopathol, Houston, TX 77030 USA


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Label: Shishodia-2005
Title: Curcumin: Getting back to the roots
Journal: ANN N Y ACAD SCI, 1056: 206-217 2005
Citations: 45
Authors: Shishodia, S;Sethi, G;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Box 143 1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Houston, TX 77030 USA


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Label: Maheshwari-2006
Title: Multiple biological activities of curcumin: A short review
Journal: LIFE SCI, 78 (18): 2081-2087 MAR 27 2006
Citations: 42
Authors: Maheshwari, RK;Singh, AK;Gaddipati, J;Srimal, RC
Addresses:
Uniformed Serv Univ Life Sci, Ctr Combat Casualty & Life Sustainment Res, Dept Pathol, 4301 Jones Bridge Rd, Bethesda, MD 20814 USA
Uniformed Serv Univ Life Sci, Ctr Combat Casualty & Life Sustainment Res, Dept Pathol, Bethesda, MD 20814 USA
Ind Toxicol Res Ctr, Lucknow, Uttar Pradesh, India


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Label: Aggarwal-2006
Title: Curcumin (diferuloylmethane) down-regulates expression of cell proliferation and antiapoptotic and metastatic gene products through suppression of I kappa B alpha kinase and Akt activation
Journal: MOL PHARMACOL, 69 (1): 195-206 JAN 2006
Citations: 41
Authors: Aggarwal, S;Ichikawa, H;Takada, Y;Sandur, SK;Shishodia, S;Aggarwal, BB
Addresses:
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Lab, Box 143,1515 Holcombe Blvd, Houston, TX 77030 USA
Univ Texas, MD Anderson Canc Ctr, Dept Expt Therapeut, Cytokine Res Lab, Houston, TX 77030 USA


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Label: Hoehle-2006
Title: Metabolism of curcuminoids in tissue slices and subcellular fractions from rat liver
Journal: J AGR FOOD CHEM, 54 (3): 756-764 FEB 8 2006
Citations: 11
Authors: Hoehle, SI;Pfeiffer, E;Solyom, AM;Metzler, M
Addresses:
Univ Karlsruhe, Sect Food Chem & Toxicol, Inst Appl Biosci, POB 6980, D-76128 Karlsruhe, Germany
Univ Karlsruhe, Sect Food Chem & Toxicol, Inst Appl Biosci, D-76128 Karlsruhe, Germany
Univ Arizona, Coll Pharm, Tucson, AZ 85721 USA


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Label: Jiang-2006
Title: Analysis of curcuminoids by positive and negative electrospray ionization and tandem mass spectrometry
Journal: RAPID COMMUN MASS SPECTROM, 20 (6): 1001-1012 2006
Citations: 9
Authors: Jiang, HL;Somogyi, A;Jacobsen, NE;Timmermann, BN;Gang, DR
Addresses:
Univ Arizona, Dept Plant Sci, Tucson, AZ 85721 USA
Univ Arizona, Dept Plant Sci, Tucson, AZ 85721 USA
Univ Arizona, Bio5 Inst, Tucson, AZ 85721 USA
Univ Arizona, Arizona Ctr Phytomed Res, Tucson, AZ 85721 USA
Univ Arizona, Dept Pharmaceut Sci, Tucson, AZ 85721 USA
Univ Arizona, Dept Chem, Tucson, AZ 85721 USA
Univ Arizona, Dept Pharmacol & Toxicol, Tucson, AZ 85721 USA


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Keywords: CURCUMIN (DIFERULOYLMETHANE) INHIBITS CONSTITUTIVE NF-KAPPA B ACTIVATION; I KAPPA B ALPHA KINASE; NUCLEAR FACTOR-KAPPA B INHIBITORS; NUCLEAR TRANSCRIPTION FACTOR-KAPPA B; CURCUMIN (DIFERULOYLMETHANE) DOWN-REGULATES EXPRESSION.



Fast Moving Fronts : Maps : THERAPEUTIC EFFECTS OF CURCUMIN - Research Front Map